We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorIRF3
(GeneCards)
ModelIRF3_HUMAN.H11DI.0.B
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length23
Quality
B
Motif rank
0
ConsensusnvdRRMdRGAAAvnGAAAvndvv
Best auROC (human)0.797
Best auROC (mouse)0.962
Peak sets in benchmark (human)6
Peak sets in benchmark (mouse)21
Aligned words510
TF familyInterferon-regulatory factors {3.5.3}
TF subfamilyIRF-3 {3.5.3.0.3}
HGNCHGNC:6118
EntrezGeneGeneID:3661
(SSTAR profile)
UniProt IDIRF3_HUMAN
UniProt ACQ14653
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 9.612960000000001
0.0005 11.806360000000002
0.0001 16.42471
GTEx tissue expression atlas IRF3 expression
ReMap ChIP-seq dataset list IRF3 datasets
Motifs in JASPAR
MA1418.1 (IRF3; Homo sapiens)
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
0143.031.046.07.035.014.05.014.030.016.044.07.014.017.022.08.0
0247.07.051.017.056.01.014.07.047.05.054.011.016.01.011.08.0
0388.02.074.02.07.02.01.04.092.02.033.03.012.02.025.04.0
04139.02.050.08.04.01.00.03.098.06.020.09.04.01.07.01.0
05205.016.011.013.06.01.00.03.061.06.07.03.07.04.05.05.0
06146.033.059.041.013.03.01.010.012.03.06.02.03.01.011.09.0
0729.07.0121.017.010.014.07.09.018.04.047.08.011.05.042.04.0
0814.00.054.00.018.00.012.00.018.01.0198.00.01.00.037.00.0
0944.00.07.00.01.00.00.00.0267.03.031.00.00.00.00.00.0
10294.00.017.01.03.00.00.00.036.01.00.01.00.00.00.00.0
11320.02.06.05.01.00.00.00.016.01.00.00.02.00.00.00.0
1238.0177.0104.020.00.03.00.00.00.01.04.01.00.05.00.00.0
1313.02.013.010.064.045.015.062.018.011.047.032.04.04.08.05.0
1416.03.078.02.027.01.032.02.05.02.074.02.010.01.097.01.0
1549.01.06.02.03.02.00.02.0230.010.033.08.04.01.01.01.0
16265.010.06.05.012.01.00.01.035.03.02.00.06.00.06.01.0
17276.08.018.016.08.00.00.06.09.03.00.02.02.01.01.03.0
1840.0134.0105.016.04.02.01.05.02.06.05.06.03.07.014.03.0
1915.09.08.017.053.042.02.052.032.022.036.035.07.04.08.011.0
2034.010.052.011.036.015.012.014.012.02.038.02.021.018.056.020.0
2153.08.033.09.025.010.03.07.090.021.037.010.012.07.019.09.0
2293.014.056.017.015.011.05.015.033.020.028.011.05.011.012.07.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
010.6590.3350.726-1.1130.455-0.445-1.43-0.4450.303-0.3150.682-1.113-0.445-0.256-0.003-0.986
020.748-1.1130.829-0.2560.922-2.798-0.445-1.1130.748-1.430.885-0.68-0.315-2.798-0.68-0.986
031.371-2.2491.199-2.249-1.113-2.249-2.798-1.6361.415-2.2490.397-1.896-0.595-2.2490.123-1.636
041.827-2.2490.809-0.986-1.636-2.798-4.114-1.8961.478-1.259-0.096-0.873-1.636-2.798-1.113-2.798
052.214-0.315-0.68-0.518-1.259-2.798-4.114-1.8961.007-1.259-1.113-1.896-1.113-1.636-1.43-1.43
061.8760.3970.9730.612-0.518-1.896-2.798-0.772-0.595-1.896-1.259-2.249-1.896-2.798-0.68-0.873
070.269-1.1131.688-0.256-0.772-0.445-1.113-0.873-0.2-1.6360.748-0.986-0.68-1.430.636-1.636
08-0.445-4.1140.885-4.114-0.2-4.114-0.595-4.114-0.2-2.7982.18-4.114-2.798-4.1140.51-4.114
090.682-4.114-1.113-4.114-2.798-4.114-4.114-4.1142.478-1.8960.335-4.114-4.114-4.114-4.114-4.114
102.574-4.114-0.256-2.798-1.896-4.114-4.114-4.1140.483-2.798-4.114-2.798-4.114-4.114-4.114-4.114
112.659-2.249-1.259-1.43-2.798-4.114-4.114-4.114-0.315-2.798-4.114-4.114-2.249-4.114-4.114-4.114
120.5372.0681.538-0.096-4.114-1.896-4.114-4.114-4.114-2.798-1.636-2.798-4.114-1.43-4.114-4.114
13-0.518-2.249-0.518-0.7721.0540.704-0.3781.023-0.2-0.680.7480.367-1.636-1.636-0.986-1.43
14-0.315-1.8961.251-2.2490.199-2.7980.367-2.249-1.43-2.2491.199-2.249-0.772-2.7981.468-2.798
150.789-2.798-1.259-2.249-1.896-2.249-4.114-2.2492.329-0.7720.397-0.986-1.636-2.798-2.798-2.798
162.471-0.772-1.259-1.43-0.595-2.798-4.114-2.7980.455-1.896-2.249-4.114-1.259-4.114-1.259-2.798
172.511-0.986-0.2-0.315-0.986-4.114-4.114-1.259-0.873-1.896-4.114-2.249-2.249-2.798-2.798-1.896
180.5881.791.547-0.315-1.636-2.249-2.798-1.43-2.249-1.259-1.43-1.259-1.896-1.113-0.445-1.896
19-0.378-0.873-0.986-0.2560.8670.636-2.2490.8480.367-0.0030.4830.455-1.113-1.636-0.986-0.68
200.427-0.7720.848-0.680.483-0.378-0.595-0.445-0.595-2.2490.537-2.249-0.049-0.20.922-0.096
210.867-0.9860.397-0.8730.123-0.772-1.896-1.1131.394-0.0490.51-0.772-0.595-1.113-0.147-0.873
221.426-0.4450.922-0.256-0.378-0.68-1.43-0.3780.397-0.0960.235-0.68-1.43-0.68-0.595-1.113