HMGA2_HUMAN.H11MO.0.D motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

HMGA2
(GeneCards)

Model

HMGA2_HUMAN.H11MO.0.D

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

Integrative

Model release

HOCOMOCOv9

Model length

15

Quality

D

Motif rank

0

Consensus

AATAWhSSSSAATAT

Best auROC (human)

Best auROC (mouse)

Peak sets in benchmark (human)

Peak sets in benchmark (mouse)

Aligned words

75

TF family

HMGA factors {8.2.1}

TF subfamily

HMGA2 (HMGI-C) {8.2.1.0.2}

HGNC

EntrezGene

GeneID:8091
(SSTAR profile)

UniProt ID

UniProt AC

P52926
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	4.18141
0.0005	5.21481
0.0001	7.3510100000000005

GTEx tissue expression atlas

HMGA2 expression

ReMap ChIP-seq dataset list

Motifs in JASPAR

PCM

	A	C	G	T
01	71.752	1.241	1.241	1.241
02	54.621	0.0	0.0	20.855
03	11.917	0.0	0.0	63.559
04	44.69	0.0	0.0	30.786
05	39.724	1.986	0.993	32.772
06	12.91	20.855	8.938	32.772
07	0.0	41.71	29.793	3.972
08	1.986	24.828	46.676	1.986
09	0.0	37.738	32.772	4.966
10	1.986	31.779	40.717	0.993
11	71.503	0.0	2.979	0.993
12	59.586	0.993	0.0	14.897
13	1.986	0.993	0.0	72.497
14	59.586	0.0	0.993	14.897
15	1.49	1.49	1.49	71.007

PWM

	A	C	G	T
01	1.295	-2.151	-2.151	-2.151
02	1.027	-2.915	-2.915	0.095
03	-0.428	-2.915	-2.915	1.176
04	0.83	-2.915	-2.915	0.468
05	0.716	-1.872	-2.264	0.529
06	-0.355	0.095	-0.689	0.529
07	-2.915	0.763	0.437	-1.373
08	-1.872	0.261	0.873	-1.872
09	-2.915	0.666	0.529	-1.194
10	-1.872	0.499	0.74	-2.264
11	1.292	-2.915	-1.592	-2.264
12	1.112	-2.264	-2.915	-0.222
13	-1.872	-2.264	-2.915	1.305
14	1.112	-2.915	-2.264	-0.222
15	-2.049	-2.049	-2.049	1.285