GLI3_HUMAN.H11MO.0.B motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

GLI3
(GeneCards)

Model

GLI3_HUMAN.H11MO.0.B

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

Integrative

Model release

HOCOMOCOv9

Model length

11

Quality

B

Motif rank

0

Consensus

nTGGGTGGTYb

Best auROC (human)

Best auROC (mouse)

Peak sets in benchmark (human)

Peak sets in benchmark (mouse)

Aligned words

15

TF family

More than 3 adjacent zinc finger factors {2.3.3}

TF subfamily

GLI-like factors {2.3.3.1}

HGNC

EntrezGene

GeneID:2737
(SSTAR profile)

UniProt ID

UniProt AC

P10071
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	4.676895
0.0005	5.588445
0.0001	7.035285

GTEx tissue expression atlas

GLI3 expression

ReMap ChIP-seq dataset list

Motifs in JASPAR

PCM

	A	C	G	T
01	1.54	4.567	4.463	4.567
02	0.0	1.044	0.0	14.093
03	0.0	0.0	14.093	1.044
04	0.0	1.044	13.049	1.044
05	0.0	0.0	15.137	0.0
06	0.0	0.0	0.0	15.137
07	0.0	0.0	15.137	0.0
08	0.0	0.0	13.049	2.088
09	1.044	0.0	1.044	13.049
10	1.044	9.918	1.044	3.132
11	1.54	5.611	2.584	5.402

PWM

	A	C	G	T
01	-0.699	0.162	0.142	0.162
02	-1.883	-0.952	-1.883	1.197
03	-1.883	-1.883	1.197	-0.952
04	-1.883	-0.952	1.124	-0.952
05	-1.883	-1.883	1.265	-1.883
06	-1.883	-1.883	-1.883	1.265
07	-1.883	-1.883	1.265	-1.883
08	-1.883	-1.883	1.124	-0.478
09	-0.952	-1.883	-0.952	1.124
10	-0.952	0.865	-0.952	-0.158
11	-0.699	0.343	-0.313	0.309