Transcription factor | LEF1 (GeneCards) | ||||||||
Model | LEF1_HUMAN.H11DI.0.A | ||||||||
Model type | Dinucleotide PWM | ||||||||
LOGO | |||||||||
LOGO (reverse complement) | |||||||||
Data source | ChIP-Seq | ||||||||
Model release | HOCOMOCOv11 | ||||||||
Model length | 18 | ||||||||
Quality | A | ||||||||
Motif rank | 0 | ||||||||
Consensus | nYYWTTSWdvTKYWdWbn | ||||||||
Best auROC (human) | 0.912 | ||||||||
Best auROC (mouse) | |||||||||
Peak sets in benchmark (human) | 20 | ||||||||
Peak sets in benchmark (mouse) | |||||||||
Aligned words | 496 | ||||||||
TF family | TCF-7-related factors {4.1.3} | ||||||||
TF subfamily | LEF-1 (TCF-1alpha) [1] {4.1.3.0.4} | ||||||||
HGNC | HGNC:6551 | ||||||||
EntrezGene | GeneID:51176 (SSTAR profile) | ||||||||
UniProt ID | LEF1_HUMAN | ||||||||
UniProt AC | Q9UJU2 (TFClass) | ||||||||
Comment | |||||||||
Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
Standard thresholds |
| ||||||||
GTEx tissue expression atlas | LEF1 expression | ||||||||
ReMap ChIP-seq dataset list | LEF1 datasets | ||||||||
Motifs in JASPAR |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 2.0 | 33.0 | 19.0 | 14.0 | 8.0 | 80.0 | 11.0 | 47.0 | 0.0 | 69.0 | 22.0 | 21.0 | 5.0 | 100.0 | 34.0 | 31.0 |
02 | 1.0 | 10.0 | 0.0 | 4.0 | 15.0 | 167.0 | 5.0 | 95.0 | 3.0 | 63.0 | 11.0 | 9.0 | 9.0 | 80.0 | 4.0 | 20.0 |
03 | 8.0 | 1.0 | 0.0 | 19.0 | 63.0 | 15.0 | 1.0 | 241.0 | 5.0 | 1.0 | 3.0 | 11.0 | 36.0 | 3.0 | 3.0 | 86.0 |
04 | 6.0 | 1.0 | 1.0 | 104.0 | 2.0 | 0.0 | 0.0 | 18.0 | 0.0 | 0.0 | 0.0 | 7.0 | 5.0 | 9.0 | 6.0 | 337.0 |
05 | 7.0 | 0.0 | 0.0 | 6.0 | 1.0 | 0.0 | 0.0 | 9.0 | 0.0 | 0.0 | 0.0 | 7.0 | 23.0 | 4.0 | 8.0 | 431.0 |
06 | 3.0 | 11.0 | 17.0 | 0.0 | 1.0 | 1.0 | 1.0 | 1.0 | 3.0 | 1.0 | 2.0 | 2.0 | 24.0 | 117.0 | 296.0 | 16.0 |
07 | 22.0 | 1.0 | 0.0 | 8.0 | 90.0 | 6.0 | 2.0 | 32.0 | 191.0 | 9.0 | 5.0 | 111.0 | 13.0 | 1.0 | 0.0 | 5.0 |
08 | 156.0 | 17.0 | 49.0 | 94.0 | 6.0 | 2.0 | 0.0 | 9.0 | 2.0 | 1.0 | 2.0 | 2.0 | 24.0 | 30.0 | 33.0 | 69.0 |
09 | 119.0 | 11.0 | 47.0 | 11.0 | 42.0 | 2.0 | 0.0 | 6.0 | 56.0 | 2.0 | 14.0 | 12.0 | 69.0 | 52.0 | 33.0 | 20.0 |
10 | 7.0 | 3.0 | 1.0 | 275.0 | 2.0 | 10.0 | 0.0 | 55.0 | 2.0 | 4.0 | 4.0 | 84.0 | 1.0 | 0.0 | 1.0 | 47.0 |
11 | 0.0 | 1.0 | 4.0 | 7.0 | 1.0 | 1.0 | 7.0 | 8.0 | 2.0 | 0.0 | 1.0 | 3.0 | 1.0 | 29.0 | 334.0 | 97.0 |
12 | 0.0 | 3.0 | 1.0 | 0.0 | 0.0 | 18.0 | 4.0 | 9.0 | 9.0 | 196.0 | 44.0 | 97.0 | 8.0 | 77.0 | 13.0 | 17.0 |
13 | 8.0 | 2.0 | 2.0 | 5.0 | 188.0 | 19.0 | 5.0 | 82.0 | 34.0 | 10.0 | 10.0 | 8.0 | 72.0 | 7.0 | 7.0 | 37.0 |
14 | 154.0 | 34.0 | 77.0 | 37.0 | 17.0 | 6.0 | 4.0 | 11.0 | 9.0 | 4.0 | 6.0 | 5.0 | 67.0 | 16.0 | 26.0 | 23.0 |
15 | 198.0 | 7.0 | 20.0 | 22.0 | 25.0 | 5.0 | 5.0 | 25.0 | 65.0 | 23.0 | 12.0 | 13.0 | 22.0 | 10.0 | 15.0 | 29.0 |
16 | 41.0 | 32.0 | 54.0 | 183.0 | 2.0 | 11.0 | 4.0 | 28.0 | 15.0 | 16.0 | 8.0 | 13.0 | 5.0 | 23.0 | 18.0 | 43.0 |
17 | 16.0 | 19.0 | 14.0 | 14.0 | 25.0 | 15.0 | 9.0 | 33.0 | 18.0 | 21.0 | 24.0 | 21.0 | 44.0 | 41.0 | 91.0 | 91.0 |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | -2.576 | 0.062 | -0.482 | -0.78 | -1.32 | 0.94 | -1.014 | 0.412 | -4.393 | 0.793 | -0.338 | -0.384 | -1.762 | 1.163 | 0.091 | 0.0 |
02 | -3.119 | -1.106 | -4.393 | -1.968 | -0.713 | 1.674 | -1.762 | 1.112 | -2.226 | 0.703 | -1.014 | -1.207 | -1.207 | 0.94 | -1.968 | -0.431 |
03 | -1.32 | -3.119 | -4.393 | -0.482 | 0.703 | -0.713 | -3.119 | 2.04 | -1.762 | -3.119 | -2.226 | -1.014 | 0.148 | -2.226 | -2.226 | 1.012 |
04 | -1.592 | -3.119 | -3.119 | 1.202 | -2.576 | -4.393 | -4.393 | -0.535 | -4.393 | -4.393 | -4.393 | -1.447 | -1.762 | -1.207 | -1.592 | 2.375 |
05 | -1.447 | -4.393 | -4.393 | -1.592 | -3.119 | -4.393 | -4.393 | -1.207 | -4.393 | -4.393 | -4.393 | -1.447 | -0.294 | -1.968 | -1.32 | 2.621 |
06 | -2.226 | -1.014 | -0.591 | -4.393 | -3.119 | -3.119 | -3.119 | -3.119 | -2.226 | -3.119 | -2.576 | -2.576 | -0.252 | 1.319 | 2.245 | -0.65 |
07 | -0.338 | -3.119 | -4.393 | -1.32 | 1.058 | -1.592 | -2.576 | 0.031 | 1.808 | -1.207 | -1.762 | 1.267 | -0.852 | -3.119 | -4.393 | -1.762 |
08 | 1.606 | -0.591 | 0.453 | 1.101 | -1.592 | -2.576 | -4.393 | -1.207 | -2.576 | -3.119 | -2.576 | -2.576 | -0.252 | -0.032 | 0.062 | 0.793 |
09 | 1.336 | -1.014 | 0.412 | -1.014 | 0.3 | -2.576 | -4.393 | -1.592 | 0.586 | -2.576 | -0.78 | -0.93 | 0.793 | 0.512 | 0.062 | -0.431 |
10 | -1.447 | -2.226 | -3.119 | 2.172 | -2.576 | -1.106 | -4.393 | 0.568 | -2.576 | -1.968 | -1.968 | 0.989 | -3.119 | -4.393 | -3.119 | 0.412 |
11 | -4.393 | -3.119 | -1.968 | -1.447 | -3.119 | -3.119 | -1.447 | -1.32 | -2.576 | -4.393 | -3.119 | -2.226 | -3.119 | -0.066 | 2.366 | 1.132 |
12 | -4.393 | -2.226 | -3.119 | -4.393 | -4.393 | -0.535 | -1.968 | -1.207 | -1.207 | 1.834 | 0.347 | 1.132 | -1.32 | 0.902 | -0.852 | -0.591 |
13 | -1.32 | -2.576 | -2.576 | -1.762 | 1.792 | -0.482 | -1.762 | 0.965 | 0.091 | -1.106 | -1.106 | -1.32 | 0.836 | -1.447 | -1.447 | 0.175 |
14 | 1.593 | 0.091 | 0.902 | 0.175 | -0.591 | -1.592 | -1.968 | -1.014 | -1.207 | -1.968 | -1.592 | -1.762 | 0.764 | -0.65 | -0.174 | -0.294 |
15 | 1.844 | -1.447 | -0.431 | -0.338 | -0.212 | -1.762 | -1.762 | -0.212 | 0.734 | -0.294 | -0.93 | -0.852 | -0.338 | -1.106 | -0.713 | -0.066 |
16 | 0.277 | 0.031 | 0.55 | 1.765 | -2.576 | -1.014 | -1.968 | -0.1 | -0.713 | -0.65 | -1.32 | -0.852 | -1.762 | -0.294 | -0.535 | 0.324 |
17 | -0.65 | -0.482 | -0.78 | -0.78 | -0.212 | -0.713 | -1.207 | 0.062 | -0.535 | -0.384 | -0.252 | -0.384 | 0.347 | 0.277 | 1.069 | 1.069 |