We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorSMAD3
(GeneCards)
ModelSMAD3_HUMAN.H11MO.0.B
Model typeMononucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length12
Quality
B
Motif rank
0
ConsensusvbYTShCWSCWb
Best auROC (human)0.806
Best auROC (mouse)0.707
Peak sets in benchmark (human)34
Peak sets in benchmark (mouse)30
Aligned words500
TF familySMAD factors {7.1.1}
TF subfamilyRegulatory Smads (R-Smad) {7.1.1.1}
HGNCHGNC:6769
EntrezGeneGeneID:4088
(SSTAR profile)
UniProt IDSMAD3_HUMAN
UniProt ACP84022
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 5.339309999999999
0.0005 5.96137
0.0001 7.16828
GTEx tissue expression atlas SMAD3 expression
ReMap ChIP-seq dataset list SMAD3 datasets
Motifs in JASPAR
MA0513.1 (SMAD2::SMAD3::SMAD4; Homo sapiens)
MA0795.1 (SMAD3; Homo sapiens)
PCM
ACGT
0182.0182.0157.079.0
0255.0136.084.0225.0
0332.0348.030.090.0
04108.02.07.0383.0
0535.0147.0277.041.0
06106.0156.053.0185.0
0719.0435.04.042.0
08233.059.011.0197.0
094.0283.0166.047.0
1016.0456.07.021.0
11176.028.02.0294.0
1236.0136.0247.081.0
PWM
ACGT
01-0.4150.3720.225-0.452
02-0.8050.083-0.3920.582
03-1.3281.016-1.389-0.324
04-0.144-3.573-2.6941.111
05-1.2420.160.789-1.09
06-0.1630.219-0.8410.388
07-1.8181.238-3.126-1.067
080.617-0.737-2.3110.45
09-3.1260.810.281-0.958
10-1.9751.285-2.694-1.725
110.339-1.454-3.5730.848
12-1.2150.0830.675-0.427