We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorSIX2
(GeneCards)
ModelSIX2_HUMAN.H11DI.0.A
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length16
Quality
A
Motif rank
0
ConsensusndGdAAbhhRAbMYbn
Best auROC (human)0.975
Best auROC (mouse)0.96
Peak sets in benchmark (human)18
Peak sets in benchmark (mouse)9
Aligned words489
TF familyHD-SINE factors {3.1.6}
TF subfamilySIX1-like factors {3.1.6.1}
HGNCHGNC:10888
EntrezGeneGeneID:10736
(SSTAR profile)
UniProt IDSIX2_HUMAN
UniProt ACQ9NPC8
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 10.89641
0.0005 12.36626
0.0001 15.29871
GTEx tissue expression atlas SIX2 expression
ReMap ChIP-seq dataset list SIX2 datasets
Motifs in JASPAR
MA1119.1 (SIX2; Homo sapiens)
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
0134.01.045.037.040.05.07.090.026.00.033.055.011.04.049.044.0
021.06.0100.04.01.00.06.03.06.04.0120.04.05.03.0210.08.0
034.03.05.01.07.02.01.03.0190.025.045.0176.05.01.06.07.0
04171.016.06.013.024.05.01.01.045.08.01.03.0148.014.09.016.0
05374.02.06.06.041.00.01.01.013.02.01.01.027.03.02.01.0
0631.0223.041.0160.01.04.00.02.02.05.00.03.00.04.03.02.0
079.016.02.07.045.0114.05.072.011.021.02.010.035.049.016.067.0
0827.012.015.046.022.042.09.0127.08.01.04.012.020.031.027.078.0
0924.03.043.07.031.012.028.015.09.07.032.07.030.028.0187.018.0
1080.05.05.04.042.05.01.02.0279.04.04.03.040.04.03.00.0
1149.087.0158.0147.05.07.03.03.02.05.04.02.01.04.04.00.0
1228.023.02.04.063.028.00.012.076.068.03.022.057.081.07.07.0
1336.0131.021.036.019.0109.05.067.01.05.01.05.05.026.02.012.0
1410.018.028.05.049.0123.029.070.00.015.07.07.010.045.039.026.0
1513.020.027.09.085.047.014.055.016.023.046.018.017.026.030.035.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
010.122-3.090.3990.2050.282-1.732-1.4161.088-0.143-4.3680.0920.598-0.984-1.9380.4840.377
02-3.09-1.5621.193-1.938-3.09-4.368-1.562-2.196-1.562-1.9381.375-1.938-1.732-2.1961.933-1.289
03-1.938-2.196-1.732-3.09-1.416-2.546-3.09-2.1961.833-0.1820.3991.757-1.732-3.09-1.562-1.416
041.728-0.62-1.562-0.822-0.222-1.732-3.09-3.090.399-1.289-3.09-2.1961.584-0.75-1.177-0.62
052.509-2.546-1.562-1.5620.307-4.368-3.09-3.09-0.822-2.546-3.09-3.09-0.106-2.196-2.546-3.09
060.031.9930.3071.662-3.09-1.938-4.368-2.546-2.546-1.732-4.368-2.196-4.368-1.938-2.196-2.546
07-1.177-0.62-2.546-1.4160.3991.324-1.7320.866-0.984-0.353-2.546-1.0760.150.484-0.620.794
08-0.106-0.899-0.6830.421-0.3080.331-1.1771.431-1.289-3.09-1.938-0.899-0.4010.03-0.1060.946
09-0.222-2.1960.354-1.4160.03-0.899-0.07-0.683-1.177-1.4160.062-1.416-0.002-0.071.817-0.504
100.971-1.732-1.732-1.9380.331-1.732-3.09-2.5462.217-1.938-1.938-2.1960.282-1.938-2.196-4.368
110.4841.0541.6491.577-1.732-1.416-2.196-2.196-2.546-1.732-1.938-2.546-3.09-1.938-1.938-4.368
12-0.07-0.264-2.546-1.9380.733-0.07-4.368-0.8990.920.809-2.196-0.3080.6340.983-1.416-1.416
130.1781.462-0.3530.178-0.4511.279-1.7320.794-3.09-1.732-3.09-1.732-1.732-0.143-2.546-0.899
14-1.076-0.504-0.07-1.7320.4841.399-0.0360.838-4.368-0.683-1.416-1.416-1.0760.3990.257-0.143
15-0.822-0.401-0.106-1.1771.0310.442-0.750.598-0.62-0.2640.421-0.504-0.56-0.143-0.0020.15