FOXC2_HUMAN.H11MO.0.D motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

FOXC2
(GeneCards)

Model

FOXC2_HUMAN.H11MO.0.D

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

Integrative

Model release

HOCOMOCOv9

Model length

15

Quality

D

Motif rank

0

Consensus

KhTTGTTdTGYCAGd

Best auROC (human)

Best auROC (mouse)

Peak sets in benchmark (human)

Peak sets in benchmark (mouse)

Aligned words

5

TF family

Forkhead box (FOX) factors {3.3.1}

TF subfamily

FOXC {3.3.1.3}

HGNC

EntrezGene

GeneID:2303
(SSTAR profile)

UniProt ID

UniProt AC

Q99958
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	5.555175
0.0005	6.292730000000001
0.0001	7.82767

GTEx tissue expression atlas

FOXC2 expression

ReMap ChIP-seq dataset list

Motifs in JASPAR

MA0846.1 (FOXC2; Homo sapiens)

PCM

	A	C	G	T
01	0.268	0.268	3.125	1.339
02	1.071	1.071	0.0	2.857
03	0.0	1.071	0.0	3.929
04	0.0	0.0	0.0	5.0
05	1.071	0.0	3.929	0.0
06	0.0	0.0	0.0	5.0
07	0.0	0.0	0.0	5.0
08	1.071	0.0	1.071	2.857
09	1.786	0.0	0.0	3.214
10	0.0	1.786	3.214	0.0
11	1.071	2.143	0.0	1.786
12	0.0	3.214	0.0	1.786
13	5.0	0.0	0.0	0.0
14	0.0	0.714	4.286	0.0
15	2.411	0.268	1.339	0.982

PWM

	A	C	G	T
01	-0.902	-0.902	0.758	0.053
02	-0.114	-0.114	-1.413	0.679
03	-1.413	-0.114	-1.413	0.964
04	-1.413	-1.413	-1.413	1.185
05	-0.114	-1.413	0.964	-1.413
06	-1.413	-1.413	-1.413	1.185
07	-1.413	-1.413	-1.413	1.185
08	-0.114	-1.413	-0.114	0.679
09	0.281	-1.413	-1.413	0.783
10	-1.413	0.281	0.783	-1.413
11	-0.114	0.432	-1.413	0.281
12	-1.413	0.783	-1.413	0.281
13	1.185	-1.413	-1.413	-1.413
14	-1.413	-0.392	1.043	-1.413
15	0.532	-0.902	0.053	-0.177