CREB1_HUMAN.H11DI.0.A motif - HOmo sapiens COmprehensive MOdel COllection

Transcription factor

CREB1
(GeneCards)

Model

CREB1_HUMAN.H11DI.0.A

Model type

Dinucleotide PWM

LOGO

LOGO (reverse complement)

Data source

ChIP-Seq

Model release

HOCOMOCOv10

Model length

Quality

Motif rank

Consensus

nhbbbbbnbnnndRTGAYGYvRn

Best auROC (human)

0.954

Best auROC (mouse)

0.907

Peak sets in benchmark (human)

Peak sets in benchmark (mouse)

Aligned words

508

TF family

CREB-related factors {1.1.7}

TF subfamily

CREB-like factors {1.1.7.1}

HGNC

HGNC:2345

EntrezGene

GeneID:1385
(SSTAR profile)

UniProt ID

CREB1_HUMAN

UniProt AC

P16220
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	6.38901
0.0005	8.045760000000001
0.0001	11.385810000000001

GTEx tissue expression atlas

CREB1 expression

ReMap ChIP-seq dataset list

CREB1 datasets

Motifs in JASPAR

MA0018.1 (CREB1; Homo sapiens)

MA0018.2 (CREB1; Mus musculus/Rattus norvegicus/Homo sapiens)

MA0018.3 (CREB1; Homo sapiens)

PCM

	AA	AC	AG	AT	CA	CC	CG	CT	GA	GC	GG	GT	TA	TC	TG	TT
01	28.434	20.34	18.042	22.52	24.882	75.834	9.568	19.801	25.035	69.217	26.068	32.705	9.885	44.168	30.758	42.743
02	8.198	19.729	54.273	6.037	32.294	44.295	94.647	38.323	12.642	19.273	32.365	20.156	8.676	32.649	58.929	17.515
03	12.317	16.467	20.207	12.819	16.4	34.612	23.585	41.348	14.596	43.043	130.532	52.043	6.86	20.583	28.641	25.946
04	5.248	19.244	16.003	9.677	20.056	39.941	34.089	20.619	14.019	132.526	32.591	23.831	0.0	62.352	38.99	30.814
05	12.172	3.477	17.771	5.902	23.364	38.853	171.693	20.153	16.559	41.268	41.325	22.521	11.927	14.128	27.286	31.6
06	13.747	18.676	26.87	4.729	19.319	37.015	28.626	12.766	15.239	177.716	41.002	24.118	9.902	23.188	29.558	17.529
07	11.421	15.701	21.7	9.386	76.602	51.256	89.023	39.714	16.639	44.877	50.015	14.525	2.574	16.967	28.214	11.387
08	16.193	29.483	42.216	19.342	19.566	53.298	27.28	28.657	26.315	88.59	51.79	22.257	3.91	35.487	17.655	17.961
09	16.379	12.404	29.71	7.491	49.636	62.08	56.812	38.331	33.333	38.301	43.098	24.21	11.759	23.918	39.975	12.564
10	24.517	32.88	40.964	12.746	34.922	42.045	24.123	35.614	23.517	58.075	62.991	25.011	15.525	12.756	22.929	31.386
11	23.115	27.492	26.439	21.435	19.024	64.354	9.469	52.908	36.832	50.443	32.083	31.649	9.592	30.518	26.591	38.056
12	40.363	9.257	29.859	9.084	39.397	26.897	58.03	48.483	15.714	9.471	35.81	33.587	24.71	9.577	76.776	32.984
13	53.042	7.612	54.968	4.563	21.233	7.527	24.396	2.046	102.737	32.717	62.967	2.054	29.516	23.07	69.028	2.524
14	3.841	5.343	4.066	193.279	1.072	4.712	1.09	64.053	1.881	6.247	0.0	203.232	0.0	0.0	0.0	11.187
15	0.0	0.0	6.793	0.0	0.0	0.947	14.555	0.799	0.0	0.788	4.368	0.0	3.472	0.0	462.166	6.111
16	3.472	0.0	0.0	0.0	0.788	0.0	0.947	0.0	453.939	1.688	26.44	5.816	5.806	1.104	0.0	0.0
17	2.488	347.69	27.36	86.467	0.0	1.971	0.0	0.821	1.104	23.902	0.0	2.38	0.0	5.816	0.0	0.0
18	0.0	0.0	3.592	0.0	22.046	21.657	329.813	5.864	1.552	2.358	20.899	2.552	0.849	6.594	78.899	3.325
19	0.0	3.509	5.835	15.103	3.46	2.673	1.094	23.382	36.677	91.685	15.499	289.342	2.269	0.776	0.0	8.696
20	10.378	23.984	3.784	4.261	60.15	15.301	11.203	11.99	10.199	8.229	2.906	1.094	56.127	214.167	35.691	30.537
21	66.196	19.465	39.972	11.22	213.451	9.826	10.873	27.531	21.177	8.333	17.25	6.824	14.544	1.161	20.859	11.317
22	53.326	98.144	78.767	85.132	12.899	9.922	11.522	4.442	15.279	38.559	25.108	10.008	9.162	21.712	11.073	14.945

PWM

	AA	AC	AG	AT	CA	CC	CG	CT	GA	GC	GG	GT	TA	TC	TG	TT
01	-0.093	-0.423	-0.54	-0.323	-0.225	0.879	-1.156	-0.449	-0.219	0.788	-0.179	0.045	-1.125	0.342	-0.016	0.31
02	-1.304	-0.453	0.547	-1.594	0.032	0.345	1.1	0.202	-0.887	-0.476	0.035	-0.432	-1.25	0.043	0.629	-0.569
03	-0.912	-0.63	-0.429	-0.874	-0.634	0.101	-0.277	0.277	-0.747	0.317	1.42	0.505	-1.474	-0.411	-0.086	-0.183
04	-1.725	-0.477	-0.658	-1.145	-0.437	0.243	0.086	-0.409	-0.787	1.435	0.041	-0.267	-4.4	0.685	0.219	-0.014
05	-0.924	-2.102	-0.555	-1.615	-0.287	0.215	1.694	-0.432	-0.624	0.275	0.276	-0.323	-0.944	-0.779	-0.134	0.011
06	-0.806	-0.507	-0.149	-1.822	-0.473	0.167	-0.087	-0.878	-0.705	1.728	0.269	-0.255	-1.123	-0.294	-0.055	-0.569
07	-0.985	-0.676	-0.359	-1.175	0.889	0.49	1.039	0.237	-0.62	0.358	0.466	-0.752	-2.368	-0.6	-0.101	-0.988
08	-0.646	-0.057	0.298	-0.472	-0.461	0.529	-0.134	-0.085	-0.17	1.034	0.5	-0.334	-1.996	0.126	-0.562	-0.545
09	-0.635	-0.906	-0.05	-1.39	0.458	0.68	0.592	0.202	0.064	0.201	0.318	-0.252	-0.957	-0.264	0.244	-0.893
10	-0.239	0.05	0.268	-0.879	0.11	0.294	-0.255	0.129	-0.28	0.614	0.695	-0.22	-0.687	-0.878	-0.305	0.004
11	-0.297	-0.126	-0.165	-0.371	-0.488	0.716	-1.166	0.521	0.162	0.474	0.026	0.013	-1.154	-0.023	-0.159	0.195
12	0.253	-1.188	-0.045	-1.206	0.229	-0.148	0.613	0.435	-0.675	-1.166	0.135	0.071	-0.232	-1.155	0.892	0.053
13	0.524	-1.375	0.559	-1.855	-0.381	-1.386	-0.244	-2.565	1.182	0.045	0.694	-2.561	-0.056	-0.299	0.786	-2.385
14	-2.012	-1.708	-1.961	1.812	-3.076	-1.825	-3.063	0.711	-2.635	-1.562	-4.4	1.862	-4.4	-4.4	-4.4	-1.006
15	-4.4	-4.4	-1.483	-4.4	-4.4	-3.165	-0.75	-3.282	-4.4	-3.292	-1.895	-4.4	-2.103	-4.4	2.682	-1.583
16	-2.103	-4.4	-4.4	-4.4	-3.292	-4.4	-3.165	-4.4	2.664	-2.724	-0.165	-1.629	-1.631	-3.054	-4.4	-4.4
17	-2.398	2.398	-0.131	1.01	-4.4	-2.596	-4.4	-3.265	-3.054	-0.264	-4.4	-2.436	-4.4	-1.629	-4.4	-4.4
18	-4.4	-4.4	-2.073	-4.4	-0.344	-0.361	2.345	-1.621	-2.792	-2.444	-0.396	-2.376	-3.241	-1.511	0.919	-2.142
19	-4.4	-2.094	-1.626	-0.714	-2.107	-2.335	-3.061	-0.286	0.158	1.068	-0.689	2.215	-2.477	-3.302	-4.4	-1.248
20	-1.078	-0.261	-2.026	-1.918	0.649	-0.701	-1.004	-0.938	-1.095	-1.301	-2.262	-3.061	0.58	1.914	0.131	-0.023
21	0.744	-0.466	0.243	-1.003	1.911	-1.131	-1.033	-0.125	-0.383	-1.289	-0.584	-1.479	-0.751	-3.017	-0.398	-0.994
22	0.529	1.136	0.917	0.994	-0.868	-1.121	-0.977	-1.879	-0.703	0.208	-0.216	-1.113	-1.198	-0.359	-1.015	-0.724