NKX31_HUMAN.H11MO.0.C motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

NKX3-1
(GeneCards)

Model

NKX31_HUMAN.H11MO.0.C

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

ChIP-Seq

Model release

HOCOMOCOv11

Model length

12

Quality

C

Motif rank

0

Consensus

nbdRAGTGbYWd

Best auROC (human)

0.792

Best auROC (mouse)

0.662

Peak sets in benchmark (human)

11

Peak sets in benchmark (mouse)

10

Aligned words

501

TF family

NK-related factors {3.1.2}

TF subfamily

NK-3 {3.1.2.16}

HGNC

EntrezGene

GeneID:4824
(SSTAR profile)

UniProt ID

UniProt AC

Q99801
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	5.58501
0.0005	6.367315
0.0001	7.864815

GTEx tissue expression atlas

NKX3-1 expression

ReMap ChIP-seq dataset list

NKX3-1 datasets

Motifs in JASPAR

MA0124.1 (NKX3-1; Homo sapiens)

MA0124.2 (Nkx3-1; Mus musculus)

PCM

	A	C	G	T
01	95.0	98.0	161.0	146.0
02	43.0	126.0	49.0	282.0
03	126.0	54.0	76.0	244.0
04	380.0	27.0	86.0	7.0
05	480.0	1.0	10.0	9.0
06	2.0	2.0	493.0	3.0
07	44.0	1.0	9.0	446.0
08	85.0	7.0	402.0	6.0
09	9.0	226.0	133.0	132.0
10	71.0	128.0	19.0	282.0
11	78.0	43.0	53.0	326.0
12	140.0	42.0	148.0	170.0

PWM

	A	C	G	T
01	-0.271	-0.24	0.25	0.154
02	-1.044	0.008	-0.918	0.807
03	0.008	-0.823	-0.49	0.663
04	1.104	-1.489	-0.368	-2.694
05	1.336	-3.903	-2.394	-2.484
06	-3.573	-3.573	1.363	-3.325
07	-1.022	-3.903	-2.484	1.263
08	-0.38	-2.694	1.16	-2.819
09	-2.484	0.587	0.061	0.054
10	-0.556	0.023	-1.818	0.807
11	-0.464	-1.044	-0.841	0.951
12	0.112	-1.067	0.167	0.304