Model info
| Transcription factor | Runx2 | ||||||||
| Model | RUNX2_MOUSE.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 12 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | bbYTGTGGYYdb | ||||||||
| Best auROC (human) | 0.837 | ||||||||
| Best auROC (mouse) | 0.927 | ||||||||
| Peak sets in benchmark (human) | 3 | ||||||||
| Peak sets in benchmark (mouse) | 25 | ||||||||
| Aligned words | 501 | ||||||||
| TF family | Runt-related factors {6.4.1} | ||||||||
| TF subfamily | Runx2 (PEBP2alphaA, CBF-alpha1) {6.4.1.0.1} | ||||||||
| MGI | MGI:99829 | ||||||||
| EntrezGene | GeneID:12393 (SSTAR profile) | ||||||||
| UniProt ID | RUNX2_MOUSE | ||||||||
| UniProt AC | Q08775 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | Runx2 expression | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 53.0 | 139.0 | 184.0 | 124.0 |
| 02 | 49.0 | 154.0 | 94.0 | 203.0 |
| 03 | 17.0 | 305.0 | 41.0 | 137.0 |
| 04 | 16.0 | 10.0 | 4.0 | 470.0 |
| 05 | 2.0 | 9.0 | 481.0 | 8.0 |
| 06 | 16.0 | 51.0 | 13.0 | 420.0 |
| 07 | 0.0 | 0.0 | 499.0 | 1.0 |
| 08 | 10.0 | 2.0 | 483.0 | 5.0 |
| 09 | 4.0 | 87.0 | 31.0 | 378.0 |
| 10 | 11.0 | 118.0 | 30.0 | 341.0 |
| 11 | 138.0 | 24.0 | 72.0 | 266.0 |
| 12 | 41.0 | 140.0 | 180.0 | 139.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.841 | 0.105 | 0.383 | -0.008 |
| 02 | -0.918 | 0.206 | -0.281 | 0.48 |
| 03 | -1.92 | 0.885 | -1.09 | 0.091 |
| 04 | -1.975 | -2.394 | -3.126 | 1.315 |
| 05 | -3.573 | -2.484 | 1.338 | -2.584 |
| 06 | -1.975 | -0.879 | -2.163 | 1.203 |
| 07 | -4.4 | -4.4 | 1.375 | -3.903 |
| 08 | -2.394 | -3.573 | 1.343 | -2.961 |
| 09 | -3.126 | -0.357 | -1.358 | 1.098 |
| 10 | -2.311 | -0.057 | -1.389 | 0.996 |
| 11 | 0.098 | -1.6 | -0.543 | 0.749 |
| 12 | -1.09 | 0.112 | 0.361 | 0.105 |