Transcription factor | IRF3 (GeneCards) | ||||||||
Model | IRF3_HUMAN.H11DI.0.B | ||||||||
Model type | Dinucleotide PWM | ||||||||
LOGO | |||||||||
LOGO (reverse complement) | |||||||||
Data source | ChIP-Seq | ||||||||
Model release | HOCOMOCOv11 | ||||||||
Model length | 23 | ||||||||
Quality | B | ||||||||
Motif rank | 0 | ||||||||
Consensus | nvdRRMdRGAAAvnGAAAvndvv | ||||||||
Best auROC (human) | 0.797 | ||||||||
Best auROC (mouse) | 0.962 | ||||||||
Peak sets in benchmark (human) | 6 | ||||||||
Peak sets in benchmark (mouse) | 21 | ||||||||
Aligned words | 510 | ||||||||
TF family | Interferon-regulatory factors {3.5.3} | ||||||||
TF subfamily | IRF-3 {3.5.3.0.3} | ||||||||
HGNC | HGNC:6118 | ||||||||
EntrezGene | GeneID:3661 (SSTAR profile) | ||||||||
UniProt ID | IRF3_HUMAN | ||||||||
UniProt AC | Q14653 (TFClass) | ||||||||
Comment | |||||||||
Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
Standard thresholds |
| ||||||||
GTEx tissue expression atlas | IRF3 expression | ||||||||
ReMap ChIP-seq dataset list | IRF3 datasets | ||||||||
Motifs in JASPAR |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 43.0 | 31.0 | 46.0 | 7.0 | 35.0 | 14.0 | 5.0 | 14.0 | 30.0 | 16.0 | 44.0 | 7.0 | 14.0 | 17.0 | 22.0 | 8.0 |
02 | 47.0 | 7.0 | 51.0 | 17.0 | 56.0 | 1.0 | 14.0 | 7.0 | 47.0 | 5.0 | 54.0 | 11.0 | 16.0 | 1.0 | 11.0 | 8.0 |
03 | 88.0 | 2.0 | 74.0 | 2.0 | 7.0 | 2.0 | 1.0 | 4.0 | 92.0 | 2.0 | 33.0 | 3.0 | 12.0 | 2.0 | 25.0 | 4.0 |
04 | 139.0 | 2.0 | 50.0 | 8.0 | 4.0 | 1.0 | 0.0 | 3.0 | 98.0 | 6.0 | 20.0 | 9.0 | 4.0 | 1.0 | 7.0 | 1.0 |
05 | 205.0 | 16.0 | 11.0 | 13.0 | 6.0 | 1.0 | 0.0 | 3.0 | 61.0 | 6.0 | 7.0 | 3.0 | 7.0 | 4.0 | 5.0 | 5.0 |
06 | 146.0 | 33.0 | 59.0 | 41.0 | 13.0 | 3.0 | 1.0 | 10.0 | 12.0 | 3.0 | 6.0 | 2.0 | 3.0 | 1.0 | 11.0 | 9.0 |
07 | 29.0 | 7.0 | 121.0 | 17.0 | 10.0 | 14.0 | 7.0 | 9.0 | 18.0 | 4.0 | 47.0 | 8.0 | 11.0 | 5.0 | 42.0 | 4.0 |
08 | 14.0 | 0.0 | 54.0 | 0.0 | 18.0 | 0.0 | 12.0 | 0.0 | 18.0 | 1.0 | 198.0 | 0.0 | 1.0 | 0.0 | 37.0 | 0.0 |
09 | 44.0 | 0.0 | 7.0 | 0.0 | 1.0 | 0.0 | 0.0 | 0.0 | 267.0 | 3.0 | 31.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
10 | 294.0 | 0.0 | 17.0 | 1.0 | 3.0 | 0.0 | 0.0 | 0.0 | 36.0 | 1.0 | 0.0 | 1.0 | 0.0 | 0.0 | 0.0 | 0.0 |
11 | 320.0 | 2.0 | 6.0 | 5.0 | 1.0 | 0.0 | 0.0 | 0.0 | 16.0 | 1.0 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 0.0 |
12 | 38.0 | 177.0 | 104.0 | 20.0 | 0.0 | 3.0 | 0.0 | 0.0 | 0.0 | 1.0 | 4.0 | 1.0 | 0.0 | 5.0 | 0.0 | 0.0 |
13 | 13.0 | 2.0 | 13.0 | 10.0 | 64.0 | 45.0 | 15.0 | 62.0 | 18.0 | 11.0 | 47.0 | 32.0 | 4.0 | 4.0 | 8.0 | 5.0 |
14 | 16.0 | 3.0 | 78.0 | 2.0 | 27.0 | 1.0 | 32.0 | 2.0 | 5.0 | 2.0 | 74.0 | 2.0 | 10.0 | 1.0 | 97.0 | 1.0 |
15 | 49.0 | 1.0 | 6.0 | 2.0 | 3.0 | 2.0 | 0.0 | 2.0 | 230.0 | 10.0 | 33.0 | 8.0 | 4.0 | 1.0 | 1.0 | 1.0 |
16 | 265.0 | 10.0 | 6.0 | 5.0 | 12.0 | 1.0 | 0.0 | 1.0 | 35.0 | 3.0 | 2.0 | 0.0 | 6.0 | 0.0 | 6.0 | 1.0 |
17 | 276.0 | 8.0 | 18.0 | 16.0 | 8.0 | 0.0 | 0.0 | 6.0 | 9.0 | 3.0 | 0.0 | 2.0 | 2.0 | 1.0 | 1.0 | 3.0 |
18 | 40.0 | 134.0 | 105.0 | 16.0 | 4.0 | 2.0 | 1.0 | 5.0 | 2.0 | 6.0 | 5.0 | 6.0 | 3.0 | 7.0 | 14.0 | 3.0 |
19 | 15.0 | 9.0 | 8.0 | 17.0 | 53.0 | 42.0 | 2.0 | 52.0 | 32.0 | 22.0 | 36.0 | 35.0 | 7.0 | 4.0 | 8.0 | 11.0 |
20 | 34.0 | 10.0 | 52.0 | 11.0 | 36.0 | 15.0 | 12.0 | 14.0 | 12.0 | 2.0 | 38.0 | 2.0 | 21.0 | 18.0 | 56.0 | 20.0 |
21 | 53.0 | 8.0 | 33.0 | 9.0 | 25.0 | 10.0 | 3.0 | 7.0 | 90.0 | 21.0 | 37.0 | 10.0 | 12.0 | 7.0 | 19.0 | 9.0 |
22 | 93.0 | 14.0 | 56.0 | 17.0 | 15.0 | 11.0 | 5.0 | 15.0 | 33.0 | 20.0 | 28.0 | 11.0 | 5.0 | 11.0 | 12.0 | 7.0 |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 0.659 | 0.335 | 0.726 | -1.113 | 0.455 | -0.445 | -1.43 | -0.445 | 0.303 | -0.315 | 0.682 | -1.113 | -0.445 | -0.256 | -0.003 | -0.986 |
02 | 0.748 | -1.113 | 0.829 | -0.256 | 0.922 | -2.798 | -0.445 | -1.113 | 0.748 | -1.43 | 0.885 | -0.68 | -0.315 | -2.798 | -0.68 | -0.986 |
03 | 1.371 | -2.249 | 1.199 | -2.249 | -1.113 | -2.249 | -2.798 | -1.636 | 1.415 | -2.249 | 0.397 | -1.896 | -0.595 | -2.249 | 0.123 | -1.636 |
04 | 1.827 | -2.249 | 0.809 | -0.986 | -1.636 | -2.798 | -4.114 | -1.896 | 1.478 | -1.259 | -0.096 | -0.873 | -1.636 | -2.798 | -1.113 | -2.798 |
05 | 2.214 | -0.315 | -0.68 | -0.518 | -1.259 | -2.798 | -4.114 | -1.896 | 1.007 | -1.259 | -1.113 | -1.896 | -1.113 | -1.636 | -1.43 | -1.43 |
06 | 1.876 | 0.397 | 0.973 | 0.612 | -0.518 | -1.896 | -2.798 | -0.772 | -0.595 | -1.896 | -1.259 | -2.249 | -1.896 | -2.798 | -0.68 | -0.873 |
07 | 0.269 | -1.113 | 1.688 | -0.256 | -0.772 | -0.445 | -1.113 | -0.873 | -0.2 | -1.636 | 0.748 | -0.986 | -0.68 | -1.43 | 0.636 | -1.636 |
08 | -0.445 | -4.114 | 0.885 | -4.114 | -0.2 | -4.114 | -0.595 | -4.114 | -0.2 | -2.798 | 2.18 | -4.114 | -2.798 | -4.114 | 0.51 | -4.114 |
09 | 0.682 | -4.114 | -1.113 | -4.114 | -2.798 | -4.114 | -4.114 | -4.114 | 2.478 | -1.896 | 0.335 | -4.114 | -4.114 | -4.114 | -4.114 | -4.114 |
10 | 2.574 | -4.114 | -0.256 | -2.798 | -1.896 | -4.114 | -4.114 | -4.114 | 0.483 | -2.798 | -4.114 | -2.798 | -4.114 | -4.114 | -4.114 | -4.114 |
11 | 2.659 | -2.249 | -1.259 | -1.43 | -2.798 | -4.114 | -4.114 | -4.114 | -0.315 | -2.798 | -4.114 | -4.114 | -2.249 | -4.114 | -4.114 | -4.114 |
12 | 0.537 | 2.068 | 1.538 | -0.096 | -4.114 | -1.896 | -4.114 | -4.114 | -4.114 | -2.798 | -1.636 | -2.798 | -4.114 | -1.43 | -4.114 | -4.114 |
13 | -0.518 | -2.249 | -0.518 | -0.772 | 1.054 | 0.704 | -0.378 | 1.023 | -0.2 | -0.68 | 0.748 | 0.367 | -1.636 | -1.636 | -0.986 | -1.43 |
14 | -0.315 | -1.896 | 1.251 | -2.249 | 0.199 | -2.798 | 0.367 | -2.249 | -1.43 | -2.249 | 1.199 | -2.249 | -0.772 | -2.798 | 1.468 | -2.798 |
15 | 0.789 | -2.798 | -1.259 | -2.249 | -1.896 | -2.249 | -4.114 | -2.249 | 2.329 | -0.772 | 0.397 | -0.986 | -1.636 | -2.798 | -2.798 | -2.798 |
16 | 2.471 | -0.772 | -1.259 | -1.43 | -0.595 | -2.798 | -4.114 | -2.798 | 0.455 | -1.896 | -2.249 | -4.114 | -1.259 | -4.114 | -1.259 | -2.798 |
17 | 2.511 | -0.986 | -0.2 | -0.315 | -0.986 | -4.114 | -4.114 | -1.259 | -0.873 | -1.896 | -4.114 | -2.249 | -2.249 | -2.798 | -2.798 | -1.896 |
18 | 0.588 | 1.79 | 1.547 | -0.315 | -1.636 | -2.249 | -2.798 | -1.43 | -2.249 | -1.259 | -1.43 | -1.259 | -1.896 | -1.113 | -0.445 | -1.896 |
19 | -0.378 | -0.873 | -0.986 | -0.256 | 0.867 | 0.636 | -2.249 | 0.848 | 0.367 | -0.003 | 0.483 | 0.455 | -1.113 | -1.636 | -0.986 | -0.68 |
20 | 0.427 | -0.772 | 0.848 | -0.68 | 0.483 | -0.378 | -0.595 | -0.445 | -0.595 | -2.249 | 0.537 | -2.249 | -0.049 | -0.2 | 0.922 | -0.096 |
21 | 0.867 | -0.986 | 0.397 | -0.873 | 0.123 | -0.772 | -1.896 | -1.113 | 1.394 | -0.049 | 0.51 | -0.772 | -0.595 | -1.113 | -0.147 | -0.873 |
22 | 1.426 | -0.445 | 0.922 | -0.256 | -0.378 | -0.68 | -1.43 | -0.378 | 0.397 | -0.096 | 0.235 | -0.68 | -1.43 | -0.68 | -0.595 | -1.113 |