We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorLEF1
(GeneCards)
ModelLEF1_HUMAN.H11DI.0.A
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length18
Quality
A
Motif rank
0
ConsensusnYYWTTSWdvTKYWdWbn
Best auROC (human)0.912
Best auROC (mouse)
Peak sets in benchmark (human)20
Peak sets in benchmark (mouse)
Aligned words496
TF familyTCF-7-related factors {4.1.3}
TF subfamilyLEF-1 (TCF-1alpha) [1] {4.1.3.0.4}
HGNCHGNC:6551
EntrezGeneGeneID:51176
(SSTAR profile)
UniProt IDLEF1_HUMAN
UniProt ACQ9UJU2
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 11.484110000000001
0.0005 13.24676
0.0001 16.87036
GTEx tissue expression atlas LEF1 expression
ReMap ChIP-seq dataset list LEF1 datasets
Motifs in JASPAR
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
012.033.019.014.08.080.011.047.00.069.022.021.05.0100.034.031.0
021.010.00.04.015.0167.05.095.03.063.011.09.09.080.04.020.0
038.01.00.019.063.015.01.0241.05.01.03.011.036.03.03.086.0
046.01.01.0104.02.00.00.018.00.00.00.07.05.09.06.0337.0
057.00.00.06.01.00.00.09.00.00.00.07.023.04.08.0431.0
063.011.017.00.01.01.01.01.03.01.02.02.024.0117.0296.016.0
0722.01.00.08.090.06.02.032.0191.09.05.0111.013.01.00.05.0
08156.017.049.094.06.02.00.09.02.01.02.02.024.030.033.069.0
09119.011.047.011.042.02.00.06.056.02.014.012.069.052.033.020.0
107.03.01.0275.02.010.00.055.02.04.04.084.01.00.01.047.0
110.01.04.07.01.01.07.08.02.00.01.03.01.029.0334.097.0
120.03.01.00.00.018.04.09.09.0196.044.097.08.077.013.017.0
138.02.02.05.0188.019.05.082.034.010.010.08.072.07.07.037.0
14154.034.077.037.017.06.04.011.09.04.06.05.067.016.026.023.0
15198.07.020.022.025.05.05.025.065.023.012.013.022.010.015.029.0
1641.032.054.0183.02.011.04.028.015.016.08.013.05.023.018.043.0
1716.019.014.014.025.015.09.033.018.021.024.021.044.041.091.091.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
01-2.5760.062-0.482-0.78-1.320.94-1.0140.412-4.3930.793-0.338-0.384-1.7621.1630.0910.0
02-3.119-1.106-4.393-1.968-0.7131.674-1.7621.112-2.2260.703-1.014-1.207-1.2070.94-1.968-0.431
03-1.32-3.119-4.393-0.4820.703-0.713-3.1192.04-1.762-3.119-2.226-1.0140.148-2.226-2.2261.012
04-1.592-3.119-3.1191.202-2.576-4.393-4.393-0.535-4.393-4.393-4.393-1.447-1.762-1.207-1.5922.375
05-1.447-4.393-4.393-1.592-3.119-4.393-4.393-1.207-4.393-4.393-4.393-1.447-0.294-1.968-1.322.621
06-2.226-1.014-0.591-4.393-3.119-3.119-3.119-3.119-2.226-3.119-2.576-2.576-0.2521.3192.245-0.65
07-0.338-3.119-4.393-1.321.058-1.592-2.5760.0311.808-1.207-1.7621.267-0.852-3.119-4.393-1.762
081.606-0.5910.4531.101-1.592-2.576-4.393-1.207-2.576-3.119-2.576-2.576-0.252-0.0320.0620.793
091.336-1.0140.412-1.0140.3-2.576-4.393-1.5920.586-2.576-0.78-0.930.7930.5120.062-0.431
10-1.447-2.226-3.1192.172-2.576-1.106-4.3930.568-2.576-1.968-1.9680.989-3.119-4.393-3.1190.412
11-4.393-3.119-1.968-1.447-3.119-3.119-1.447-1.32-2.576-4.393-3.119-2.226-3.119-0.0662.3661.132
12-4.393-2.226-3.119-4.393-4.393-0.535-1.968-1.207-1.2071.8340.3471.132-1.320.902-0.852-0.591
13-1.32-2.576-2.576-1.7621.792-0.482-1.7620.9650.091-1.106-1.106-1.320.836-1.447-1.4470.175
141.5930.0910.9020.175-0.591-1.592-1.968-1.014-1.207-1.968-1.592-1.7620.764-0.65-0.174-0.294
151.844-1.447-0.431-0.338-0.212-1.762-1.762-0.2120.734-0.294-0.93-0.852-0.338-1.106-0.713-0.066
160.2770.0310.551.765-2.576-1.014-1.968-0.1-0.713-0.65-1.32-0.852-1.762-0.294-0.5350.324
17-0.65-0.482-0.78-0.78-0.212-0.713-1.2070.062-0.535-0.384-0.252-0.3840.3470.2771.0691.069