EGR3_HUMAN.H11MO.0.D motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

EGR3
(GeneCards)

Model

EGR3_HUMAN.H11MO.0.D

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

Integrative

Model release

HOCOMOCOv9

Model length

11

Quality

D

Motif rank

0

Consensus

WRMGTGGGTGb

Best auROC (human)

Best auROC (mouse)

Peak sets in benchmark (human)

Peak sets in benchmark (mouse)

Aligned words

8

TF family

Three-zinc finger Krüppel-related factors {2.3.1}

TF subfamily

EGR factors {2.3.1.3}

HGNC

EntrezGene

GeneID:1960
(SSTAR profile)

UniProt ID

UniProt AC

Q06889
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	4.718505
0.0005	5.358875
0.0001	6.743919999999999

GTEx tissue expression atlas

EGR3 expression

ReMap ChIP-seq dataset list

Motifs in JASPAR

MA0732.1 (EGR3; Homo sapiens)

PCM

	A	C	G	T
01	4.551	0.145	0.145	3.159
02	2.087	0.0	4.754	1.159
03	5.101	1.739	0.0	1.159
04	0.928	0.0	7.072	0.0
05	0.0	0.29	1.449	6.261
06	0.0	0.0	8.0	0.0
07	0.0	0.0	7.072	0.928
08	0.0	0.0	8.0	0.0
09	0.0	3.826	0.0	4.174
10	0.0	0.0	7.072	0.928
11	0.145	1.304	1.304	5.246

PWM

	A	C	G	T
01	0.699	-1.332	-1.332	0.379
02	0.034	-1.578	0.738	-0.406
03	0.802	-0.109	-1.578	-0.406
04	-0.554	-1.578	1.103	-1.578
05	-1.578	-1.135	-0.247	0.99
06	-1.578	-1.578	1.218	-1.578
07	-1.578	-1.578	1.103	-0.554
08	-1.578	-1.578	1.218	-1.578
09	-1.578	0.545	-1.578	0.622
10	-1.578	-1.578	1.103	-0.554
11	-1.332	-0.323	-0.323	0.828