Model info
| Transcription factor | EGR1 (GeneCards) | ||||||||
| Model | EGR1_HUMAN.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 17 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | vnvdGhGKGGGYGKndv | ||||||||
| Best auROC (human) | 0.989 | ||||||||
| Best auROC (mouse) | 0.981 | ||||||||
| Peak sets in benchmark (human) | 36 | ||||||||
| Peak sets in benchmark (mouse) | 12 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | Three-zinc finger Krüppel-related factors {2.3.1} | ||||||||
| TF subfamily | EGR factors {2.3.1.3} | ||||||||
| HGNC | HGNC:3238 | ||||||||
| EntrezGene | GeneID:1958 (SSTAR profile) | ||||||||
| UniProt ID | EGR1_HUMAN | ||||||||
| UniProt AC | P18146 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | EGR1 expression | ||||||||
| ReMap ChIP-seq dataset list | EGR1 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 116.0 | 124.0 | 205.0 | 55.0 |
| 02 | 160.0 | 64.0 | 159.0 | 117.0 |
| 03 | 139.0 | 90.0 | 230.0 | 41.0 |
| 04 | 118.0 | 56.0 | 177.0 | 149.0 |
| 05 | 56.0 | 15.0 | 404.0 | 25.0 |
| 06 | 118.0 | 253.0 | 23.0 | 106.0 |
| 07 | 28.0 | 17.0 | 435.0 | 20.0 |
| 08 | 16.0 | 2.0 | 205.0 | 277.0 |
| 09 | 46.0 | 1.0 | 446.0 | 7.0 |
| 10 | 8.0 | 2.0 | 479.0 | 11.0 |
| 11 | 12.0 | 16.0 | 465.0 | 7.0 |
| 12 | 110.0 | 238.0 | 2.0 | 150.0 |
| 13 | 44.0 | 5.0 | 421.0 | 30.0 |
| 14 | 55.0 | 11.0 | 348.0 | 86.0 |
| 15 | 169.0 | 64.0 | 203.0 | 64.0 |
| 16 | 156.0 | 41.0 | 228.0 | 75.0 |
| 17 | 132.0 | 91.0 | 218.0 | 59.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.074 | -0.008 | 0.49 | -0.805 |
| 02 | 0.244 | -0.658 | 0.238 | -0.065 |
| 03 | 0.105 | -0.324 | 0.604 | -1.09 |
| 04 | -0.057 | -0.788 | 0.344 | 0.174 |
| 05 | -0.788 | -2.034 | 1.165 | -1.561 |
| 06 | -0.057 | 0.699 | -1.64 | -0.163 |
| 07 | -1.454 | -1.92 | 1.238 | -1.77 |
| 08 | -1.975 | -3.573 | 0.49 | 0.789 |
| 09 | -0.979 | -3.903 | 1.263 | -2.694 |
| 10 | -2.584 | -3.573 | 1.334 | -2.311 |
| 11 | -2.234 | -1.975 | 1.305 | -2.694 |
| 12 | -0.126 | 0.638 | -3.573 | 0.18 |
| 13 | -1.022 | -2.961 | 1.206 | -1.389 |
| 14 | -0.805 | -2.311 | 1.016 | -0.368 |
| 15 | 0.298 | -0.658 | 0.48 | -0.658 |
| 16 | 0.219 | -1.09 | 0.595 | -0.503 |
| 17 | 0.054 | -0.313 | 0.551 | -0.737 |