Transcription factor | RUNX2 (GeneCards) | ||||||||
Model | RUNX2_HUMAN.H11DI.0.A | ||||||||
Model type | Dinucleotide PWM | ||||||||
LOGO | |||||||||
LOGO (reverse complement) | |||||||||
Data source | ChIP-Seq | ||||||||
Model release | HOCOMOCOv11 | ||||||||
Model length | 17 | ||||||||
Quality | A | ||||||||
Motif rank | 0 | ||||||||
Consensus | ndddbbdbTGTGGTYWn | ||||||||
Best auROC (human) | 0.971 | ||||||||
Best auROC (mouse) | 0.902 | ||||||||
Peak sets in benchmark (human) | 3 | ||||||||
Peak sets in benchmark (mouse) | 25 | ||||||||
Aligned words | 559 | ||||||||
TF family | Runt-related factors {6.4.1} | ||||||||
TF subfamily | Runx2 (PEBP2alphaA, CBF-alpha1) {6.4.1.0.1} | ||||||||
HGNC | HGNC:10472 | ||||||||
EntrezGene | GeneID:860 (SSTAR profile) | ||||||||
UniProt ID | RUNX2_HUMAN | ||||||||
UniProt AC | Q13950 (TFClass) | ||||||||
Comment | |||||||||
Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
Standard thresholds |
| ||||||||
GTEx tissue expression atlas | RUNX2 expression | ||||||||
ReMap ChIP-seq dataset list | RUNX2 datasets | ||||||||
Motifs in JASPAR |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 11.0 | 8.0 | 26.0 | 37.0 | 23.0 | 18.0 | 6.0 | 35.0 | 20.0 | 11.0 | 19.0 | 110.0 | 24.0 | 17.0 | 59.0 | 68.0 |
02 | 13.0 | 10.0 | 33.0 | 22.0 | 22.0 | 7.0 | 8.0 | 17.0 | 10.0 | 10.0 | 42.0 | 48.0 | 15.0 | 27.0 | 146.0 | 62.0 |
03 | 14.0 | 7.0 | 24.0 | 15.0 | 14.0 | 10.0 | 8.0 | 22.0 | 24.0 | 23.0 | 117.0 | 65.0 | 17.0 | 13.0 | 72.0 | 47.0 |
04 | 2.0 | 9.0 | 40.0 | 18.0 | 7.0 | 16.0 | 7.0 | 23.0 | 27.0 | 17.0 | 87.0 | 90.0 | 10.0 | 6.0 | 84.0 | 49.0 |
05 | 8.0 | 10.0 | 15.0 | 13.0 | 18.0 | 15.0 | 10.0 | 5.0 | 26.0 | 35.0 | 100.0 | 57.0 | 17.0 | 30.0 | 98.0 | 35.0 |
06 | 13.0 | 13.0 | 7.0 | 36.0 | 21.0 | 14.0 | 2.0 | 53.0 | 32.0 | 29.0 | 54.0 | 108.0 | 12.0 | 13.0 | 13.0 | 72.0 |
07 | 7.0 | 35.0 | 15.0 | 21.0 | 10.0 | 33.0 | 6.0 | 20.0 | 8.0 | 31.0 | 1.0 | 36.0 | 7.0 | 90.0 | 65.0 | 107.0 |
08 | 1.0 | 3.0 | 4.0 | 24.0 | 0.0 | 4.0 | 5.0 | 180.0 | 2.0 | 2.0 | 1.0 | 82.0 | 1.0 | 4.0 | 16.0 | 163.0 |
09 | 0.0 | 0.0 | 4.0 | 0.0 | 0.0 | 0.0 | 13.0 | 0.0 | 0.0 | 0.0 | 25.0 | 1.0 | 2.0 | 8.0 | 412.0 | 27.0 |
10 | 0.0 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 1.0 | 7.0 | 7.0 | 15.0 | 3.0 | 429.0 | 0.0 | 0.0 | 0.0 | 28.0 |
11 | 0.0 | 0.0 | 7.0 | 0.0 | 0.0 | 0.0 | 15.0 | 0.0 | 0.0 | 0.0 | 4.0 | 0.0 | 0.0 | 1.0 | 464.0 | 1.0 |
12 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 1.0 | 0.0 | 1.0 | 0.0 | 488.0 | 1.0 | 0.0 | 0.0 | 1.0 | 0.0 |
13 | 0.0 | 1.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 7.0 | 44.0 | 48.0 | 391.0 | 0.0 | 0.0 | 0.0 | 1.0 |
14 | 2.0 | 1.0 | 2.0 | 2.0 | 5.0 | 7.0 | 0.0 | 33.0 | 4.0 | 10.0 | 1.0 | 33.0 | 19.0 | 39.0 | 41.0 | 293.0 |
15 | 13.0 | 0.0 | 5.0 | 12.0 | 17.0 | 3.0 | 6.0 | 31.0 | 10.0 | 1.0 | 10.0 | 23.0 | 68.0 | 8.0 | 59.0 | 226.0 |
16 | 28.0 | 16.0 | 38.0 | 26.0 | 5.0 | 3.0 | 1.0 | 3.0 | 30.0 | 7.0 | 26.0 | 17.0 | 47.0 | 40.0 | 104.0 | 101.0 |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | -1.006 | -1.312 | -0.166 | 0.183 | -0.286 | -0.527 | -1.584 | 0.128 | -0.423 | -1.006 | -0.474 | 1.266 | -0.244 | -0.583 | 0.646 | 0.787 |
02 | -0.844 | -1.098 | 0.07 | -0.33 | -0.33 | -1.439 | -1.312 | -0.583 | -1.098 | -1.098 | 0.308 | 0.441 | -0.705 | -0.128 | 1.548 | 0.695 |
03 | -0.772 | -1.439 | -0.244 | -0.705 | -0.772 | -1.098 | -1.312 | -0.33 | -0.244 | -0.286 | 1.327 | 0.742 | -0.583 | -0.844 | 0.844 | 0.42 |
04 | -2.568 | -1.199 | 0.26 | -0.527 | -1.439 | -0.642 | -1.439 | -0.286 | -0.128 | -0.583 | 1.032 | 1.066 | -1.098 | -1.584 | 0.997 | 0.461 |
05 | -1.312 | -1.098 | -0.705 | -0.844 | -0.527 | -0.705 | -1.098 | -1.754 | -0.166 | 0.128 | 1.171 | 0.611 | -0.583 | -0.024 | 1.151 | 0.128 |
06 | -0.844 | -0.844 | -1.439 | 0.156 | -0.376 | -0.772 | -2.568 | 0.539 | 0.039 | -0.058 | 0.558 | 1.247 | -0.922 | -0.844 | -0.844 | 0.844 |
07 | -1.439 | 0.128 | -0.705 | -0.376 | -1.098 | 0.07 | -1.584 | -0.423 | -1.312 | 0.008 | -3.111 | 0.156 | -1.439 | 1.066 | 0.742 | 1.238 |
08 | -3.111 | -2.218 | -1.96 | -0.244 | -4.387 | -1.96 | -1.754 | 1.757 | -2.568 | -2.568 | -3.111 | 0.973 | -3.111 | -1.96 | -0.642 | 1.658 |
09 | -4.387 | -4.387 | -1.96 | -4.387 | -4.387 | -4.387 | -0.844 | -4.387 | -4.387 | -4.387 | -0.204 | -3.111 | -2.568 | -1.312 | 2.584 | -0.128 |
10 | -4.387 | -4.387 | -4.387 | -2.568 | -4.387 | -4.387 | -3.111 | -1.439 | -1.439 | -0.705 | -2.218 | 2.624 | -4.387 | -4.387 | -4.387 | -0.092 |
11 | -4.387 | -4.387 | -1.439 | -4.387 | -4.387 | -4.387 | -0.705 | -4.387 | -4.387 | -4.387 | -1.96 | -4.387 | -4.387 | -3.111 | 2.702 | -3.111 |
12 | -4.387 | -4.387 | -4.387 | -4.387 | -4.387 | -4.387 | -3.111 | -4.387 | -3.111 | -4.387 | 2.753 | -3.111 | -4.387 | -4.387 | -3.111 | -4.387 |
13 | -4.387 | -3.111 | -4.387 | -4.387 | -4.387 | -4.387 | -4.387 | -4.387 | -1.439 | 0.355 | 0.441 | 2.531 | -4.387 | -4.387 | -4.387 | -3.111 |
14 | -2.568 | -3.111 | -2.568 | -2.568 | -1.754 | -1.439 | -4.387 | 0.07 | -1.96 | -1.098 | -3.111 | 0.07 | -0.474 | 0.235 | 0.285 | 2.243 |
15 | -0.844 | -4.387 | -1.754 | -0.922 | -0.583 | -2.218 | -1.584 | 0.008 | -1.098 | -3.111 | -1.098 | -0.286 | 0.787 | -1.312 | 0.646 | 1.984 |
16 | -0.092 | -0.642 | 0.209 | -0.166 | -1.754 | -2.218 | -3.111 | -2.218 | -0.024 | -1.439 | -0.166 | -0.583 | 0.42 | 0.26 | 1.21 | 1.181 |