Model info
| Transcription factor | LEF1 (GeneCards) | ||||||||
| Model | LEF1_HUMAN.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 14 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | bSYTTTSWhnKbhh | ||||||||
| Best auROC (human) | 0.876 | ||||||||
| Best auROC (mouse) | |||||||||
| Peak sets in benchmark (human) | 20 | ||||||||
| Peak sets in benchmark (mouse) | |||||||||
| Aligned words | 456 | ||||||||
| TF family | TCF-7-related factors {4.1.3} | ||||||||
| TF subfamily | LEF-1 (TCF-1alpha) [1] {4.1.3.0.4} | ||||||||
| HGNC | HGNC:6551 | ||||||||
| EntrezGene | GeneID:51176 (SSTAR profile) | ||||||||
| UniProt ID | LEF1_HUMAN | ||||||||
| UniProt AC | Q9UJU2 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | LEF1 expression | ||||||||
| ReMap ChIP-seq dataset list | LEF1 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 35.0 | 119.0 | 125.0 | 177.0 |
| 02 | 15.0 | 290.0 | 84.0 | 67.0 |
| 03 | 8.0 | 323.0 | 6.0 | 119.0 |
| 04 | 56.0 | 21.0 | 9.0 | 370.0 |
| 05 | 1.0 | 63.0 | 16.0 | 376.0 |
| 06 | 1.0 | 6.0 | 15.0 | 434.0 |
| 07 | 20.0 | 194.0 | 237.0 | 5.0 |
| 08 | 208.0 | 63.0 | 7.0 | 178.0 |
| 09 | 127.0 | 76.0 | 72.0 | 181.0 |
| 10 | 130.0 | 87.0 | 92.0 | 147.0 |
| 11 | 19.0 | 59.0 | 68.0 | 310.0 |
| 12 | 18.0 | 142.0 | 175.0 | 121.0 |
| 13 | 53.0 | 210.0 | 41.0 | 152.0 |
| 14 | 143.0 | 101.0 | 47.0 | 165.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.151 | 0.042 | 0.091 | 0.435 |
| 02 | -1.944 | 0.926 | -0.301 | -0.522 |
| 03 | -2.495 | 1.033 | -2.731 | 0.042 |
| 04 | -0.697 | -1.635 | -2.395 | 1.168 |
| 05 | -3.821 | -0.582 | -1.886 | 1.184 |
| 06 | -3.821 | -2.731 | -1.944 | 1.327 |
| 07 | -1.68 | 0.526 | 0.725 | -2.873 |
| 08 | 0.595 | -0.582 | -2.606 | 0.441 |
| 09 | 0.107 | -0.399 | -0.452 | 0.457 |
| 10 | 0.13 | -0.266 | -0.211 | 0.251 |
| 11 | -1.728 | -0.646 | -0.508 | 0.992 |
| 12 | -1.778 | 0.217 | 0.424 | 0.059 |
| 13 | -0.751 | 0.605 | -0.999 | 0.284 |
| 14 | 0.224 | -0.119 | -0.867 | 0.366 |