Model info
| Transcription factor | ISL2 (GeneCards) | ||||||||
| Model | ISL2_HUMAN.H11MO.0.D | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | HT-SELEX | ||||||||
| Model release | HOCOMOCOv10 | ||||||||
| Model length | 11 | ||||||||
| Quality | D | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | hnbTAAKTGvh | ||||||||
| Best auROC (human) | |||||||||
| Best auROC (mouse) | |||||||||
| Peak sets in benchmark (human) | |||||||||
| Peak sets in benchmark (mouse) | |||||||||
| Aligned words | 16988 | ||||||||
| TF family | HD-LIM factors {3.1.5} | ||||||||
| TF subfamily | ISL {3.1.5.1} | ||||||||
| HGNC | HGNC:18524 | ||||||||
| EntrezGene | GeneID:64843 (SSTAR profile) | ||||||||
| UniProt ID | ISL2_HUMAN | ||||||||
| UniProt AC | Q96A47 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | ISL2 expression | ||||||||
| ReMap ChIP-seq dataset list | ISL2 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 3122.5 | 6522.5 | 2376.5 | 4921.5 |
| 02 | 5167.75 | 3043.75 | 5902.75 | 2828.75 |
| 03 | 1281.0 | 6095.0 | 1329.0 | 8238.0 |
| 04 | 710.25 | 378.25 | 415.25 | 15439.25 |
| 05 | 16697.0 | 6.0 | 227.0 | 13.0 |
| 06 | 16850.0 | 10.0 | 56.0 | 27.0 |
| 07 | 66.5 | 5.5 | 7103.5 | 9767.5 |
| 08 | 100.0 | 23.0 | 2980.0 | 13840.0 |
| 09 | 1754.5 | 187.5 | 14863.5 | 137.5 |
| 10 | 3834.25 | 8659.25 | 3531.25 | 918.25 |
| 11 | 4642.0 | 3355.0 | 1383.0 | 7563.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.305 | 0.431 | -0.577 | 0.15 |
| 02 | 0.199 | -0.33 | 0.332 | -0.403 |
| 03 | -1.195 | 0.364 | -1.158 | 0.665 |
| 04 | -1.783 | -2.41 | -2.317 | 1.293 |
| 05 | 1.371 | -6.22 | -2.916 | -5.615 |
| 06 | 1.38 | -5.831 | -4.284 | -4.97 |
| 07 | -4.119 | -6.281 | 0.517 | 0.835 |
| 08 | -3.723 | -5.116 | -0.351 | 1.184 |
| 09 | -0.881 | -3.105 | 1.255 | -3.411 |
| 10 | -0.1 | 0.715 | -0.182 | -1.527 |
| 11 | 0.092 | -0.233 | -1.118 | 0.579 |