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Model info
Transcription factorSMAD3
(GeneCards)
ModelSMAD3_HUMAN.H11DI.0.C
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length14
Quality
C
Motif rank
0
ConsensusnhvbYTvbCWSMhn
Best auROC (human)0.799
Best auROC (mouse)0.682
Peak sets in benchmark (human)34
Peak sets in benchmark (mouse)30
Aligned words506
TF familySMAD factors {7.1.1}
TF subfamilyRegulatory Smads (R-Smad) {7.1.1.1}
HGNCHGNC:6769
EntrezGeneGeneID:4088
(SSTAR profile)
UniProt IDSMAD3_HUMAN
UniProt ACP84022
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 10.22441
0.0005 11.52941
0.0001 14.17956
GTEx tissue expression atlas SMAD3 expression
ReMap ChIP-seq dataset list SMAD3 datasets
Motifs in JASPAR
MA0513.1 (SMAD2::SMAD3::SMAD4; Homo sapiens)
MA0795.1 (SMAD3; Homo sapiens)
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
0125.021.09.039.038.028.010.074.02.029.029.053.014.029.026.073.0
027.011.057.04.028.042.030.07.012.026.021.015.048.045.0138.08.0
037.016.010.062.016.042.010.056.015.044.048.0139.04.03.012.015.0
045.020.02.015.011.062.01.031.06.067.02.05.05.0218.09.040.0
056.01.00.020.024.04.05.0334.03.01.02.08.010.04.04.073.0
065.08.022.08.02.03.03.02.02.03.04.02.069.0106.0236.024.0
074.014.025.035.022.025.014.059.037.056.082.090.03.013.06.014.0
080.060.05.01.03.0100.00.05.08.0110.07.02.06.0173.014.05.0
098.07.01.01.0270.055.014.0104.015.07.01.03.04.08.00.01.0
107.0217.061.012.01.069.02.05.00.013.02.01.01.078.025.05.0
110.07.01.01.066.0271.06.034.08.068.06.08.02.015.06.00.0
1220.012.019.025.0100.047.08.0206.08.01.01.09.04.09.04.026.0
1326.042.038.026.019.019.07.024.06.013.08.05.031.069.0124.042.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
01-0.218-0.39-1.2130.2210.195-0.106-1.1120.857-2.582-0.072-0.0720.525-0.786-0.072-0.1790.843
02-1.452-1.020.597-1.973-0.1060.294-0.038-1.452-0.936-0.179-0.39-0.7190.4270.3631.478-1.326
03-1.452-0.656-1.1120.681-0.6560.294-1.1120.58-0.7190.3410.4271.485-1.973-2.232-0.936-0.719
04-1.768-0.437-2.582-0.719-1.020.681-3.124-0.006-1.5980.758-2.582-1.768-1.7681.934-1.2130.246
05-1.598-3.124-4.398-0.437-0.258-1.973-1.7682.36-2.232-3.124-2.582-1.326-1.112-1.973-1.9730.843
06-1.768-1.326-0.344-1.326-2.582-2.232-2.232-2.582-2.582-2.232-1.973-2.5820.7871.2152.013-0.258
07-1.973-0.786-0.2180.114-0.344-0.218-0.7860.6320.1690.580.9591.052-2.232-0.858-1.598-0.786
08-4.3980.648-1.768-3.124-2.2321.157-4.398-1.768-1.3261.252-1.452-2.582-1.5981.703-0.786-1.768
09-1.326-1.452-3.124-3.1242.1470.562-0.7861.196-0.719-1.452-3.124-2.232-1.973-1.326-4.398-3.124
10-1.4521.9290.665-0.936-3.1240.787-2.582-1.768-4.398-0.858-2.582-3.124-3.1240.909-0.218-1.768
11-4.398-1.452-3.124-3.1240.7432.151-1.5980.085-1.3260.773-1.598-1.326-2.582-0.719-1.598-4.398
12-0.437-0.936-0.488-0.2181.1570.406-1.3261.877-1.326-3.124-3.124-1.213-1.973-1.213-1.973-0.179
13-0.1790.2940.195-0.179-0.488-0.488-1.452-0.258-1.598-0.858-1.326-1.768-0.0060.7871.3710.294