KLF4_MOUSE.H11MO.0.A motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

Model

KLF4_MOUSE.H11MO.0.A

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

ChIP-Seq

Model release

HOCOMOCOv11

Model length

15

Quality

A

Motif rank

0

Consensus

dvvdvWGGGYGKGKM

Best auROC (human)

0.909

Best auROC (mouse)

0.975

Peak sets in benchmark (human)

11

Peak sets in benchmark (mouse)

34

Aligned words

500

TF family

Three-zinc finger Krüppel-related factors {2.3.1}

TF subfamily

Krüppel-like factors {2.3.1.2}

MGI

EntrezGene

GeneID:16600
(SSTAR profile)

UniProt ID

UniProt AC

Q60793
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	4.41481
0.0005	5.28461
0.0001	7.079910000000001

GTEx tissue expression atlas

Klf4 expression

Motifs in JASPAR

MA0039.1 (Klf4; Mus musculus)

MA0039.2 (Klf4; Mus musculus)

MA0039.3 (KLF4; Homo sapiens)

PCM

	A	C	G	T
01	85.0	72.0	171.0	172.0
02	131.0	92.0	235.0	42.0
03	143.0	103.0	210.0	44.0
04	231.0	60.0	146.0	63.0
05	128.0	118.0	235.0	19.0
06	171.0	9.0	79.0	241.0
07	53.0	2.0	443.0	2.0
08	14.0	0.0	446.0	40.0
09	29.0	22.0	442.0	7.0
10	58.0	116.0	8.0	318.0
11	48.0	5.0	439.0	8.0
12	11.0	3.0	217.0	269.0
13	37.0	4.0	408.0	51.0
14	32.0	20.0	361.0	87.0
15	75.0	341.0	35.0	49.0

PWM

	A	C	G	T
01	-0.38	-0.543	0.31	0.316
02	0.046	-0.302	0.626	-1.067
03	0.133	-0.191	0.514	-1.022
04	0.608	-0.721	0.154	-0.673
05	0.023	-0.057	0.626	-1.818
06	0.31	-2.484	-0.452	0.651
07	-0.841	-3.573	1.256	-3.573
08	-2.096	-4.4	1.263	-1.114
09	-1.421	-1.681	1.254	-2.694
10	-0.754	-0.074	-2.584	0.926
11	-0.938	-2.961	1.247	-2.584
12	-2.311	-3.325	0.546	0.76
13	-1.189	-3.126	1.174	-0.879
14	-1.328	-1.77	1.053	-0.357
15	-0.503	0.996	-1.242	-0.918