Model info
| Transcription factor | IRF3 (GeneCards) | ||||||||
| Model | IRF3_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 20 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | dRRRddRAAAvdGRAASnRR | ||||||||
| Best auROC (human) | 0.789 | ||||||||
| Best auROC (mouse) | 0.948 | ||||||||
| Peak sets in benchmark (human) | 6 | ||||||||
| Peak sets in benchmark (mouse) | 21 | ||||||||
| Aligned words | 505 | ||||||||
| TF family | Interferon-regulatory factors {3.5.3} | ||||||||
| TF subfamily | IRF-3 {3.5.3.0.3} | ||||||||
| HGNC | HGNC:6118 | ||||||||
| EntrezGene | GeneID:3661 (SSTAR profile) | ||||||||
| UniProt ID | IRF3_HUMAN | ||||||||
| UniProt AC | Q14653 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | IRF3 expression | ||||||||
| ReMap ChIP-seq dataset list | IRF3 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 150.0 | 39.0 | 257.0 | 54.0 |
| 02 | 302.0 | 22.0 | 150.0 | 26.0 |
| 03 | 339.0 | 33.0 | 107.0 | 21.0 |
| 04 | 360.0 | 37.0 | 55.0 | 48.0 |
| 05 | 153.0 | 54.0 | 228.0 | 65.0 |
| 06 | 112.0 | 27.0 | 279.0 | 82.0 |
| 07 | 101.0 | 27.0 | 366.0 | 6.0 |
| 08 | 410.0 | 9.0 | 74.0 | 7.0 |
| 09 | 408.0 | 18.0 | 63.0 | 11.0 |
| 10 | 450.0 | 8.0 | 15.0 | 27.0 |
| 11 | 112.0 | 131.0 | 223.0 | 34.0 |
| 12 | 146.0 | 44.0 | 201.0 | 109.0 |
| 13 | 100.0 | 3.0 | 392.0 | 5.0 |
| 14 | 337.0 | 12.0 | 145.0 | 6.0 |
| 15 | 440.0 | 18.0 | 36.0 | 6.0 |
| 16 | 471.0 | 2.0 | 20.0 | 7.0 |
| 17 | 48.0 | 157.0 | 274.0 | 21.0 |
| 18 | 133.0 | 71.0 | 137.0 | 159.0 |
| 19 | 114.0 | 61.0 | 293.0 | 32.0 |
| 20 | 341.0 | 35.0 | 89.0 | 35.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.18 | -1.138 | 0.714 | -0.823 |
| 02 | 0.875 | -1.681 | 0.18 | -1.525 |
| 03 | 0.99 | -1.298 | -0.153 | -1.725 |
| 04 | 1.05 | -1.189 | -0.805 | -0.938 |
| 05 | 0.2 | -0.823 | 0.595 | -0.643 |
| 06 | -0.108 | -1.489 | 0.796 | -0.415 |
| 07 | -0.21 | -1.489 | 1.066 | -2.819 |
| 08 | 1.179 | -2.484 | -0.516 | -2.694 |
| 09 | 1.174 | -1.868 | -0.673 | -2.311 |
| 10 | 1.272 | -2.584 | -2.034 | -1.489 |
| 11 | -0.108 | 0.046 | 0.573 | -1.27 |
| 12 | 0.154 | -1.022 | 0.47 | -0.135 |
| 13 | -0.22 | -3.325 | 1.135 | -2.961 |
| 14 | 0.984 | -2.234 | 0.147 | -2.819 |
| 15 | 1.25 | -1.868 | -1.215 | -2.819 |
| 16 | 1.317 | -3.573 | -1.77 | -2.694 |
| 17 | -0.938 | 0.225 | 0.778 | -1.725 |
| 18 | 0.061 | -0.556 | 0.091 | 0.238 |
| 19 | -0.091 | -0.705 | 0.845 | -1.328 |
| 20 | 0.996 | -1.242 | -0.335 | -1.242 |