LHX3_HUMAN.H11MO.0.C motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

LHX3
(GeneCards)

Model

LHX3_HUMAN.H11MO.0.C

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

Integrative

Model release

HOCOMOCOv9

Model length

13

Quality

C

Motif rank

0

Consensus

ddAWTTAATTAdh

Best auROC (human)

Best auROC (mouse)

Peak sets in benchmark (human)

Peak sets in benchmark (mouse)

Aligned words

72

TF family

HD-LIM factors {3.1.5}

TF subfamily

Lhx-3-like factors {3.1.5.4}

HGNC

EntrezGene

GeneID:8022
(SSTAR profile)

UniProt ID

UniProt AC

Q9UBR4
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	5.15886
0.0005	6.23021
0.0001	8.289885000000002

GTEx tissue expression atlas

LHX3 expression

ReMap ChIP-seq dataset list

Motifs in JASPAR

MA0135.1 (Lhx3; Mus musculus)

PCM

	A	C	G	T
01	39.219	5.201	13.095	14.485
02	37.52	2.953	15.362	16.165
03	57.229	6.837	7.343	0.591
04	42.292	1.519	11.268	16.921
05	0.759	0.506	1.519	69.216
06	0.0	0.0	0.759	71.241
07	72.0	0.0	0.0	0.0
08	71.241	0.0	0.759	0.0
09	0.0	0.0	0.0	72.0
10	1.562	0.759	1.266	68.413
11	67.95	0.0	1.519	2.531
12	33.764	6.793	23.761	7.681
13	12.028	18.571	11.437	29.964

PWM

	A	C	G	T
01	0.748	-1.112	-0.297	-0.204
02	0.705	-1.556	-0.149	-0.101
03	1.117	-0.88	-0.818	-2.441
04	0.821	-1.997	-0.435	-0.058
05	-2.345	-2.494	-1.997	1.304
06	-2.881	-2.881	-2.345	1.333
07	1.343	-2.881	-2.881	-2.881
08	1.333	-2.881	-2.345	-2.881
09	-2.881	-2.881	-2.881	1.343
10	-1.98	-2.345	-2.1	1.293
11	1.286	-2.881	-1.997	-1.667
12	0.603	-0.886	0.264	-0.779
13	-0.376	0.03	-0.422	0.487