Model info
| Transcription factor | EGR2 (GeneCards) | ||||||||
| Model | EGR2_HUMAN.H11MO.1.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 16 | ||||||||
| Quality | A | ||||||||
| Motif rank | 1 | ||||||||
| Consensus | dvdGhGKGGGhGKddv | ||||||||
| Best auROC (human) | 0.988 | ||||||||
| Best auROC (mouse) | 0.98 | ||||||||
| Peak sets in benchmark (human) | 4 | ||||||||
| Peak sets in benchmark (mouse) | 25 | ||||||||
| Aligned words | 505 | ||||||||
| TF family | Three-zinc finger Krüppel-related factors {2.3.1} | ||||||||
| TF subfamily | EGR factors {2.3.1.3} | ||||||||
| HGNC | HGNC:3239 | ||||||||
| EntrezGene | GeneID:1959 (SSTAR profile) | ||||||||
| UniProt ID | EGR2_HUMAN | ||||||||
| UniProt AC | P11161 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | EGR2 expression | ||||||||
| ReMap ChIP-seq dataset list | EGR2 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 97.0 | 72.0 | 228.0 | 101.0 |
| 02 | 140.0 | 86.0 | 226.0 | 46.0 |
| 03 | 94.0 | 50.0 | 186.0 | 168.0 |
| 04 | 31.0 | 33.0 | 423.0 | 11.0 |
| 05 | 122.0 | 182.0 | 29.0 | 165.0 |
| 06 | 3.0 | 9.0 | 483.0 | 3.0 |
| 07 | 6.0 | 5.0 | 173.0 | 314.0 |
| 08 | 81.0 | 2.0 | 405.0 | 10.0 |
| 09 | 12.0 | 5.0 | 460.0 | 21.0 |
| 10 | 12.0 | 9.0 | 475.0 | 2.0 |
| 11 | 160.0 | 178.0 | 6.0 | 154.0 |
| 12 | 16.0 | 3.0 | 454.0 | 25.0 |
| 13 | 34.0 | 14.0 | 355.0 | 95.0 |
| 14 | 149.0 | 47.0 | 229.0 | 73.0 |
| 15 | 110.0 | 40.0 | 261.0 | 87.0 |
| 16 | 94.0 | 82.0 | 257.0 | 65.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.246 | -0.539 | 0.599 | -0.206 |
| 02 | 0.116 | -0.364 | 0.591 | -0.975 |
| 03 | -0.277 | -0.894 | 0.397 | 0.296 |
| 04 | -1.354 | -1.294 | 1.214 | -2.307 |
| 05 | -0.02 | 0.376 | -1.417 | 0.279 |
| 06 | -3.321 | -2.48 | 1.347 | -3.321 |
| 07 | -2.815 | -2.957 | 0.326 | 0.918 |
| 08 | -0.423 | -3.569 | 1.171 | -2.39 |
| 09 | -2.23 | -2.957 | 1.298 | -1.721 |
| 10 | -2.23 | -2.48 | 1.33 | -3.569 |
| 11 | 0.248 | 0.354 | -2.815 | 0.21 |
| 12 | -1.971 | -3.321 | 1.285 | -1.558 |
| 13 | -1.266 | -2.092 | 1.04 | -0.267 |
| 14 | 0.178 | -0.954 | 0.604 | -0.525 |
| 15 | -0.122 | -1.11 | 0.734 | -0.353 |
| 16 | -0.277 | -0.411 | 0.718 | -0.639 |