SMAD2_MOUSE.H11DI.0.A motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

Model

SMAD2_MOUSE.H11DI.0.A

Model type

Dinucleotide PWM

LOGO

LOGO (reverse complement)

Data source

ChIP-Seq

Model release

HOCOMOCOv11

Model length

14

Quality

A

Motif rank

0

Consensus

nbTGTYTGbbhhbn

Best auROC (human)

0.849

Best auROC (mouse)

0.901

Peak sets in benchmark (human)

17

Peak sets in benchmark (mouse)

26

Aligned words

501

TF family

SMAD factors {7.1.1}

TF subfamily

Regulatory Smads (R-Smad) {7.1.1.1}

MGI

EntrezGene

GeneID:17126
(SSTAR profile)

UniProt ID

UniProt AC

Q62432
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	10.791360000000001
0.0005	12.62081
0.0001	15.935760000000002

GTEx tissue expression atlas

Smad2 expression

Motifs in JASPAR

MA0513.1 (SMAD2::SMAD3::SMAD4; Homo sapiens)

PCM

	AA	AC	AG	AT	CA	CC	CG	CT	GA	GC	GG	GT	TA	TC	TG	TT
01	12.0	44.0	40.0	26.0	11.0	62.0	16.0	12.0	8.0	65.0	23.0	7.0	14.0	89.0	50.0	20.0
02	0.0	1.0	0.0	44.0	2.0	4.0	5.0	249.0	1.0	3.0	2.0	123.0	1.0	0.0	1.0	63.0
03	0.0	0.0	4.0	0.0	0.0	0.0	8.0	0.0	0.0	1.0	7.0	0.0	1.0	2.0	474.0	2.0
04	0.0	0.0	0.0	1.0	0.0	0.0	0.0	3.0	12.0	44.0	24.0	413.0	0.0	0.0	0.0	2.0
05	0.0	7.0	2.0	3.0	4.0	40.0	0.0	0.0	0.0	17.0	3.0	4.0	5.0	224.0	39.0	151.0
06	0.0	0.0	1.0	8.0	4.0	1.0	3.0	280.0	0.0	0.0	1.0	43.0	1.0	0.0	4.0	153.0
07	0.0	0.0	5.0	0.0	0.0	0.0	1.0	0.0	0.0	0.0	9.0	0.0	33.0	31.0	417.0	3.0
08	0.0	7.0	6.0	20.0	3.0	17.0	4.0	7.0	26.0	132.0	117.0	157.0	0.0	1.0	0.0	2.0
09	4.0	7.0	6.0	12.0	10.0	81.0	5.0	61.0	16.0	49.0	41.0	21.0	14.0	65.0	37.0	70.0
10	13.0	13.0	4.0	14.0	46.0	53.0	3.0	100.0	18.0	21.0	7.0	43.0	9.0	34.0	11.0	110.0
11	20.0	19.0	28.0	19.0	53.0	21.0	3.0	44.0	7.0	9.0	1.0	8.0	40.0	39.0	45.0	143.0
12	13.0	28.0	58.0	21.0	21.0	28.0	5.0	34.0	7.0	37.0	15.0	18.0	12.0	68.0	49.0	85.0
13	7.0	4.0	13.0	29.0	37.0	53.0	11.0	60.0	35.0	32.0	24.0	36.0	39.0	38.0	48.0	33.0

PWM

	AA	AC	AG	AT	CA	CC	CG	CT	GA	GC	GG	GT	TA	TC	TG	TT
01	-0.936	0.341	0.246	-0.179	-1.02	0.681	-0.656	-0.936	-1.326	0.728	-0.3	-1.452	-0.786	1.041	0.467	-0.437
02	-4.398	-3.124	-4.398	0.341	-2.582	-1.973	-1.768	2.067	-3.124	-2.232	-2.582	1.363	-3.124	-4.398	-3.124	0.697
03	-4.398	-4.398	-1.973	-4.398	-4.398	-4.398	-1.326	-4.398	-4.398	-3.124	-1.452	-4.398	-3.124	-2.582	2.71	-2.582
04	-4.398	-4.398	-4.398	-3.124	-4.398	-4.398	-4.398	-2.232	-0.936	0.341	-0.258	2.572	-4.398	-4.398	-4.398	-2.582
05	-4.398	-1.452	-2.582	-2.232	-1.973	0.246	-4.398	-4.398	-4.398	-0.597	-2.232	-1.973	-1.768	1.961	0.221	1.567
06	-4.398	-4.398	-3.124	-1.326	-1.973	-3.124	-2.232	2.184	-4.398	-4.398	-3.124	0.318	-3.124	-4.398	-1.973	1.581
07	-4.398	-4.398	-1.768	-4.398	-4.398	-4.398	-3.124	-4.398	-4.398	-4.398	-1.213	-4.398	0.056	-0.006	2.582	-2.232
08	-4.398	-1.452	-1.598	-0.437	-2.232	-0.597	-1.973	-1.452	-0.179	1.433	1.313	1.606	-4.398	-3.124	-4.398	-2.582
09	-1.973	-1.452	-1.598	-0.936	-1.112	0.947	-1.768	0.665	-0.656	0.447	0.271	-0.39	-0.786	0.728	0.169	0.802
10	-0.858	-0.858	-1.973	-0.786	0.385	0.525	-2.232	1.157	-0.541	-0.39	-1.452	0.318	-1.213	0.085	-1.02	1.252
11	-0.437	-0.488	-0.106	-0.488	0.525	-0.39	-2.232	0.341	-1.452	-1.213	-3.124	-1.326	0.246	0.221	0.363	1.513
12	-0.858	-0.106	0.615	-0.39	-0.39	-0.106	-1.768	0.085	-1.452	0.169	-0.719	-0.541	-0.936	0.773	0.447	0.995
13	-1.452	-1.973	-0.858	-0.072	0.169	0.525	-1.02	0.648	0.114	0.025	-0.258	0.142	0.221	0.195	0.427	0.056