Model info
| Transcription factor | NR1H4 (GeneCards) | ||||||||
| Model | NR1H4_HUMAN.H11MO.1.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 8 | ||||||||
| Quality | B | ||||||||
| Motif rank | 1 | ||||||||
| Consensus | RGGKCAbh | ||||||||
| Best auROC (human) | |||||||||
| Best auROC (mouse) | 0.849 | ||||||||
| Peak sets in benchmark (human) | |||||||||
| Peak sets in benchmark (mouse) | 15 | ||||||||
| Aligned words | 501 | ||||||||
| TF family | Thyroid hormone receptor-related factors (NR1) {2.1.2} | ||||||||
| TF subfamily | LXR (NR1H) {2.1.2.7} | ||||||||
| HGNC | HGNC:7967 | ||||||||
| EntrezGene | GeneID:9971 (SSTAR profile) | ||||||||
| UniProt ID | NR1H4_HUMAN | ||||||||
| UniProt AC | Q96RI1 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | NR1H4 expression | ||||||||
| ReMap ChIP-seq dataset list | NR1H4 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 274.0 | 18.0 | 194.0 | 14.0 |
| 02 | 1.0 | 1.0 | 494.0 | 4.0 |
| 03 | 6.0 | 11.0 | 480.0 | 3.0 |
| 04 | 19.0 | 47.0 | 74.0 | 360.0 |
| 05 | 3.0 | 486.0 | 10.0 | 1.0 |
| 06 | 465.0 | 28.0 | 5.0 | 2.0 |
| 07 | 48.0 | 98.0 | 231.0 | 123.0 |
| 08 | 76.0 | 109.0 | 71.0 | 244.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.778 | -1.868 | 0.435 | -2.096 |
| 02 | -3.903 | -3.903 | 1.365 | -3.126 |
| 03 | -2.819 | -2.311 | 1.336 | -3.325 |
| 04 | -1.818 | -0.958 | -0.516 | 1.05 |
| 05 | -3.325 | 1.349 | -2.394 | -3.903 |
| 06 | 1.305 | -1.454 | -2.961 | -3.573 |
| 07 | -0.938 | -0.24 | 0.608 | -0.016 |
| 08 | -0.49 | -0.135 | -0.556 | 0.663 |