Model info
| Transcription factor | EGR2 (GeneCards) | ||||||||
| Model | EGR2_HUMAN.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 18 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | RdRdvdShGKGGGhGKdR | ||||||||
| Best auROC (human) | 0.987 | ||||||||
| Best auROC (mouse) | 0.963 | ||||||||
| Peak sets in benchmark (human) | 4 | ||||||||
| Peak sets in benchmark (mouse) | 25 | ||||||||
| Aligned words | 507 | ||||||||
| TF family | Three-zinc finger Krüppel-related factors {2.3.1} | ||||||||
| TF subfamily | EGR factors {2.3.1.3} | ||||||||
| HGNC | HGNC:3239 | ||||||||
| EntrezGene | GeneID:1959 (SSTAR profile) | ||||||||
| UniProt ID | EGR2_HUMAN | ||||||||
| UniProt AC | P11161 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | EGR2 expression | ||||||||
| ReMap ChIP-seq dataset list | EGR2 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 108.0 | 37.0 | 306.0 | 49.0 |
| 02 | 147.0 | 48.0 | 206.0 | 99.0 |
| 03 | 114.0 | 37.0 | 311.0 | 38.0 |
| 04 | 127.0 | 34.0 | 251.0 | 88.0 |
| 05 | 160.0 | 52.0 | 253.0 | 35.0 |
| 06 | 75.0 | 52.0 | 225.0 | 148.0 |
| 07 | 38.0 | 51.0 | 383.0 | 28.0 |
| 08 | 185.0 | 95.0 | 22.0 | 198.0 |
| 09 | 17.0 | 11.0 | 465.0 | 7.0 |
| 10 | 20.0 | 6.0 | 231.0 | 243.0 |
| 11 | 91.0 | 3.0 | 397.0 | 9.0 |
| 12 | 18.0 | 7.0 | 445.0 | 30.0 |
| 13 | 12.0 | 20.0 | 458.0 | 10.0 |
| 14 | 175.0 | 141.0 | 11.0 | 173.0 |
| 15 | 29.0 | 3.0 | 437.0 | 31.0 |
| 16 | 38.0 | 17.0 | 391.0 | 54.0 |
| 17 | 171.0 | 37.0 | 251.0 | 41.0 |
| 18 | 127.0 | 24.0 | 281.0 | 68.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.144 | -1.189 | 0.888 | -0.918 |
| 02 | 0.16 | -0.938 | 0.495 | -0.23 |
| 03 | -0.091 | -1.189 | 0.904 | -1.163 |
| 04 | 0.016 | -1.27 | 0.691 | -0.346 |
| 05 | 0.244 | -0.86 | 0.699 | -1.242 |
| 06 | -0.503 | -0.86 | 0.582 | 0.167 |
| 07 | -1.163 | -0.879 | 1.111 | -1.454 |
| 08 | 0.388 | -0.271 | -1.681 | 0.455 |
| 09 | -1.92 | -2.311 | 1.305 | -2.694 |
| 10 | -1.77 | -2.819 | 0.608 | 0.659 |
| 11 | -0.313 | -3.325 | 1.147 | -2.484 |
| 12 | -1.868 | -2.694 | 1.261 | -1.389 |
| 13 | -2.234 | -1.77 | 1.29 | -2.394 |
| 14 | 0.333 | 0.119 | -2.311 | 0.322 |
| 15 | -1.421 | -3.325 | 1.243 | -1.358 |
| 16 | -1.163 | -1.92 | 1.132 | -0.823 |
| 17 | 0.31 | -1.189 | 0.691 | -1.09 |
| 18 | 0.016 | -1.6 | 0.803 | -0.599 |