Model info
| Transcription factor | SIX2 (GeneCards) | ||||||||
| Model | SIX2_HUMAN.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 13 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | KGWAAYhhRAbMh | ||||||||
| Best auROC (human) | 0.968 | ||||||||
| Best auROC (mouse) | 0.937 | ||||||||
| Peak sets in benchmark (human) | 18 | ||||||||
| Peak sets in benchmark (mouse) | 9 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | HD-SINE factors {3.1.6} | ||||||||
| TF subfamily | SIX1-like factors {3.1.6.1} | ||||||||
| HGNC | HGNC:10888 | ||||||||
| EntrezGene | GeneID:10736 (SSTAR profile) | ||||||||
| UniProt ID | SIX2_HUMAN | ||||||||
| UniProt AC | Q9NPC8 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | SIX2 expression | ||||||||
| ReMap ChIP-seq dataset list | SIX2 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 83.0 | 6.0 | 156.0 | 255.0 |
| 02 | 13.0 | 2.0 | 476.0 | 9.0 |
| 03 | 296.0 | 20.0 | 43.0 | 141.0 |
| 04 | 426.0 | 30.0 | 11.0 | 33.0 |
| 05 | 492.0 | 5.0 | 2.0 | 1.0 |
| 06 | 28.0 | 250.0 | 34.0 | 188.0 |
| 07 | 112.0 | 184.0 | 37.0 | 167.0 |
| 08 | 80.0 | 68.0 | 55.0 | 297.0 |
| 09 | 84.0 | 13.0 | 369.0 | 34.0 |
| 10 | 496.0 | 1.0 | 1.0 | 2.0 |
| 11 | 37.0 | 80.0 | 220.0 | 163.0 |
| 12 | 276.0 | 181.0 | 14.0 | 29.0 |
| 13 | 99.0 | 266.0 | 33.0 | 102.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.403 | -2.819 | 0.219 | 0.707 |
| 02 | -2.163 | -3.573 | 1.328 | -2.484 |
| 03 | 0.855 | -1.77 | -1.044 | 0.119 |
| 04 | 1.217 | -1.389 | -2.311 | -1.298 |
| 05 | 1.361 | -2.961 | -3.573 | -3.903 |
| 06 | -1.454 | 0.687 | -1.27 | 0.404 |
| 07 | -0.108 | 0.383 | -1.189 | 0.287 |
| 08 | -0.439 | -0.599 | -0.805 | 0.858 |
| 09 | -0.392 | -2.163 | 1.074 | -1.27 |
| 10 | 1.369 | -3.903 | -3.903 | -3.573 |
| 11 | -1.189 | -0.439 | 0.56 | 0.263 |
| 12 | 0.785 | 0.366 | -2.096 | -1.421 |
| 13 | -0.23 | 0.749 | -1.298 | -0.201 |