We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorNKX2-1
(GeneCards)
ModelNKX21_HUMAN.H11DI.0.A
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length13
Quality
A
Motif rank
0
ConsensusnbYKGAGWGbnhn
Best auROC (human)0.938
Best auROC (mouse)0.927
Peak sets in benchmark (human)14
Peak sets in benchmark (mouse)9
Aligned words501
TF familyNK-related factors {3.1.2}
TF subfamilyNK-2.1 {3.1.2.14}
HGNCHGNC:11825
EntrezGeneGeneID:7080
(SSTAR profile)
UniProt IDNKX21_HUMAN
UniProt ACP43699
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 10.53091
0.0005 12.396715
0.0001 15.781275
GTEx tissue expression atlas NKX2-1 expression
ReMap ChIP-seq dataset list NKX2-1 datasets
Motifs in JASPAR
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
014.051.058.014.012.047.03.042.08.051.026.029.011.047.050.047.0
026.09.01.019.037.027.02.0130.026.023.08.080.011.029.07.085.0
039.02.023.046.09.00.02.077.02.00.03.013.025.019.090.0180.0
040.00.045.00.02.03.016.00.04.04.0109.01.016.05.0295.00.0
0522.00.00.00.012.00.00.00.0465.00.00.00.01.00.00.00.0
061.01.0498.00.00.00.00.00.00.00.00.00.00.00.00.00.0
071.00.00.00.01.00.00.00.0113.00.030.0355.00.00.00.00.0
085.02.0108.00.00.00.00.00.03.00.027.00.031.03.0319.02.0
090.019.015.05.00.01.01.03.012.0123.0218.0101.00.01.01.00.0
103.02.04.03.033.047.04.060.049.086.048.052.012.031.020.046.0
1113.026.024.034.031.039.05.091.014.011.016.035.014.032.020.095.0
1223.019.017.013.026.021.03.058.014.010.020.021.055.047.066.087.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
01-1.9750.4850.613-0.788-0.9380.404-2.2340.293-1.3280.485-0.181-0.074-1.0220.4040.4650.404
02-1.6-1.215-3.126-0.490.167-0.144-2.5841.416-0.181-0.302-1.3280.932-1.022-0.074-1.4540.993
03-1.215-2.584-0.3020.383-1.215-4.4-2.5840.894-2.584-4.4-2.234-0.86-0.22-0.491.051.741
04-4.4-4.40.361-4.4-2.584-2.234-0.658-4.4-1.975-1.9751.241-3.126-0.658-1.772.234-4.4
05-0.346-4.4-4.4-4.4-0.938-4.4-4.4-4.42.689-4.4-4.4-4.4-3.126-4.4-4.4-4.4
06-3.126-3.1262.757-4.4-4.4-4.4-4.4-4.4-4.4-4.4-4.4-4.4-4.4-4.4-4.4-4.4
07-3.126-4.4-4.4-4.4-3.126-4.4-4.4-4.41.276-4.4-0.042.419-4.4-4.4-4.4-4.4
08-1.77-2.5841.231-4.4-4.4-4.4-4.4-4.4-2.234-4.4-0.144-4.4-0.008-2.2342.312-2.584
09-4.4-0.49-0.721-1.77-4.4-3.126-3.126-2.234-0.9381.3611.9321.165-4.4-3.126-3.126-4.4
10-2.234-2.584-1.975-2.2340.0540.404-1.9750.6460.4451.0040.4250.504-0.938-0.008-0.4390.383
11-0.86-0.181-0.260.083-0.0080.219-1.771.061-0.788-1.022-0.6580.112-0.7880.023-0.4391.104
12-0.302-0.49-0.599-0.86-0.181-0.392-2.2340.613-0.788-1.114-0.439-0.3920.560.4040.7411.016