Model info
| Transcription factor | AIRE (GeneCards) | ||||||||
| Model | AIRE_HUMAN.H11MO.0.C | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | Integrative | ||||||||
| Model release | HOCOMOCOv9 | ||||||||
| Model length | 18 | ||||||||
| Quality | C | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | hnnGGWWnddWWGGdbWh | ||||||||
| Best auROC (human) | |||||||||
| Best auROC (mouse) | |||||||||
| Peak sets in benchmark (human) | |||||||||
| Peak sets in benchmark (mouse) | |||||||||
| Aligned words | 41 | ||||||||
| TF family | AIRE {5.3.1} | ||||||||
| TF subfamily | AIRE {5.3.1.0.1} | ||||||||
| HGNC | HGNC:360 | ||||||||
| EntrezGene | GeneID:326 (SSTAR profile) | ||||||||
| UniProt ID | AIRE_HUMAN | ||||||||
| UniProt AC | O43918 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | AIRE expression | ||||||||
| ReMap ChIP-seq dataset list | AIRE datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 16.429 | 10.796 | 5.163 | 8.918 |
| 02 | 7.51 | 7.51 | 5.633 | 20.653 |
| 03 | 5.633 | 5.633 | 8.449 | 21.592 |
| 04 | 1.878 | 0.0 | 36.612 | 2.816 |
| 05 | 0.0 | 0.0 | 33.796 | 7.51 |
| 06 | 13.143 | 1.878 | 0.939 | 25.347 |
| 07 | 15.959 | 3.755 | 0.939 | 20.653 |
| 08 | 15.02 | 5.633 | 5.633 | 15.02 |
| 09 | 14.082 | 2.816 | 5.633 | 18.776 |
| 10 | 21.592 | 3.755 | 5.633 | 10.327 |
| 11 | 15.959 | 1.878 | 2.816 | 20.653 |
| 12 | 9.388 | 5.633 | 2.816 | 23.469 |
| 13 | 0.0 | 0.939 | 36.612 | 3.755 |
| 14 | 0.0 | 0.0 | 40.367 | 0.939 |
| 15 | 9.388 | 3.755 | 10.327 | 17.837 |
| 16 | 2.816 | 7.51 | 7.51 | 23.469 |
| 17 | 18.776 | 0.939 | 6.571 | 15.02 |
| 18 | 16.663 | 11.031 | 4.459 | 9.153 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.433 | 0.041 | -0.614 | -0.134 |
| 02 | -0.288 | -0.288 | -0.54 | 0.651 |
| 03 | -0.54 | -0.54 | -0.182 | 0.694 |
| 04 | -1.389 | -2.493 | 1.205 | -1.1 |
| 05 | -2.493 | -2.493 | 1.127 | -0.288 |
| 06 | 0.223 | -1.389 | -1.796 | 0.848 |
| 07 | 0.406 | -0.877 | -1.796 | 0.651 |
| 08 | 0.349 | -0.54 | -0.54 | 0.349 |
| 09 | 0.288 | -1.1 | -0.54 | 0.56 |
| 10 | 0.694 | -0.877 | -0.54 | 0.0 |
| 11 | 0.406 | -1.389 | -1.1 | 0.651 |
| 12 | -0.087 | -0.54 | -1.1 | 0.774 |
| 13 | -2.493 | -1.796 | 1.205 | -0.877 |
| 14 | -2.493 | -2.493 | 1.3 | -1.796 |
| 15 | -0.087 | -0.877 | 0.0 | 0.511 |
| 16 | -1.1 | -0.288 | -0.288 | 0.774 |
| 17 | 0.56 | -1.796 | -0.406 | 0.349 |
| 18 | 0.447 | 0.061 | -0.737 | -0.11 |