Model info
| Transcription factor | RUNX2 (GeneCards) | ||||||||
| Model | RUNX2_HUMAN.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 14 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | dbbbTGTGGYKKnb | ||||||||
| Best auROC (human) | 0.965 | ||||||||
| Best auROC (mouse) | 0.894 | ||||||||
| Peak sets in benchmark (human) | 3 | ||||||||
| Peak sets in benchmark (mouse) | 25 | ||||||||
| Aligned words | 502 | ||||||||
| TF family | Runt-related factors {6.4.1} | ||||||||
| TF subfamily | Runx2 (PEBP2alphaA, CBF-alpha1) {6.4.1.0.1} | ||||||||
| HGNC | HGNC:10472 | ||||||||
| EntrezGene | GeneID:860 (SSTAR profile) | ||||||||
| UniProt ID | RUNX2_HUMAN | ||||||||
| UniProt AC | Q13950 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | RUNX2 expression | ||||||||
| ReMap ChIP-seq dataset list | RUNX2 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 86.0 | 38.0 | 158.0 | 218.0 |
| 02 | 46.0 | 65.0 | 261.0 | 128.0 |
| 03 | 57.0 | 65.0 | 146.0 | 232.0 |
| 04 | 61.0 | 199.0 | 88.0 | 152.0 |
| 05 | 34.0 | 5.0 | 8.0 | 453.0 |
| 06 | 4.0 | 8.0 | 462.0 | 26.0 |
| 07 | 17.0 | 14.0 | 13.0 | 456.0 |
| 08 | 1.0 | 0.0 | 499.0 | 0.0 |
| 09 | 1.0 | 2.0 | 487.0 | 10.0 |
| 10 | 9.0 | 73.0 | 56.0 | 362.0 |
| 11 | 16.0 | 69.0 | 80.0 | 335.0 |
| 12 | 88.0 | 13.0 | 96.0 | 303.0 |
| 13 | 57.0 | 55.0 | 194.0 | 194.0 |
| 14 | 49.0 | 65.0 | 190.0 | 196.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.368 | -1.163 | 0.232 | 0.551 |
| 02 | -0.979 | -0.643 | 0.73 | 0.023 |
| 03 | -0.771 | -0.643 | 0.154 | 0.613 |
| 04 | -0.705 | 0.46 | -0.346 | 0.193 |
| 05 | -1.27 | -2.961 | -2.584 | 1.279 |
| 06 | -3.126 | -2.584 | 1.298 | -1.525 |
| 07 | -1.92 | -2.096 | -2.163 | 1.285 |
| 08 | -3.903 | -4.4 | 1.375 | -4.4 |
| 09 | -3.903 | -3.573 | 1.351 | -2.394 |
| 10 | -2.484 | -0.529 | -0.788 | 1.055 |
| 11 | -1.975 | -0.584 | -0.439 | 0.978 |
| 12 | -0.346 | -2.163 | -0.26 | 0.878 |
| 13 | -0.771 | -0.805 | 0.435 | 0.435 |
| 14 | -0.918 | -0.643 | 0.415 | 0.445 |