Model info
| Transcription factor | NKX2-5 (GeneCards) | ||||||||
| Model | NKX25_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 8 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | bbRAGWGv | ||||||||
| Best auROC (human) | 0.697 | ||||||||
| Best auROC (mouse) | 0.86 | ||||||||
| Peak sets in benchmark (human) | 2 | ||||||||
| Peak sets in benchmark (mouse) | 7 | ||||||||
| Aligned words | 499 | ||||||||
| TF family | NK-related factors {3.1.2} | ||||||||
| TF subfamily | NK-4 {3.1.2.17} | ||||||||
| HGNC | HGNC:2488 | ||||||||
| EntrezGene | GeneID:1482 (SSTAR profile) | ||||||||
| UniProt ID | NKX25_HUMAN | ||||||||
| UniProt AC | P52952 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | NKX2-5 expression | ||||||||
| ReMap ChIP-seq dataset list | NKX2-5 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 53.0 | 82.0 | 155.0 | 209.0 |
| 02 | 38.0 | 57.0 | 268.0 | 136.0 |
| 03 | 211.0 | 17.0 | 259.0 | 12.0 |
| 04 | 489.0 | 8.0 | 0.0 | 2.0 |
| 05 | 18.0 | 2.0 | 479.0 | 0.0 |
| 06 | 272.0 | 30.0 | 9.0 | 188.0 |
| 07 | 99.0 | 1.0 | 384.0 | 15.0 |
| 08 | 84.0 | 151.0 | 242.0 | 22.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.84 | -0.413 | 0.215 | 0.511 |
| 02 | -1.161 | -0.769 | 0.758 | 0.085 |
| 03 | 0.521 | -1.918 | 0.724 | -2.232 |
| 04 | 1.357 | -2.582 | -4.398 | -3.571 |
| 05 | -1.866 | -3.571 | 1.336 | -4.398 |
| 06 | 0.773 | -1.387 | -2.482 | 0.406 |
| 07 | -0.228 | -3.901 | 1.116 | -2.032 |
| 08 | -0.39 | 0.189 | 0.657 | -1.679 |