We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorRunx2
ModelRUNX2_MOUSE.H11DI.0.A
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length13
Quality
A
Motif rank
0
ConsensusnbYTGTGGTYdbn
Best auROC (human)0.856
Best auROC (mouse)0.937
Peak sets in benchmark (human)3
Peak sets in benchmark (mouse)25
Aligned words547
TF familyRunt-related factors {6.4.1}
TF subfamilyRunx2 (PEBP2alphaA, CBF-alpha1) {6.4.1.0.1}
MGIMGI:99829
EntrezGeneGeneID:12393
(SSTAR profile)
UniProt IDRUNX2_MOUSE
UniProt ACQ08775
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 7.51956
0.0005 9.99022
0.0001 15.482265000000002
GTEx tissue expression atlas Runx2 expression
Motifs in JASPAR
MA0511.1 (RUNX2; Homo sapiens)
MA0511.2 (RUNX2; Homo sapiens)
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
015.017.026.018.024.027.011.064.019.058.051.044.013.047.021.054.0
025.034.09.013.013.077.06.053.010.069.08.022.04.0100.018.058.0
032.00.00.030.02.03.01.0274.00.02.00.039.03.06.03.0134.0
040.00.07.00.00.00.011.00.01.00.03.00.03.03.0471.00.0
050.00.01.03.01.01.00.01.04.067.04.0417.00.00.00.00.0
060.00.05.00.00.00.067.01.00.00.05.00.00.00.0419.02.0
070.00.00.00.00.00.00.00.01.00.0495.00.00.00.03.00.0
080.00.00.01.00.00.00.00.00.039.06.0453.00.00.00.00.0
090.00.00.00.00.03.01.035.00.01.00.05.013.0113.027.0301.0
106.01.01.05.057.010.07.043.04.03.09.012.070.014.046.0211.0
1118.022.080.017.08.07.07.06.013.016.022.012.016.078.0111.066.0
1220.014.019.02.023.042.011.047.043.045.091.041.014.026.035.026.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
01-1.768-0.597-0.179-0.541-0.258-0.142-1.020.713-0.4880.6150.4870.341-0.8580.406-0.390.544
02-1.7680.085-1.213-0.858-0.8580.896-1.5980.525-1.1120.787-1.326-0.344-1.9731.157-0.5410.615
03-2.582-4.398-4.398-0.038-2.582-2.232-3.1242.162-4.398-2.582-4.3980.221-2.232-1.598-2.2321.448
04-4.398-4.398-1.452-4.398-4.398-4.398-1.02-4.398-3.124-4.398-2.232-4.398-2.232-2.2322.703-4.398
05-4.398-4.398-3.124-2.232-3.124-3.124-4.398-3.124-1.9730.758-1.9732.582-4.398-4.398-4.398-4.398
06-4.398-4.398-1.768-4.398-4.398-4.3980.758-3.124-4.398-4.398-1.768-4.398-4.398-4.3982.586-2.582
07-4.398-4.398-4.398-4.398-4.398-4.398-4.398-4.398-3.124-4.3982.753-4.398-4.398-4.398-2.232-4.398
08-4.398-4.398-4.398-3.124-4.398-4.398-4.398-4.398-4.3980.221-1.5982.664-4.398-4.398-4.398-4.398
09-4.398-4.398-4.398-4.398-4.398-2.232-3.1240.114-4.398-3.124-4.398-1.768-0.8581.278-0.1422.256
10-1.598-3.124-3.124-1.7680.597-1.112-1.4520.318-1.973-2.232-1.213-0.9360.802-0.7860.3851.901
11-0.541-0.3440.934-0.597-1.326-1.452-1.452-1.598-0.858-0.656-0.344-0.936-0.6560.9091.2610.743
12-0.437-0.786-0.488-2.582-0.30.294-1.020.4060.3180.3631.0630.271-0.786-0.1790.114-0.179