Model info
| Transcription factor | FOXO3 (GeneCards) | ||||||||
| Model | FOXO3_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 10 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | bbTGTTTWCh | ||||||||
| Best auROC (human) | 0.668 | ||||||||
| Best auROC (mouse) | 0.947 | ||||||||
| Peak sets in benchmark (human) | 2 | ||||||||
| Peak sets in benchmark (mouse) | 7 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | Forkhead box (FOX) factors {3.3.1} | ||||||||
| TF subfamily | FOXO {3.3.1.15} | ||||||||
| HGNC | HGNC:3821 | ||||||||
| EntrezGene | GeneID:2309 (SSTAR profile) | ||||||||
| UniProt ID | FOXO3_HUMAN | ||||||||
| UniProt AC | O43524 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | FOXO3 expression | ||||||||
| ReMap ChIP-seq dataset list | FOXO3 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 56.0 | 197.0 | 131.0 | 116.0 |
| 02 | 29.0 | 183.0 | 94.0 | 194.0 |
| 03 | 10.0 | 3.0 | 0.0 | 487.0 |
| 04 | 26.0 | 2.0 | 471.0 | 1.0 |
| 05 | 0.0 | 3.0 | 3.0 | 494.0 |
| 06 | 2.0 | 1.0 | 15.0 | 482.0 |
| 07 | 1.0 | 5.0 | 70.0 | 424.0 |
| 08 | 390.0 | 29.0 | 10.0 | 71.0 |
| 09 | 1.0 | 431.0 | 4.0 | 64.0 |
| 10 | 192.0 | 130.0 | 23.0 | 155.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.788 | 0.45 | 0.046 | -0.074 |
| 02 | -1.421 | 0.377 | -0.281 | 0.435 |
| 03 | -2.394 | -3.325 | -4.4 | 1.351 |
| 04 | -1.525 | -3.573 | 1.317 | -3.903 |
| 05 | -4.4 | -3.325 | -3.325 | 1.365 |
| 06 | -3.573 | -3.903 | -2.034 | 1.34 |
| 07 | -3.903 | -2.961 | -0.57 | 1.213 |
| 08 | 1.129 | -1.421 | -2.394 | -0.556 |
| 09 | -3.903 | 1.229 | -3.126 | -0.658 |
| 10 | 0.425 | 0.039 | -1.64 | 0.213 |