Transcription factor | OTX2 (GeneCards) | ||||||||
Model | OTX2_HUMAN.H11DI.0.A | ||||||||
Model type | Dinucleotide PWM | ||||||||
LOGO | |||||||||
LOGO (reverse complement) | |||||||||
Data source | ChIP-Seq | ||||||||
Model release | HOCOMOCOv11 | ||||||||
Model length | 14 | ||||||||
Quality | A | ||||||||
Motif rank | 0 | ||||||||
Consensus | ndddRGGATTAdvn | ||||||||
Best auROC (human) | 0.879 | ||||||||
Best auROC (mouse) | 0.92 | ||||||||
Peak sets in benchmark (human) | 5 | ||||||||
Peak sets in benchmark (mouse) | 18 | ||||||||
Aligned words | 500 | ||||||||
TF family | Paired-related HD factors {3.1.3} | ||||||||
TF subfamily | OTX {3.1.3.17} | ||||||||
HGNC | HGNC:8522 | ||||||||
EntrezGene | GeneID:5015 (SSTAR profile) | ||||||||
UniProt ID | OTX2_HUMAN | ||||||||
UniProt AC | P32243 (TFClass) | ||||||||
Comment | |||||||||
Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
Standard thresholds |
| ||||||||
GTEx tissue expression atlas | OTX2 expression | ||||||||
ReMap ChIP-seq dataset list | OTX2 datasets | ||||||||
Motifs in JASPAR |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 43.0 | 10.0 | 53.0 | 12.0 | 43.0 | 11.0 | 12.0 | 21.0 | 23.0 | 31.0 | 44.0 | 17.0 | 71.0 | 18.0 | 58.0 | 33.0 |
02 | 100.0 | 15.0 | 48.0 | 17.0 | 31.0 | 7.0 | 9.0 | 23.0 | 50.0 | 38.0 | 57.0 | 22.0 | 21.0 | 12.0 | 32.0 | 18.0 |
03 | 85.0 | 11.0 | 86.0 | 20.0 | 21.0 | 8.0 | 9.0 | 34.0 | 56.0 | 17.0 | 59.0 | 14.0 | 5.0 | 17.0 | 42.0 | 16.0 |
04 | 71.0 | 8.0 | 84.0 | 4.0 | 31.0 | 5.0 | 11.0 | 6.0 | 68.0 | 17.0 | 101.0 | 10.0 | 20.0 | 6.0 | 53.0 | 5.0 |
05 | 23.0 | 2.0 | 165.0 | 0.0 | 19.0 | 1.0 | 15.0 | 1.0 | 63.0 | 4.0 | 179.0 | 3.0 | 3.0 | 0.0 | 22.0 | 0.0 |
06 | 0.0 | 1.0 | 106.0 | 1.0 | 0.0 | 1.0 | 6.0 | 0.0 | 11.0 | 0.0 | 370.0 | 0.0 | 0.0 | 0.0 | 4.0 | 0.0 |
07 | 9.0 | 2.0 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 0.0 | 409.0 | 68.0 | 4.0 | 5.0 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 1.0 | 0.0 | 420.0 | 0.0 | 0.0 | 0.0 | 70.0 | 0.0 | 0.0 | 0.0 | 4.0 | 0.0 | 0.0 | 0.0 | 5.0 |
09 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 499.0 |
10 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 412.0 | 2.0 | 5.0 | 81.0 |
11 | 162.0 | 39.0 | 173.0 | 38.0 | 1.0 | 1.0 | 0.0 | 0.0 | 1.0 | 0.0 | 3.0 | 1.0 | 34.0 | 4.0 | 35.0 | 8.0 |
12 | 63.0 | 53.0 | 73.0 | 9.0 | 20.0 | 18.0 | 1.0 | 5.0 | 33.0 | 83.0 | 64.0 | 31.0 | 1.0 | 27.0 | 14.0 | 5.0 |
13 | 29.0 | 18.0 | 61.0 | 9.0 | 78.0 | 32.0 | 9.0 | 62.0 | 48.0 | 35.0 | 41.0 | 28.0 | 7.0 | 7.0 | 21.0 | 15.0 |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 0.316 | -1.114 | 0.523 | -0.938 | 0.316 | -1.022 | -0.938 | -0.392 | -0.302 | -0.008 | 0.339 | -0.599 | 0.814 | -0.543 | 0.613 | 0.054 |
02 | 1.155 | -0.721 | 0.425 | -0.599 | -0.008 | -1.454 | -1.215 | -0.302 | 0.465 | 0.193 | 0.595 | -0.346 | -0.392 | -0.938 | 0.023 | -0.543 |
03 | 0.993 | -1.022 | 1.004 | -0.439 | -0.392 | -1.328 | -1.215 | 0.083 | 0.578 | -0.599 | 0.63 | -0.788 | -1.77 | -0.599 | 0.293 | -0.658 |
04 | 0.814 | -1.328 | 0.981 | -1.975 | -0.008 | -1.77 | -1.022 | -1.6 | 0.771 | -0.599 | 1.165 | -1.114 | -0.439 | -1.6 | 0.523 | -1.77 |
05 | -0.302 | -2.584 | 1.654 | -4.4 | -0.49 | -3.126 | -0.721 | -3.126 | 0.695 | -1.975 | 1.735 | -2.234 | -2.234 | -4.4 | -0.346 | -4.4 |
06 | -4.4 | -3.126 | 1.213 | -3.126 | -4.4 | -3.126 | -1.6 | -4.4 | -1.022 | -4.4 | 2.46 | -4.4 | -4.4 | -4.4 | -1.975 | -4.4 |
07 | -1.215 | -2.584 | -4.4 | -4.4 | -2.584 | -4.4 | -4.4 | -4.4 | 2.56 | 0.771 | -1.975 | -1.77 | -3.126 | -4.4 | -4.4 | -4.4 |
08 | -4.4 | -3.126 | -4.4 | 2.587 | -4.4 | -4.4 | -4.4 | 0.8 | -4.4 | -4.4 | -4.4 | -1.975 | -4.4 | -4.4 | -4.4 | -1.77 |
09 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -3.126 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | 2.759 |
10 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | 2.568 | -2.584 | -1.77 | 0.945 |
11 | 1.636 | 0.219 | 1.701 | 0.193 | -3.126 | -3.126 | -4.4 | -4.4 | -3.126 | -4.4 | -2.234 | -3.126 | 0.083 | -1.975 | 0.112 | -1.328 |
12 | 0.695 | 0.523 | 0.841 | -1.215 | -0.439 | -0.543 | -3.126 | -1.77 | 0.054 | 0.969 | 0.711 | -0.008 | -3.126 | -0.144 | -0.788 | -1.77 |
13 | -0.074 | -0.543 | 0.663 | -1.215 | 0.907 | 0.023 | -1.215 | 0.679 | 0.425 | 0.112 | 0.269 | -0.108 | -1.454 | -1.454 | -0.392 | -0.721 |