Model info
| Transcription factor | SMAD3 (GeneCards) | ||||||||
| Model | SMAD3_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 12 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | vbYTShCWSCWb | ||||||||
| Best auROC (human) | 0.806 | ||||||||
| Best auROC (mouse) | 0.707 | ||||||||
| Peak sets in benchmark (human) | 34 | ||||||||
| Peak sets in benchmark (mouse) | 30 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | SMAD factors {7.1.1} | ||||||||
| TF subfamily | Regulatory Smads (R-Smad) {7.1.1.1} | ||||||||
| HGNC | HGNC:6769 | ||||||||
| EntrezGene | GeneID:4088 (SSTAR profile) | ||||||||
| UniProt ID | SMAD3_HUMAN | ||||||||
| UniProt AC | P84022 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | SMAD3 expression | ||||||||
| ReMap ChIP-seq dataset list | SMAD3 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 82.0 | 182.0 | 157.0 | 79.0 |
| 02 | 55.0 | 136.0 | 84.0 | 225.0 |
| 03 | 32.0 | 348.0 | 30.0 | 90.0 |
| 04 | 108.0 | 2.0 | 7.0 | 383.0 |
| 05 | 35.0 | 147.0 | 277.0 | 41.0 |
| 06 | 106.0 | 156.0 | 53.0 | 185.0 |
| 07 | 19.0 | 435.0 | 4.0 | 42.0 |
| 08 | 233.0 | 59.0 | 11.0 | 197.0 |
| 09 | 4.0 | 283.0 | 166.0 | 47.0 |
| 10 | 16.0 | 456.0 | 7.0 | 21.0 |
| 11 | 176.0 | 28.0 | 2.0 | 294.0 |
| 12 | 36.0 | 136.0 | 247.0 | 81.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.415 | 0.372 | 0.225 | -0.452 |
| 02 | -0.805 | 0.083 | -0.392 | 0.582 |
| 03 | -1.328 | 1.016 | -1.389 | -0.324 |
| 04 | -0.144 | -3.573 | -2.694 | 1.111 |
| 05 | -1.242 | 0.16 | 0.789 | -1.09 |
| 06 | -0.163 | 0.219 | -0.841 | 0.388 |
| 07 | -1.818 | 1.238 | -3.126 | -1.067 |
| 08 | 0.617 | -0.737 | -2.311 | 0.45 |
| 09 | -3.126 | 0.81 | 0.281 | -0.958 |
| 10 | -1.975 | 1.285 | -2.694 | -1.725 |
| 11 | 0.339 | -1.454 | -3.573 | 0.848 |
| 12 | -1.215 | 0.083 | 0.675 | -0.427 |