Model info
| Transcription factor | SOX2 (GeneCards) | ||||||||
| Model | SOX2_HUMAN.H11MO.1.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 16 | ||||||||
| Quality | A | ||||||||
| Motif rank | 1 | ||||||||
| Consensus | bYYWTTSTbhTKYhdW | ||||||||
| Best auROC (human) | 0.957 | ||||||||
| Best auROC (mouse) | 0.955 | ||||||||
| Peak sets in benchmark (human) | 67 | ||||||||
| Peak sets in benchmark (mouse) | 109 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | SOX-related factors {4.1.1} | ||||||||
| TF subfamily | Group B {4.1.1.2} | ||||||||
| HGNC | HGNC:11195 | ||||||||
| EntrezGene | GeneID:6657 (SSTAR profile) | ||||||||
| UniProt ID | SOX2_HUMAN | ||||||||
| UniProt AC | P48431 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | SOX2 expression | ||||||||
| ReMap ChIP-seq dataset list | SOX2 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 39.0 | 136.0 | 134.0 | 191.0 |
| 02 | 14.0 | 316.0 | 75.0 | 95.0 |
| 03 | 17.0 | 339.0 | 9.0 | 135.0 |
| 04 | 191.0 | 22.0 | 7.0 | 280.0 |
| 05 | 1.0 | 8.0 | 3.0 | 488.0 |
| 06 | 4.0 | 0.0 | 2.0 | 494.0 |
| 07 | 26.0 | 117.0 | 348.0 | 9.0 |
| 08 | 99.0 | 4.0 | 9.0 | 388.0 |
| 09 | 66.0 | 140.0 | 88.0 | 206.0 |
| 10 | 254.0 | 100.0 | 22.0 | 124.0 |
| 11 | 31.0 | 30.0 | 17.0 | 422.0 |
| 12 | 8.0 | 95.0 | 295.0 | 102.0 |
| 13 | 30.0 | 267.0 | 53.0 | 150.0 |
| 14 | 263.0 | 53.0 | 48.0 | 136.0 |
| 15 | 211.0 | 70.0 | 123.0 | 96.0 |
| 16 | 316.0 | 58.0 | 31.0 | 95.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -1.138 | 0.083 | 0.069 | 0.42 |
| 02 | -2.096 | 0.92 | -0.503 | -0.271 |
| 03 | -1.92 | 0.99 | -2.484 | 0.076 |
| 04 | 0.42 | -1.681 | -2.694 | 0.8 |
| 05 | -3.903 | -2.584 | -3.325 | 1.353 |
| 06 | -3.126 | -4.4 | -3.573 | 1.365 |
| 07 | -1.525 | -0.065 | 1.016 | -2.484 |
| 08 | -0.23 | -3.126 | -2.484 | 1.124 |
| 09 | -0.628 | 0.112 | -0.346 | 0.495 |
| 10 | 0.703 | -0.22 | -1.681 | -0.008 |
| 11 | -1.358 | -1.389 | -1.92 | 1.208 |
| 12 | -2.584 | -0.271 | 0.852 | -0.201 |
| 13 | -1.389 | 0.752 | -0.841 | 0.18 |
| 14 | 0.737 | -0.841 | -0.938 | 0.083 |
| 15 | 0.519 | -0.57 | -0.016 | -0.26 |
| 16 | 0.92 | -0.754 | -1.358 | -0.271 |