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Model info
Transcription factorLEF1
(GeneCards)
ModelLEF1_HUMAN.H11DI.0.A
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length18
Quality
A
Motif rank
0
ConsensusnYYWTTSWdvTKYWdWbn
Best auROC (human)0.912
Best auROC (mouse)
Peak sets in benchmark (human)20
Peak sets in benchmark (mouse)
Aligned words496
TF familyTCF-7-related factors {4.1.3}
TF subfamilyLEF-1 (TCF-1alpha) [1] {4.1.3.0.4}
HGNCHGNC:6551
EntrezGeneGeneID:51176
(SSTAR profile)
UniProt IDLEF1_HUMAN
UniProt ACQ9UJU2
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 11.484110000000001
0.0005 13.24676
0.0001 16.87036
GTEx tissue expression atlas LEF1 expression
ReMap ChIP-seq dataset list LEF1 datasets
Motifs in JASPAR
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
012.033.019.014.08.080.011.047.00.069.022.021.05.0100.034.031.0
021.010.00.04.015.0167.05.095.03.063.011.09.09.080.04.020.0
038.01.00.019.063.015.01.0241.05.01.03.011.036.03.03.086.0
046.01.01.0104.02.00.00.018.00.00.00.07.05.09.06.0337.0
057.00.00.06.01.00.00.09.00.00.00.07.023.04.08.0431.0
063.011.017.00.01.01.01.01.03.01.02.02.024.0117.0296.016.0
0722.01.00.08.090.06.02.032.0191.09.05.0111.013.01.00.05.0
08156.017.049.094.06.02.00.09.02.01.02.02.024.030.033.069.0
09119.011.047.011.042.02.00.06.056.02.014.012.069.052.033.020.0
107.03.01.0275.02.010.00.055.02.04.04.084.01.00.01.047.0
110.01.04.07.01.01.07.08.02.00.01.03.01.029.0334.097.0
120.03.01.00.00.018.04.09.09.0196.044.097.08.077.013.017.0
138.02.02.05.0188.019.05.082.034.010.010.08.072.07.07.037.0
14154.034.077.037.017.06.04.011.09.04.06.05.067.016.026.023.0
15198.07.020.022.025.05.05.025.065.023.012.013.022.010.015.029.0
1641.032.054.0183.02.011.04.028.015.016.08.013.05.023.018.043.0
1716.019.014.014.025.015.09.033.018.021.024.021.044.041.091.091.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
01-2.5760.062-0.482-0.78-1.320.94-1.0140.412-4.3930.793-0.338-0.384-1.7621.1630.0910.0
02-3.119-1.106-4.393-1.968-0.7131.674-1.7621.112-2.2260.703-1.014-1.207-1.2070.94-1.968-0.431
03-1.32-3.119-4.393-0.4820.703-0.713-3.1192.04-1.762-3.119-2.226-1.0140.148-2.226-2.2261.012
04-1.592-3.119-3.1191.202-2.576-4.393-4.393-0.535-4.393-4.393-4.393-1.447-1.762-1.207-1.5922.375
05-1.447-4.393-4.393-1.592-3.119-4.393-4.393-1.207-4.393-4.393-4.393-1.447-0.294-1.968-1.322.621
06-2.226-1.014-0.591-4.393-3.119-3.119-3.119-3.119-2.226-3.119-2.576-2.576-0.2521.3192.245-0.65
07-0.338-3.119-4.393-1.321.058-1.592-2.5760.0311.808-1.207-1.7621.267-0.852-3.119-4.393-1.762
081.606-0.5910.4531.101-1.592-2.576-4.393-1.207-2.576-3.119-2.576-2.576-0.252-0.0320.0620.793
091.336-1.0140.412-1.0140.3-2.576-4.393-1.5920.586-2.576-0.78-0.930.7930.5120.062-0.431
10-1.447-2.226-3.1192.172-2.576-1.106-4.3930.568-2.576-1.968-1.9680.989-3.119-4.393-3.1190.412
11-4.393-3.119-1.968-1.447-3.119-3.119-1.447-1.32-2.576-4.393-3.119-2.226-3.119-0.0662.3661.132
12-4.393-2.226-3.119-4.393-4.393-0.535-1.968-1.207-1.2071.8340.3471.132-1.320.902-0.852-0.591
13-1.32-2.576-2.576-1.7621.792-0.482-1.7620.9650.091-1.106-1.106-1.320.836-1.447-1.4470.175
141.5930.0910.9020.175-0.591-1.592-1.968-1.014-1.207-1.968-1.592-1.7620.764-0.65-0.174-0.294
151.844-1.447-0.431-0.338-0.212-1.762-1.762-0.2120.734-0.294-0.93-0.852-0.338-1.106-0.713-0.066
160.2770.0310.551.765-2.576-1.014-1.968-0.1-0.713-0.65-1.32-0.852-1.762-0.294-0.5350.324
17-0.65-0.482-0.78-0.78-0.212-0.713-1.2070.062-0.535-0.384-0.252-0.3840.3470.2771.0691.069