We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorNKX2-5
(GeneCards)
ModelNKX25_HUMAN.H11DI.0.B
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length10
Quality
B
Motif rank
0
ConsensusnhdGAGWGbn
Best auROC (human)0.749
Best auROC (mouse)0.889
Peak sets in benchmark (human)2
Peak sets in benchmark (mouse)7
Aligned words518
TF familyNK-related factors {3.1.2}
TF subfamilyNK-4 {3.1.2.17}
HGNCHGNC:2488
EntrezGeneGeneID:1482
(SSTAR profile)
UniProt IDNKX25_HUMAN
UniProt ACP52952
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 11.092925000000001
0.0005 12.51905
0.0001 14.772925
GTEx tissue expression atlas NKX2-5 expression
ReMap ChIP-seq dataset list NKX2-5 datasets
Motifs in JASPAR
MA0063.1 (Nkx2-5; Mus musculus)
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
019.09.016.037.040.012.04.0116.037.025.012.063.014.012.017.071.0
0210.03.034.053.016.06.01.035.07.03.010.029.027.015.095.0150.0
036.03.051.00.018.02.05.02.038.01.0101.00.043.03.0221.00.0
04104.00.00.01.09.00.00.00.0375.02.00.01.02.00.00.00.0
052.00.0487.01.00.00.02.00.00.00.00.00.00.00.02.00.0
060.00.00.02.00.00.00.00.0165.02.016.0308.00.00.00.01.0
078.00.0148.09.00.00.00.02.02.01.013.00.028.01.0276.06.0
080.022.013.03.00.02.00.00.046.0121.0214.056.02.06.09.00.0
096.015.013.014.030.040.06.075.051.094.066.025.016.012.014.017.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
01-1.203-1.203-0.6460.1790.256-0.926-1.9641.3150.179-0.208-0.9260.707-0.776-0.926-0.5870.826
02-1.102-2.2220.0950.535-0.646-1.588-3.1150.124-1.443-2.222-1.102-0.062-0.132-0.7091.1161.571
03-1.588-2.2220.497-4.39-0.531-2.572-1.758-2.5720.205-3.1151.177-4.390.328-2.2221.957-4.39
041.206-4.39-4.39-3.115-1.203-4.39-4.39-4.392.486-2.572-4.39-3.115-2.572-4.39-4.39-4.39
05-2.572-4.392.747-3.115-4.39-4.39-2.572-4.39-4.39-4.39-4.39-4.39-4.39-4.39-2.572-4.39
06-4.39-4.39-4.39-2.572-4.39-4.39-4.39-4.391.666-2.572-0.6462.289-4.39-4.39-4.39-3.115
07-1.316-4.391.557-1.203-4.39-4.39-4.39-2.572-2.572-3.115-0.848-4.39-0.096-3.1152.179-1.588
08-4.39-0.334-0.848-2.222-4.39-2.572-4.39-4.390.3951.3571.9250.59-2.572-1.588-1.203-4.39
09-1.588-0.709-0.848-0.776-0.0280.256-1.5880.880.4971.1050.753-0.208-0.646-0.926-0.776-0.587