P53_HUMAN.H11MO.1.A motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

TP53
(GeneCards)

Model

P53_HUMAN.H11MO.1.A

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

ChIP-Seq

Model release

HOCOMOCOv11

Model length

13

Quality

A

Motif rank

1

Consensus

dRRCATGYCYRKR

Best auROC (human)

0.988

Best auROC (mouse)

0.981

Peak sets in benchmark (human)

141

Peak sets in benchmark (mouse)

39

Aligned words

500

TF family

p53-related factors {6.3.1}

TF subfamily

p53 {6.3.1.0.1}

HGNC

EntrezGene

GeneID:7157
(SSTAR profile)

UniProt ID

UniProt AC

P04637
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	4.00186
0.0005	5.05441
0.0001	7.203270000000001

GTEx tissue expression atlas

TP53 expression

ReMap ChIP-seq dataset list

Motifs in JASPAR

MA0106.1 (TP53; Homo sapiens)

MA0106.2 (TP53; Homo sapiens)

MA0106.3 (TP53; Homo sapiens)

PCM

	A	C	G	T
01	111.0	43.0	280.0	66.0
02	111.0	29.0	315.0	45.0
03	268.0	3.0	204.0	25.0
04	1.0	490.0	5.0	4.0
05	423.0	0.0	3.0	74.0
06	85.0	1.0	18.0	396.0
07	0.0	4.0	496.0	0.0
08	11.0	302.0	2.0	185.0
09	11.0	444.0	11.0	34.0
10	54.0	155.0	12.0	279.0
11	104.0	25.0	334.0	37.0
12	45.0	9.0	384.0	62.0
13	140.0	10.0	337.0	13.0

PWM

	A	C	G	T
01	-0.117	-1.044	0.8	-0.628
02	-0.117	-1.421	0.917	-1.0
03	0.756	-3.325	0.485	-1.561
04	-3.903	1.357	-2.961	-3.126
05	1.21	-4.4	-3.325	-0.516
06	-0.38	-3.903	-1.868	1.145
07	-4.4	-3.126	1.369	-4.4
08	-2.311	0.875	-3.573	0.388
09	-2.311	1.259	-2.311	-1.27
10	-0.823	0.213	-2.234	0.796
11	-0.181	-1.561	0.975	-1.189
12	-1.0	-2.484	1.114	-0.689
13	0.112	-2.394	0.984	-2.163