Transcription factor | SOX2 (GeneCards) | ||||||||
Model | SOX2_HUMAN.H11DI.0.A | ||||||||
Model type | Dinucleotide PWM | ||||||||
LOGO | |||||||||
LOGO (reverse complement) | |||||||||
Data source | ChIP-Seq | ||||||||
Model release | HOCOMOCOv11 | ||||||||
Model length | 18 | ||||||||
Quality | A | ||||||||
Motif rank | 0 | ||||||||
Consensus | nbYYWTTSTbhYbbhddh | ||||||||
Best auROC (human) | 0.975 | ||||||||
Best auROC (mouse) | 0.974 | ||||||||
Peak sets in benchmark (human) | 67 | ||||||||
Peak sets in benchmark (mouse) | 109 | ||||||||
Aligned words | 388 | ||||||||
TF family | SOX-related factors {4.1.1} | ||||||||
TF subfamily | Group B {4.1.1.2} | ||||||||
HGNC | HGNC:11195 | ||||||||
EntrezGene | GeneID:6657 (SSTAR profile) | ||||||||
UniProt ID | SOX2_HUMAN | ||||||||
UniProt AC | P48431 (TFClass) | ||||||||
Comment | |||||||||
Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
Standard thresholds |
| ||||||||
GTEx tissue expression atlas | SOX2 expression | ||||||||
ReMap ChIP-seq dataset list | SOX2 datasets | ||||||||
Motifs in JASPAR |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 17.0 | 12.0 | 32.0 | 22.0 | 11.0 | 32.0 | 8.0 | 36.0 | 4.0 | 36.0 | 34.0 | 19.0 | 4.0 | 35.0 | 40.0 | 46.0 |
02 | 1.0 | 20.0 | 13.0 | 2.0 | 4.0 | 74.0 | 4.0 | 33.0 | 2.0 | 78.0 | 18.0 | 16.0 | 5.0 | 67.0 | 22.0 | 29.0 |
03 | 1.0 | 9.0 | 1.0 | 1.0 | 15.0 | 130.0 | 1.0 | 93.0 | 2.0 | 39.0 | 5.0 | 11.0 | 4.0 | 57.0 | 5.0 | 14.0 |
04 | 15.0 | 1.0 | 1.0 | 5.0 | 119.0 | 5.0 | 1.0 | 110.0 | 9.0 | 0.0 | 0.0 | 3.0 | 49.0 | 4.0 | 3.0 | 63.0 |
05 | 1.0 | 4.0 | 6.0 | 181.0 | 0.0 | 0.0 | 0.0 | 10.0 | 0.0 | 1.0 | 0.0 | 4.0 | 0.0 | 3.0 | 1.0 | 177.0 |
06 | 0.0 | 0.0 | 0.0 | 1.0 | 0.0 | 1.0 | 0.0 | 7.0 | 1.0 | 0.0 | 0.0 | 6.0 | 13.0 | 0.0 | 4.0 | 355.0 |
07 | 1.0 | 3.0 | 9.0 | 1.0 | 0.0 | 1.0 | 0.0 | 0.0 | 1.0 | 2.0 | 0.0 | 1.0 | 22.0 | 66.0 | 276.0 | 5.0 |
08 | 2.0 | 2.0 | 0.0 | 20.0 | 37.0 | 1.0 | 0.0 | 34.0 | 26.0 | 3.0 | 3.0 | 253.0 | 2.0 | 1.0 | 0.0 | 4.0 |
09 | 17.0 | 9.0 | 14.0 | 27.0 | 2.0 | 2.0 | 0.0 | 3.0 | 1.0 | 0.0 | 2.0 | 0.0 | 24.0 | 75.0 | 42.0 | 170.0 |
10 | 36.0 | 1.0 | 3.0 | 4.0 | 39.0 | 29.0 | 0.0 | 18.0 | 28.0 | 10.0 | 13.0 | 7.0 | 95.0 | 63.0 | 24.0 | 18.0 |
11 | 8.0 | 12.0 | 18.0 | 160.0 | 9.0 | 35.0 | 2.0 | 57.0 | 3.0 | 13.0 | 6.0 | 18.0 | 4.0 | 5.0 | 14.0 | 24.0 |
12 | 7.0 | 2.0 | 10.0 | 5.0 | 13.0 | 22.0 | 2.0 | 28.0 | 5.0 | 9.0 | 10.0 | 16.0 | 6.0 | 24.0 | 187.0 | 42.0 |
13 | 5.0 | 4.0 | 13.0 | 9.0 | 12.0 | 26.0 | 5.0 | 14.0 | 13.0 | 149.0 | 24.0 | 23.0 | 9.0 | 40.0 | 17.0 | 25.0 |
14 | 16.0 | 6.0 | 12.0 | 5.0 | 146.0 | 22.0 | 4.0 | 47.0 | 25.0 | 20.0 | 7.0 | 7.0 | 21.0 | 9.0 | 14.0 | 27.0 |
15 | 103.0 | 11.0 | 59.0 | 35.0 | 25.0 | 12.0 | 2.0 | 18.0 | 10.0 | 3.0 | 10.0 | 14.0 | 30.0 | 12.0 | 21.0 | 23.0 |
16 | 127.0 | 12.0 | 12.0 | 17.0 | 14.0 | 11.0 | 1.0 | 12.0 | 52.0 | 11.0 | 24.0 | 5.0 | 26.0 | 13.0 | 30.0 | 21.0 |
17 | 45.0 | 22.0 | 28.0 | 124.0 | 20.0 | 9.0 | 1.0 | 17.0 | 17.0 | 18.0 | 16.0 | 16.0 | 3.0 | 16.0 | 8.0 | 28.0 |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | -0.349 | -0.688 | 0.274 | -0.096 | -0.772 | 0.274 | -1.079 | 0.39 | -1.728 | 0.39 | 0.334 | -0.24 | -1.728 | 0.362 | 0.494 | 0.633 |
02 | -2.887 | -0.189 | -0.61 | -2.34 | -1.728 | 1.105 | -1.728 | 0.304 | -2.34 | 1.158 | -0.293 | -0.408 | -1.522 | 1.007 | -0.096 | 0.176 |
03 | -2.887 | -0.966 | -2.887 | -2.887 | -0.471 | 1.667 | -2.887 | 1.333 | -2.34 | 0.469 | -1.522 | -0.772 | -1.728 | 0.846 | -1.522 | -0.538 |
04 | -0.471 | -2.887 | -2.887 | -1.522 | 1.579 | -1.522 | -2.887 | 1.5 | -0.966 | -4.191 | -4.191 | -1.988 | 0.696 | -1.728 | -1.988 | 0.945 |
05 | -2.887 | -1.728 | -1.352 | 1.997 | -4.191 | -4.191 | -4.191 | -0.864 | -4.191 | -2.887 | -4.191 | -1.728 | -4.191 | -1.988 | -2.887 | 1.975 |
06 | -4.191 | -4.191 | -4.191 | -2.887 | -4.191 | -2.887 | -4.191 | -1.206 | -2.887 | -4.191 | -4.191 | -1.352 | -0.61 | -4.191 | -1.728 | 2.67 |
07 | -2.887 | -1.988 | -0.966 | -2.887 | -4.191 | -2.887 | -4.191 | -4.191 | -2.887 | -2.34 | -4.191 | -2.887 | -0.096 | 0.992 | 2.418 | -1.522 |
08 | -2.34 | -2.34 | -4.191 | -0.189 | 0.417 | -2.887 | -4.191 | 0.334 | 0.069 | -1.988 | -1.988 | 2.331 | -2.34 | -2.887 | -4.191 | -1.728 |
09 | -0.349 | -0.966 | -0.538 | 0.106 | -2.34 | -2.34 | -4.191 | -1.988 | -2.887 | -4.191 | -2.34 | -4.191 | -0.01 | 1.119 | 0.543 | 1.934 |
10 | 0.39 | -2.887 | -1.988 | -1.728 | 0.469 | 0.176 | -4.191 | -0.293 | 0.142 | -0.864 | -0.61 | -1.206 | 1.354 | 0.945 | -0.01 | -0.293 |
11 | -1.079 | -0.688 | -0.293 | 1.874 | -0.966 | 0.362 | -2.34 | 0.846 | -1.988 | -0.61 | -1.352 | -0.293 | -1.728 | -1.522 | -0.538 | -0.01 |
12 | -1.206 | -2.34 | -0.864 | -1.522 | -0.61 | -0.096 | -2.34 | 0.142 | -1.522 | -0.966 | -0.864 | -0.408 | -1.352 | -0.01 | 2.029 | 0.543 |
13 | -1.522 | -1.728 | -0.61 | -0.966 | -0.688 | 0.069 | -1.522 | -0.538 | -0.61 | 1.803 | -0.01 | -0.052 | -0.966 | 0.494 | -0.349 | 0.03 |
14 | -0.408 | -1.352 | -0.688 | -1.522 | 1.782 | -0.096 | -1.728 | 0.654 | 0.03 | -0.189 | -1.206 | -1.206 | -0.142 | -0.966 | -0.538 | 0.106 |
15 | 1.435 | -0.772 | 0.88 | 0.362 | 0.03 | -0.688 | -2.34 | -0.293 | -0.864 | -1.988 | -0.864 | -0.538 | 0.21 | -0.688 | -0.142 | -0.052 |
16 | 1.643 | -0.688 | -0.688 | -0.349 | -0.538 | -0.772 | -2.887 | -0.688 | 0.755 | -0.772 | -0.01 | -1.522 | 0.069 | -0.61 | 0.21 | -0.142 |
17 | 0.611 | -0.096 | 0.142 | 1.62 | -0.189 | -0.966 | -2.887 | -0.349 | -0.349 | -0.293 | -0.408 | -0.408 | -1.988 | -0.408 | -1.079 | 0.142 |