Transcription factor | NR1H3 (GeneCards) | ||||||||
Model | NR1H3_HUMAN.H11DI.0.A | ||||||||
Model type | Dinucleotide PWM | ||||||||
LOGO | |||||||||
LOGO (reverse complement) | |||||||||
Data source | ChIP-Seq | ||||||||
Model release | HOCOMOCOv11 | ||||||||
Model length | 22 | ||||||||
Quality | A | ||||||||
Motif rank | 0 | ||||||||
Consensus | nvdKKbnWbbnnRGGdCAndbn | ||||||||
Best auROC (human) | 0.823 | ||||||||
Best auROC (mouse) | 0.937 | ||||||||
Peak sets in benchmark (human) | 13 | ||||||||
Peak sets in benchmark (mouse) | 10 | ||||||||
Aligned words | 502 | ||||||||
TF family | Thyroid hormone receptor-related factors (NR1) {2.1.2} | ||||||||
TF subfamily | LXR (NR1H) {2.1.2.7} | ||||||||
HGNC | HGNC:7966 | ||||||||
EntrezGene | GeneID:10062 (SSTAR profile) | ||||||||
UniProt ID | NR1H3_HUMAN | ||||||||
UniProt AC | Q13133 (TFClass) | ||||||||
Comment | |||||||||
Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
Standard thresholds |
| ||||||||
GTEx tissue expression atlas | NR1H3 expression | ||||||||
ReMap ChIP-seq dataset list | NR1H3 datasets | ||||||||
Motifs in JASPAR |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 61.0 | 25.0 | 57.0 | 16.0 | 66.0 | 31.0 | 27.0 | 20.0 | 29.0 | 24.0 | 37.0 | 11.0 | 18.0 | 10.0 | 56.0 | 12.0 |
02 | 72.0 | 13.0 | 77.0 | 12.0 | 53.0 | 10.0 | 14.0 | 13.0 | 83.0 | 12.0 | 62.0 | 20.0 | 12.0 | 4.0 | 42.0 | 1.0 |
03 | 20.0 | 16.0 | 162.0 | 22.0 | 13.0 | 9.0 | 7.0 | 10.0 | 32.0 | 5.0 | 117.0 | 41.0 | 5.0 | 7.0 | 29.0 | 5.0 |
04 | 8.0 | 7.0 | 39.0 | 16.0 | 5.0 | 8.0 | 4.0 | 20.0 | 11.0 | 21.0 | 204.0 | 79.0 | 10.0 | 0.0 | 43.0 | 25.0 |
05 | 7.0 | 7.0 | 13.0 | 7.0 | 4.0 | 4.0 | 0.0 | 28.0 | 22.0 | 44.0 | 41.0 | 183.0 | 12.0 | 31.0 | 26.0 | 71.0 |
06 | 9.0 | 22.0 | 9.0 | 5.0 | 21.0 | 27.0 | 6.0 | 32.0 | 24.0 | 27.0 | 16.0 | 13.0 | 38.0 | 101.0 | 47.0 | 103.0 |
07 | 62.0 | 5.0 | 13.0 | 12.0 | 124.0 | 8.0 | 1.0 | 44.0 | 44.0 | 0.0 | 13.0 | 21.0 | 107.0 | 7.0 | 17.0 | 22.0 |
08 | 36.0 | 182.0 | 45.0 | 74.0 | 3.0 | 12.0 | 2.0 | 3.0 | 7.0 | 13.0 | 10.0 | 14.0 | 7.0 | 55.0 | 22.0 | 15.0 |
09 | 9.0 | 15.0 | 25.0 | 4.0 | 39.0 | 87.0 | 11.0 | 125.0 | 12.0 | 46.0 | 11.0 | 10.0 | 5.0 | 27.0 | 21.0 | 53.0 |
10 | 16.0 | 12.0 | 14.0 | 23.0 | 69.0 | 45.0 | 4.0 | 57.0 | 17.0 | 25.0 | 13.0 | 13.0 | 44.0 | 59.0 | 54.0 | 35.0 |
11 | 52.0 | 26.0 | 47.0 | 21.0 | 57.0 | 47.0 | 8.0 | 29.0 | 24.0 | 21.0 | 21.0 | 19.0 | 26.0 | 33.0 | 44.0 | 25.0 |
12 | 104.0 | 7.0 | 44.0 | 4.0 | 105.0 | 7.0 | 7.0 | 8.0 | 90.0 | 3.0 | 24.0 | 3.0 | 45.0 | 6.0 | 32.0 | 11.0 |
13 | 10.0 | 2.0 | 319.0 | 13.0 | 4.0 | 0.0 | 17.0 | 2.0 | 8.0 | 1.0 | 97.0 | 1.0 | 0.0 | 0.0 | 25.0 | 1.0 |
14 | 1.0 | 1.0 | 19.0 | 1.0 | 1.0 | 0.0 | 1.0 | 1.0 | 10.0 | 5.0 | 397.0 | 46.0 | 1.0 | 0.0 | 12.0 | 4.0 |
15 | 0.0 | 2.0 | 7.0 | 4.0 | 1.0 | 1.0 | 1.0 | 3.0 | 56.0 | 52.0 | 62.0 | 259.0 | 5.0 | 6.0 | 7.0 | 34.0 |
16 | 4.0 | 54.0 | 3.0 | 1.0 | 0.0 | 55.0 | 1.0 | 5.0 | 2.0 | 67.0 | 1.0 | 7.0 | 4.0 | 269.0 | 4.0 | 23.0 |
17 | 7.0 | 1.0 | 2.0 | 0.0 | 426.0 | 3.0 | 10.0 | 6.0 | 6.0 | 1.0 | 2.0 | 0.0 | 33.0 | 0.0 | 3.0 | 0.0 |
18 | 97.0 | 118.0 | 174.0 | 83.0 | 0.0 | 1.0 | 3.0 | 1.0 | 2.0 | 4.0 | 6.0 | 5.0 | 0.0 | 1.0 | 5.0 | 0.0 |
19 | 54.0 | 6.0 | 26.0 | 13.0 | 60.0 | 17.0 | 9.0 | 38.0 | 76.0 | 31.0 | 57.0 | 24.0 | 19.0 | 20.0 | 27.0 | 23.0 |
20 | 28.0 | 38.0 | 113.0 | 30.0 | 16.0 | 20.0 | 7.0 | 31.0 | 23.0 | 15.0 | 58.0 | 23.0 | 14.0 | 10.0 | 56.0 | 18.0 |
21 | 20.0 | 12.0 | 38.0 | 11.0 | 32.0 | 16.0 | 11.0 | 24.0 | 68.0 | 26.0 | 74.0 | 66.0 | 23.0 | 27.0 | 27.0 | 25.0 |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 0.663 | -0.22 | 0.595 | -0.658 | 0.741 | -0.008 | -0.144 | -0.439 | -0.074 | -0.26 | 0.167 | -1.022 | -0.543 | -1.114 | 0.578 | -0.938 |
02 | 0.828 | -0.86 | 0.894 | -0.938 | 0.523 | -1.114 | -0.788 | -0.86 | 0.969 | -0.938 | 0.679 | -0.439 | -0.938 | -1.975 | 0.293 | -3.126 |
03 | -0.439 | -0.658 | 1.636 | -0.346 | -0.86 | -1.215 | -1.454 | -1.114 | 0.023 | -1.77 | 1.311 | 0.269 | -1.77 | -1.454 | -0.074 | -1.77 |
04 | -1.328 | -1.454 | 0.219 | -0.658 | -1.77 | -1.328 | -1.975 | -0.439 | -1.022 | -0.392 | 1.866 | 0.92 | -1.114 | -4.4 | 0.316 | -0.22 |
05 | -1.454 | -1.454 | -0.86 | -1.454 | -1.975 | -1.975 | -4.4 | -0.108 | -0.346 | 0.339 | 0.269 | 1.757 | -0.938 | -0.008 | -0.181 | 0.814 |
06 | -1.215 | -0.346 | -1.215 | -1.77 | -0.392 | -0.144 | -1.6 | 0.023 | -0.26 | -0.144 | -0.658 | -0.86 | 0.193 | 1.165 | 0.404 | 1.184 |
07 | 0.679 | -1.77 | -0.86 | -0.938 | 1.369 | -1.328 | -3.126 | 0.339 | 0.339 | -4.4 | -0.86 | -0.392 | 1.222 | -1.454 | -0.599 | -0.346 |
08 | 0.14 | 1.752 | 0.361 | 0.855 | -2.234 | -0.938 | -2.584 | -2.234 | -1.454 | -0.86 | -1.114 | -0.788 | -1.454 | 0.56 | -0.346 | -0.721 |
09 | -1.215 | -0.721 | -0.22 | -1.975 | 0.219 | 1.016 | -1.022 | 1.377 | -0.938 | 0.383 | -1.022 | -1.114 | -1.77 | -0.144 | -0.392 | 0.523 |
10 | -0.658 | -0.938 | -0.788 | -0.302 | 0.785 | 0.361 | -1.975 | 0.595 | -0.599 | -0.22 | -0.86 | -0.86 | 0.339 | 0.63 | 0.542 | 0.112 |
11 | 0.504 | -0.181 | 0.404 | -0.392 | 0.595 | 0.404 | -1.328 | -0.074 | -0.26 | -0.392 | -0.392 | -0.49 | -0.181 | 0.054 | 0.339 | -0.22 |
12 | 1.194 | -1.454 | 0.339 | -1.975 | 1.203 | -1.454 | -1.454 | -1.328 | 1.05 | -2.234 | -0.26 | -2.234 | 0.361 | -1.6 | 0.023 | -1.022 |
13 | -1.114 | -2.584 | 2.312 | -0.86 | -1.975 | -4.4 | -0.599 | -2.584 | -1.328 | -3.126 | 1.124 | -3.126 | -4.4 | -4.4 | -0.22 | -3.126 |
14 | -3.126 | -3.126 | -0.49 | -3.126 | -3.126 | -4.4 | -3.126 | -3.126 | -1.114 | -1.77 | 2.531 | 0.383 | -3.126 | -4.4 | -0.938 | -1.975 |
15 | -4.4 | -2.584 | -1.454 | -1.975 | -3.126 | -3.126 | -3.126 | -2.234 | 0.578 | 0.504 | 0.679 | 2.104 | -1.77 | -1.6 | -1.454 | 0.083 |
16 | -1.975 | 0.542 | -2.234 | -3.126 | -4.4 | 0.56 | -3.126 | -1.77 | -2.584 | 0.756 | -3.126 | -1.454 | -1.975 | 2.142 | -1.975 | -0.302 |
17 | -1.454 | -3.126 | -2.584 | -4.4 | 2.601 | -2.234 | -1.114 | -1.6 | -1.6 | -3.126 | -2.584 | -4.4 | 0.054 | -4.4 | -2.234 | -4.4 |
18 | 1.124 | 1.32 | 1.707 | 0.969 | -4.4 | -3.126 | -2.234 | -3.126 | -2.584 | -1.975 | -1.6 | -1.77 | -4.4 | -3.126 | -1.77 | -4.4 |
19 | 0.542 | -1.6 | -0.181 | -0.86 | 0.646 | -0.599 | -1.215 | 0.193 | 0.881 | -0.008 | 0.595 | -0.26 | -0.49 | -0.439 | -0.144 | -0.302 |
20 | -0.108 | 0.193 | 1.276 | -0.04 | -0.658 | -0.439 | -1.454 | -0.008 | -0.302 | -0.721 | 0.613 | -0.302 | -0.788 | -1.114 | 0.578 | -0.543 |
21 | -0.439 | -0.938 | 0.193 | -1.022 | 0.023 | -0.658 | -1.022 | -0.26 | 0.771 | -0.181 | 0.855 | 0.741 | -0.302 | -0.144 | -0.144 | -0.22 |