We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorMEF2C
(GeneCards)
ModelMEF2C_HUMAN.H11DI.0.A
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length15
Quality
A
Motif rank
0
ConsensusnddYTATTTWWRdhn
Best auROC (human)0.963
Best auROC (mouse)0.886
Peak sets in benchmark (human)6
Peak sets in benchmark (mouse)9
Aligned words496
TF familyRegulators of differentiation {5.1.1}
TF subfamilyMEF-2 {5.1.1.1}
HGNCHGNC:6996
EntrezGeneGeneID:4208
(SSTAR profile)
UniProt IDMEF2C_HUMAN
UniProt ACQ06413
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 10.98536
0.0005 12.79581
0.0001 16.53621
GTEx tissue expression atlas MEF2C expression
ReMap ChIP-seq dataset list MEF2C datasets
Motifs in JASPAR
MA0497.1 (MEF2C; Homo sapiens)
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
0139.02.056.035.029.09.08.040.036.014.034.050.023.07.043.071.0
0210.021.064.032.08.01.08.015.017.016.069.039.017.013.069.097.0
033.037.03.09.03.029.01.018.05.0132.015.058.08.0116.010.049.0
042.03.00.014.01.011.04.0298.00.02.00.027.01.09.00.0124.0
052.01.01.00.023.01.00.01.02.02.00.00.0433.04.018.08.0
0622.05.03.0430.02.02.01.03.01.00.02.016.00.00.00.09.0
075.01.00.019.00.01.00.06.01.01.00.04.042.04.02.0410.0
081.02.02.043.00.02.00.05.00.01.00.01.026.024.04.0385.0
097.01.00.019.03.04.02.020.01.02.02.01.079.037.04.0314.0
108.07.05.070.04.06.03.031.01.03.01.03.040.023.042.0249.0
1121.01.029.02.030.00.09.00.021.00.029.01.0224.06.0118.05.0
1280.015.0166.035.02.01.02.02.018.019.0115.033.03.00.03.02.0
1350.035.05.013.010.013.00.012.0117.0100.030.039.020.035.010.07.0
1483.040.042.032.053.055.015.060.015.011.07.012.015.014.010.032.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
010.227-2.5760.5860.12-0.066-1.207-1.320.2520.148-0.780.0910.473-0.294-1.4470.3240.822
02-1.106-0.3840.7190.031-1.32-3.119-1.32-0.713-0.591-0.650.7930.227-0.591-0.8520.7931.132
03-2.2260.175-2.226-1.207-2.226-0.066-3.119-0.535-1.7621.439-0.7130.621-1.321.311-1.1060.453
04-2.576-2.226-4.393-0.78-3.119-1.014-1.9682.252-4.393-2.576-4.393-0.136-3.119-1.207-4.3931.377
05-2.576-3.119-3.119-4.393-0.294-3.119-4.393-3.119-2.576-2.576-4.393-4.3932.625-1.968-0.535-1.32
06-0.338-1.762-2.2262.618-2.576-2.576-3.119-2.226-3.119-4.393-2.576-0.65-4.393-4.393-4.393-1.207
07-1.762-3.119-4.393-0.482-4.393-3.119-4.393-1.592-3.119-3.119-4.393-1.9680.3-1.968-2.5762.571
08-3.119-2.576-2.5760.324-4.393-2.576-4.393-1.762-4.393-3.119-4.393-3.119-0.174-0.252-1.9682.508
09-1.447-3.119-4.393-0.482-2.226-1.968-2.576-0.431-3.119-2.576-2.576-3.1190.9280.175-1.9682.304
10-1.32-1.447-1.7620.808-1.968-1.592-2.2260.0-3.119-2.226-3.119-2.2260.252-0.2940.32.073
11-0.384-3.119-0.066-2.576-0.032-4.393-1.207-4.393-0.384-4.393-0.066-3.1191.967-1.5921.328-1.762
120.94-0.7131.6680.12-2.576-3.119-2.576-2.576-0.535-0.4821.3020.062-2.226-4.393-2.226-2.576
130.4730.12-1.762-0.852-1.106-0.852-4.393-0.931.3191.163-0.0320.227-0.4310.12-1.106-1.447
140.9770.2520.30.0310.5310.568-0.7130.654-0.713-1.014-1.447-0.93-0.713-0.78-1.1060.031