We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorRUNX2
(GeneCards)
ModelRUNX2_HUMAN.H11MO.0.A
Model typeMononucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length14
Quality
A
Motif rank
0
ConsensusdbbbTGTGGYKKnb
Best auROC (human)0.965
Best auROC (mouse)0.894
Peak sets in benchmark (human)3
Peak sets in benchmark (mouse)25
Aligned words502
TF familyRunt-related factors {6.4.1}
TF subfamilyRunx2 (PEBP2alphaA, CBF-alpha1) {6.4.1.0.1}
HGNCHGNC:10472
EntrezGeneGeneID:860
(SSTAR profile)
UniProt IDRUNX2_HUMAN
UniProt ACQ13950
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 4.95536
0.0005 5.91451
0.0001 7.855815
GTEx tissue expression atlas RUNX2 expression
ReMap ChIP-seq dataset list RUNX2 datasets
Motifs in JASPAR
MA0511.1 (RUNX2; Homo sapiens)
MA0511.2 (RUNX2; Homo sapiens)
PCM
ACGT
0186.038.0158.0218.0
0246.065.0261.0128.0
0357.065.0146.0232.0
0461.0199.088.0152.0
0534.05.08.0453.0
064.08.0462.026.0
0717.014.013.0456.0
081.00.0499.00.0
091.02.0487.010.0
109.073.056.0362.0
1116.069.080.0335.0
1288.013.096.0303.0
1357.055.0194.0194.0
1449.065.0190.0196.0
PWM
ACGT
01-0.368-1.1630.2320.551
02-0.979-0.6430.730.023
03-0.771-0.6430.1540.613
04-0.7050.46-0.3460.193
05-1.27-2.961-2.5841.279
06-3.126-2.5841.298-1.525
07-1.92-2.096-2.1631.285
08-3.903-4.41.375-4.4
09-3.903-3.5731.351-2.394
10-2.484-0.529-0.7881.055
11-1.975-0.584-0.4390.978
12-0.346-2.163-0.260.878
13-0.771-0.8050.4350.435
14-0.918-0.6430.4150.445