GLI2_HUMAN.H11MO.0.D motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

GLI2
(GeneCards)

Model

GLI2_HUMAN.H11MO.0.D

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

Integrative

Model release

HOCOMOCOv9

Model length

11

Quality

D

Motif rank

0

Consensus

STGGGTGGTCb

Best auROC (human)

Best auROC (mouse)

Peak sets in benchmark (human)

Peak sets in benchmark (mouse)

Aligned words

970

TF family

More than 3 adjacent zinc finger factors {2.3.3}

TF subfamily

GLI-like factors {2.3.3.1}

HGNC

EntrezGene

GeneID:2736
(SSTAR profile)

UniProt ID

UniProt AC

P10070
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	-1.9032850000000001
0.0005	-0.522125
0.0001	4.07613

GTEx tissue expression atlas

GLI2 expression

ReMap ChIP-seq dataset list

Motifs in JASPAR

MA0734.1 (GLI2; Homo sapiens)

PCM

	A	C	G	T
01	105.231	162.836	574.351	88.095
02	0.0	0.0	0.0	930.513
03	0.0	0.0	930.513	0.0
04	0.0	0.0	786.124	144.389
05	0.0	0.0	930.513	0.0
06	0.0	0.0	0.0	930.513
07	0.0	0.0	930.513	0.0
08	0.0	0.0	930.513	0.0
09	0.0	0.0	0.0	930.513
10	0.0	930.513	0.0	0.0
11	74.325	343.714	86.807	425.667

PWM

	A	C	G	T
01	-0.784	-0.354	0.899	-0.959
02	-4.921	-4.921	-4.921	1.381
03	-4.921	-4.921	1.381	-4.921
04	-4.921	-4.921	1.213	-0.472
05	-4.921	-4.921	1.381	-4.921
06	-4.921	-4.921	-4.921	1.381
07	-4.921	-4.921	1.381	-4.921
08	-4.921	-4.921	1.381	-4.921
09	-4.921	-4.921	-4.921	1.381
10	-4.921	1.381	-4.921	-4.921
11	-1.126	0.388	-0.974	0.601