Model info
| Transcription factor | EPAS1 (GeneCards) | ||||||||
| Model | EPAS1_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 9 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | vdACGTGhh | ||||||||
| Best auROC (human) | 0.838 | ||||||||
| Best auROC (mouse) | |||||||||
| Peak sets in benchmark (human) | 24 | ||||||||
| Peak sets in benchmark (mouse) | |||||||||
| Aligned words | 500 | ||||||||
| TF family | PAS domain factors {1.2.5} | ||||||||
| TF subfamily | Ahr-like factors {1.2.5.1} | ||||||||
| HGNC | HGNC:3374 | ||||||||
| EntrezGene | GeneID:2034 (SSTAR profile) | ||||||||
| UniProt ID | EPAS1_HUMAN | ||||||||
| UniProt AC | Q99814 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | EPAS1 expression | ||||||||
| ReMap ChIP-seq dataset list | EPAS1 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 115.0 | 128.0 | 223.0 | 34.0 |
| 02 | 83.0 | 35.0 | 122.0 | 260.0 |
| 03 | 433.0 | 10.0 | 54.0 | 3.0 |
| 04 | 10.0 | 456.0 | 13.0 | 21.0 |
| 05 | 8.0 | 5.0 | 485.0 | 2.0 |
| 06 | 0.0 | 0.0 | 1.0 | 499.0 |
| 07 | 0.0 | 0.0 | 499.0 | 1.0 |
| 08 | 187.0 | 235.0 | 30.0 | 48.0 |
| 09 | 80.0 | 245.0 | 67.0 | 108.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.082 | 0.023 | 0.573 | -1.27 |
| 02 | -0.403 | -1.242 | -0.024 | 0.726 |
| 03 | 1.234 | -2.394 | -0.823 | -3.325 |
| 04 | -2.394 | 1.285 | -2.163 | -1.725 |
| 05 | -2.584 | -2.961 | 1.347 | -3.573 |
| 06 | -4.4 | -4.4 | -3.903 | 1.375 |
| 07 | -4.4 | -4.4 | 1.375 | -3.903 |
| 08 | 0.399 | 0.626 | -1.389 | -0.938 |
| 09 | -0.439 | 0.667 | -0.613 | -0.144 |