We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorSMAD3
(GeneCards)
ModelSMAD3_HUMAN.H11DI.0.C
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length14
Quality
C
Motif rank
0
ConsensusnhvbYTvbCWSMhn
Best auROC (human)0.799
Best auROC (mouse)0.682
Peak sets in benchmark (human)34
Peak sets in benchmark (mouse)30
Aligned words506
TF familySMAD factors {7.1.1}
TF subfamilyRegulatory Smads (R-Smad) {7.1.1.1}
HGNCHGNC:6769
EntrezGeneGeneID:4088
(SSTAR profile)
UniProt IDSMAD3_HUMAN
UniProt ACP84022
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 10.22441
0.0005 11.52941
0.0001 14.17956
GTEx tissue expression atlas SMAD3 expression
ReMap ChIP-seq dataset list SMAD3 datasets
Motifs in JASPAR
MA0513.1 (SMAD2::SMAD3::SMAD4; Homo sapiens)
MA0795.1 (SMAD3; Homo sapiens)
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
0125.021.09.039.038.028.010.074.02.029.029.053.014.029.026.073.0
027.011.057.04.028.042.030.07.012.026.021.015.048.045.0138.08.0
037.016.010.062.016.042.010.056.015.044.048.0139.04.03.012.015.0
045.020.02.015.011.062.01.031.06.067.02.05.05.0218.09.040.0
056.01.00.020.024.04.05.0334.03.01.02.08.010.04.04.073.0
065.08.022.08.02.03.03.02.02.03.04.02.069.0106.0236.024.0
074.014.025.035.022.025.014.059.037.056.082.090.03.013.06.014.0
080.060.05.01.03.0100.00.05.08.0110.07.02.06.0173.014.05.0
098.07.01.01.0270.055.014.0104.015.07.01.03.04.08.00.01.0
107.0217.061.012.01.069.02.05.00.013.02.01.01.078.025.05.0
110.07.01.01.066.0271.06.034.08.068.06.08.02.015.06.00.0
1220.012.019.025.0100.047.08.0206.08.01.01.09.04.09.04.026.0
1326.042.038.026.019.019.07.024.06.013.08.05.031.069.0124.042.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
01-0.218-0.39-1.2130.2210.195-0.106-1.1120.857-2.582-0.072-0.0720.525-0.786-0.072-0.1790.843
02-1.452-1.020.597-1.973-0.1060.294-0.038-1.452-0.936-0.179-0.39-0.7190.4270.3631.478-1.326
03-1.452-0.656-1.1120.681-0.6560.294-1.1120.58-0.7190.3410.4271.485-1.973-2.232-0.936-0.719
04-1.768-0.437-2.582-0.719-1.020.681-3.124-0.006-1.5980.758-2.582-1.768-1.7681.934-1.2130.246
05-1.598-3.124-4.398-0.437-0.258-1.973-1.7682.36-2.232-3.124-2.582-1.326-1.112-1.973-1.9730.843
06-1.768-1.326-0.344-1.326-2.582-2.232-2.232-2.582-2.582-2.232-1.973-2.5820.7871.2152.013-0.258
07-1.973-0.786-0.2180.114-0.344-0.218-0.7860.6320.1690.580.9591.052-2.232-0.858-1.598-0.786
08-4.3980.648-1.768-3.124-2.2321.157-4.398-1.768-1.3261.252-1.452-2.582-1.5981.703-0.786-1.768
09-1.326-1.452-3.124-3.1242.1470.562-0.7861.196-0.719-1.452-3.124-2.232-1.973-1.326-4.398-3.124
10-1.4521.9290.665-0.936-3.1240.787-2.582-1.768-4.398-0.858-2.582-3.124-3.1240.909-0.218-1.768
11-4.398-1.452-3.124-3.1240.7432.151-1.5980.085-1.3260.773-1.598-1.326-2.582-0.719-1.598-4.398
12-0.437-0.936-0.488-0.2181.1570.406-1.3261.877-1.326-3.124-3.124-1.213-1.973-1.213-1.973-0.179
13-0.1790.2940.195-0.179-0.488-0.488-1.452-0.258-1.598-0.858-1.326-1.768-0.0060.7871.3710.294