We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorRUNX2
(GeneCards)
ModelRUNX2_HUMAN.H11DI.0.A
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length17
Quality
A
Motif rank
0
ConsensusndddbbdbTGTGGTYWn
Best auROC (human)0.971
Best auROC (mouse)0.902
Peak sets in benchmark (human)3
Peak sets in benchmark (mouse)25
Aligned words559
TF familyRunt-related factors {6.4.1}
TF subfamilyRunx2 (PEBP2alphaA, CBF-alpha1) {6.4.1.0.1}
HGNCHGNC:10472
EntrezGeneGeneID:860
(SSTAR profile)
UniProt IDRUNX2_HUMAN
UniProt ACQ13950
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 8.91491
0.0005 11.10941
0.0001 15.51956
GTEx tissue expression atlas RUNX2 expression
ReMap ChIP-seq dataset list RUNX2 datasets
Motifs in JASPAR
MA0511.1 (RUNX2; Homo sapiens)
MA0511.2 (RUNX2; Homo sapiens)
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
0111.08.026.037.023.018.06.035.020.011.019.0110.024.017.059.068.0
0213.010.033.022.022.07.08.017.010.010.042.048.015.027.0146.062.0
0314.07.024.015.014.010.08.022.024.023.0117.065.017.013.072.047.0
042.09.040.018.07.016.07.023.027.017.087.090.010.06.084.049.0
058.010.015.013.018.015.010.05.026.035.0100.057.017.030.098.035.0
0613.013.07.036.021.014.02.053.032.029.054.0108.012.013.013.072.0
077.035.015.021.010.033.06.020.08.031.01.036.07.090.065.0107.0
081.03.04.024.00.04.05.0180.02.02.01.082.01.04.016.0163.0
090.00.04.00.00.00.013.00.00.00.025.01.02.08.0412.027.0
100.00.00.02.00.00.01.07.07.015.03.0429.00.00.00.028.0
110.00.07.00.00.00.015.00.00.00.04.00.00.01.0464.01.0
120.00.00.00.00.00.01.00.01.00.0488.01.00.00.01.00.0
130.01.00.00.00.00.00.00.07.044.048.0391.00.00.00.01.0
142.01.02.02.05.07.00.033.04.010.01.033.019.039.041.0293.0
1513.00.05.012.017.03.06.031.010.01.010.023.068.08.059.0226.0
1628.016.038.026.05.03.01.03.030.07.026.017.047.040.0104.0101.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
01-1.006-1.312-0.1660.183-0.286-0.527-1.5840.128-0.423-1.006-0.4741.266-0.244-0.5830.6460.787
02-0.844-1.0980.07-0.33-0.33-1.439-1.312-0.583-1.098-1.0980.3080.441-0.705-0.1281.5480.695
03-0.772-1.439-0.244-0.705-0.772-1.098-1.312-0.33-0.244-0.2861.3270.742-0.583-0.8440.8440.42
04-2.568-1.1990.26-0.527-1.439-0.642-1.439-0.286-0.128-0.5831.0321.066-1.098-1.5840.9970.461
05-1.312-1.098-0.705-0.844-0.527-0.705-1.098-1.754-0.1660.1281.1710.611-0.583-0.0241.1510.128
06-0.844-0.844-1.4390.156-0.376-0.772-2.5680.5390.039-0.0580.5581.247-0.922-0.844-0.8440.844
07-1.4390.128-0.705-0.376-1.0980.07-1.584-0.423-1.3120.008-3.1110.156-1.4391.0660.7421.238
08-3.111-2.218-1.96-0.244-4.387-1.96-1.7541.757-2.568-2.568-3.1110.973-3.111-1.96-0.6421.658
09-4.387-4.387-1.96-4.387-4.387-4.387-0.844-4.387-4.387-4.387-0.204-3.111-2.568-1.3122.584-0.128
10-4.387-4.387-4.387-2.568-4.387-4.387-3.111-1.439-1.439-0.705-2.2182.624-4.387-4.387-4.387-0.092
11-4.387-4.387-1.439-4.387-4.387-4.387-0.705-4.387-4.387-4.387-1.96-4.387-4.387-3.1112.702-3.111
12-4.387-4.387-4.387-4.387-4.387-4.387-3.111-4.387-3.111-4.3872.753-3.111-4.387-4.387-3.111-4.387
13-4.387-3.111-4.387-4.387-4.387-4.387-4.387-4.387-1.4390.3550.4412.531-4.387-4.387-4.387-3.111
14-2.568-3.111-2.568-2.568-1.754-1.439-4.3870.07-1.96-1.098-3.1110.07-0.4740.2350.2852.243
15-0.844-4.387-1.754-0.922-0.583-2.218-1.5840.008-1.098-3.111-1.098-0.2860.787-1.3120.6461.984
16-0.092-0.6420.209-0.166-1.754-2.218-3.111-2.218-0.024-1.439-0.166-0.5830.420.261.211.181