Model info
| Transcription factor | SOX2 (GeneCards) | ||||||||
| Model | SOX2_HUMAN.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 13 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | bbYCTTTGTbhbb | ||||||||
| Best auROC (human) | 0.944 | ||||||||
| Best auROC (mouse) | 0.922 | ||||||||
| Peak sets in benchmark (human) | 67 | ||||||||
| Peak sets in benchmark (mouse) | 109 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | SOX-related factors {4.1.1} | ||||||||
| TF subfamily | Group B {4.1.1.2} | ||||||||
| HGNC | HGNC:11195 | ||||||||
| EntrezGene | GeneID:6657 (SSTAR profile) | ||||||||
| UniProt ID | SOX2_HUMAN | ||||||||
| UniProt AC | P48431 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | SOX2 expression | ||||||||
| ReMap ChIP-seq dataset list | SOX2 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 52.0 | 114.0 | 123.0 | 211.0 |
| 02 | 18.0 | 176.0 | 131.0 | 175.0 |
| 03 | 5.0 | 321.0 | 40.0 | 134.0 |
| 04 | 8.0 | 364.0 | 5.0 | 123.0 |
| 05 | 146.0 | 5.0 | 0.0 | 349.0 |
| 06 | 0.0 | 1.0 | 1.0 | 498.0 |
| 07 | 0.0 | 0.0 | 0.0 | 500.0 |
| 08 | 8.0 | 78.0 | 404.0 | 10.0 |
| 09 | 31.0 | 9.0 | 0.0 | 460.0 |
| 10 | 23.0 | 127.0 | 104.0 | 246.0 |
| 11 | 53.0 | 206.0 | 38.0 | 203.0 |
| 12 | 51.0 | 156.0 | 68.0 | 225.0 |
| 13 | 38.0 | 198.0 | 129.0 | 135.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.86 | -0.091 | -0.016 | 0.519 |
| 02 | -1.868 | 0.339 | 0.046 | 0.333 |
| 03 | -2.961 | 0.936 | -1.114 | 0.069 |
| 04 | -2.584 | 1.061 | -2.961 | -0.016 |
| 05 | 0.154 | -2.961 | -4.4 | 1.019 |
| 06 | -4.4 | -3.903 | -3.903 | 1.373 |
| 07 | -4.4 | -4.4 | -4.4 | 1.377 |
| 08 | -2.584 | -0.464 | 1.165 | -2.394 |
| 09 | -1.358 | -2.484 | -4.4 | 1.294 |
| 10 | -1.64 | 0.016 | -0.181 | 0.671 |
| 11 | -0.841 | 0.495 | -1.163 | 0.48 |
| 12 | -0.879 | 0.219 | -0.599 | 0.582 |
| 13 | -1.163 | 0.455 | 0.031 | 0.076 |