Model info
| Transcription factor | SMAD4 (GeneCards) | ||||||||
| Model | SMAD4_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 13 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | vWGKCTSdCWSYh | ||||||||
| Best auROC (human) | 0.869 | ||||||||
| Best auROC (mouse) | 0.671 | ||||||||
| Peak sets in benchmark (human) | 24 | ||||||||
| Peak sets in benchmark (mouse) | 3 | ||||||||
| Aligned words | 497 | ||||||||
| TF family | SMAD factors {7.1.1} | ||||||||
| TF subfamily | Co-activating Smads (Co-Smad) {7.1.1.2} | ||||||||
| HGNC | HGNC:6770 | ||||||||
| EntrezGene | GeneID:4089 (SSTAR profile) | ||||||||
| UniProt ID | SMAD4_HUMAN | ||||||||
| UniProt AC | Q13485 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | SMAD4 expression | ||||||||
| ReMap ChIP-seq dataset list | SMAD4 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 109.0 | 223.0 | 101.0 | 64.0 |
| 02 | 153.0 | 50.0 | 26.0 | 268.0 |
| 03 | 9.0 | 5.0 | 470.0 | 13.0 |
| 04 | 23.0 | 23.0 | 88.0 | 363.0 |
| 05 | 1.0 | 488.0 | 4.0 | 4.0 |
| 06 | 1.0 | 3.0 | 1.0 | 492.0 |
| 07 | 72.0 | 105.0 | 297.0 | 23.0 |
| 08 | 96.0 | 73.0 | 184.0 | 144.0 |
| 09 | 14.0 | 467.0 | 8.0 | 8.0 |
| 10 | 354.0 | 26.0 | 46.0 | 71.0 |
| 11 | 26.0 | 346.0 | 94.0 | 31.0 |
| 12 | 67.0 | 285.0 | 32.0 | 113.0 |
| 13 | 68.0 | 104.0 | 47.0 | 278.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.129 | 0.579 | -0.204 | -0.652 |
| 02 | 0.206 | -0.892 | -1.519 | 0.762 |
| 03 | -2.478 | -2.955 | 1.321 | -2.157 |
| 04 | -1.634 | -1.634 | -0.34 | 1.064 |
| 05 | -3.898 | 1.359 | -3.121 | -3.121 |
| 06 | -3.898 | -3.319 | -3.898 | 1.367 |
| 07 | -0.537 | -0.166 | 0.864 | -1.634 |
| 08 | -0.254 | -0.523 | 0.389 | 0.146 |
| 09 | -2.091 | 1.315 | -2.578 | -2.578 |
| 10 | 1.039 | -1.519 | -0.973 | -0.55 |
| 11 | -1.519 | 1.016 | -0.275 | -1.352 |
| 12 | -0.607 | 0.823 | -1.322 | -0.094 |
| 13 | -0.593 | -0.176 | -0.952 | 0.798 |