Model info
| Transcription factor | NR1H4 (GeneCards) | ||||||||
| Model | NR1H4_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 19 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | vRGKKSRvYGdCCbbbvGK | ||||||||
| Best auROC (human) | |||||||||
| Best auROC (mouse) | 0.926 | ||||||||
| Peak sets in benchmark (human) | |||||||||
| Peak sets in benchmark (mouse) | 15 | ||||||||
| Aligned words | 451 | ||||||||
| TF family | Thyroid hormone receptor-related factors (NR1) {2.1.2} | ||||||||
| TF subfamily | LXR (NR1H) {2.1.2.7} | ||||||||
| HGNC | HGNC:7967 | ||||||||
| EntrezGene | GeneID:9971 (SSTAR profile) | ||||||||
| UniProt ID | NR1H4_HUMAN | ||||||||
| UniProt AC | Q96RI1 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | NR1H4 expression | ||||||||
| ReMap ChIP-seq dataset list | NR1H4 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 122.0 | 88.0 | 198.0 | 43.0 |
| 02 | 217.0 | 7.0 | 222.0 | 5.0 |
| 03 | 33.0 | 4.0 | 386.0 | 28.0 |
| 04 | 46.0 | 16.0 | 334.0 | 55.0 |
| 05 | 11.0 | 55.0 | 150.0 | 235.0 |
| 06 | 13.0 | 329.0 | 66.0 | 43.0 |
| 07 | 341.0 | 27.0 | 80.0 | 3.0 |
| 08 | 167.0 | 107.0 | 133.0 | 44.0 |
| 09 | 29.0 | 81.0 | 47.0 | 294.0 |
| 10 | 30.0 | 15.0 | 402.0 | 4.0 |
| 11 | 218.0 | 43.0 | 145.0 | 45.0 |
| 12 | 32.0 | 382.0 | 26.0 | 11.0 |
| 13 | 36.0 | 363.0 | 5.0 | 47.0 |
| 14 | 35.0 | 161.0 | 126.0 | 129.0 |
| 15 | 77.0 | 190.0 | 106.0 | 78.0 |
| 16 | 54.0 | 99.0 | 214.0 | 84.0 |
| 17 | 144.0 | 131.0 | 138.0 | 38.0 |
| 18 | 32.0 | 3.0 | 365.0 | 51.0 |
| 19 | 33.0 | 29.0 | 348.0 | 41.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.078 | -0.244 | 0.557 | -0.943 |
| 02 | 0.648 | -2.595 | 0.671 | -2.863 |
| 03 | -1.197 | -3.029 | 1.221 | -1.353 |
| 04 | -0.877 | -1.875 | 1.077 | -0.704 |
| 05 | -2.211 | -0.704 | 0.282 | 0.727 |
| 06 | -2.063 | 1.062 | -0.526 | -0.943 |
| 07 | 1.098 | -1.388 | -0.338 | -3.228 |
| 08 | 0.388 | -0.052 | 0.163 | -0.92 |
| 09 | -1.32 | -0.325 | -0.856 | 0.95 |
| 10 | -1.288 | -1.934 | 1.262 | -3.029 |
| 11 | 0.653 | -0.943 | 0.249 | -0.899 |
| 12 | -1.226 | 1.211 | -1.423 | -2.211 |
| 13 | -1.114 | 1.16 | -2.863 | -0.856 |
| 14 | -1.141 | 0.352 | 0.11 | 0.133 |
| 15 | -0.375 | 0.516 | -0.061 | -0.363 |
| 16 | -0.722 | -0.128 | 0.634 | -0.29 |
| 17 | 0.242 | 0.148 | 0.2 | -1.062 |
| 18 | -1.226 | -3.228 | 1.165 | -0.777 |
| 19 | -1.197 | -1.32 | 1.118 | -0.988 |