Model info
| Transcription factor | STAT3 (GeneCards) | ||||||||
| Model | STAT3_HUMAN.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 12 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | bvhTTCCCRKAA | ||||||||
| Best auROC (human) | 0.953 | ||||||||
| Best auROC (mouse) | 0.949 | ||||||||
| Peak sets in benchmark (human) | 36 | ||||||||
| Peak sets in benchmark (mouse) | 82 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | STAT factors {6.2.1} | ||||||||
| TF subfamily | STAT3 {6.2.1.0.3} | ||||||||
| HGNC | HGNC:11364 | ||||||||
| EntrezGene | GeneID:6774 (SSTAR profile) | ||||||||
| UniProt ID | STAT3_HUMAN | ||||||||
| UniProt AC | P40763 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | STAT3 expression | ||||||||
| ReMap ChIP-seq dataset list | STAT3 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 84.0 | 212.0 | 114.0 | 90.0 |
| 02 | 226.0 | 96.0 | 98.0 | 80.0 |
| 03 | 57.0 | 170.0 | 52.0 | 221.0 |
| 04 | 12.0 | 3.0 | 1.0 | 484.0 |
| 05 | 7.0 | 1.0 | 40.0 | 452.0 |
| 06 | 43.0 | 444.0 | 3.0 | 10.0 |
| 07 | 1.0 | 435.0 | 0.0 | 64.0 |
| 08 | 224.0 | 276.0 | 0.0 | 0.0 |
| 09 | 174.0 | 8.0 | 307.0 | 11.0 |
| 10 | 26.0 | 6.0 | 366.0 | 102.0 |
| 11 | 395.0 | 86.0 | 2.0 | 17.0 |
| 12 | 452.0 | 17.0 | 13.0 | 18.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.392 | 0.523 | -0.091 | -0.324 |
| 02 | 0.587 | -0.26 | -0.24 | -0.439 |
| 03 | -0.771 | 0.304 | -0.86 | 0.565 |
| 04 | -2.234 | -3.325 | -3.903 | 1.345 |
| 05 | -2.694 | -3.903 | -1.114 | 1.276 |
| 06 | -1.044 | 1.259 | -3.325 | -2.394 |
| 07 | -3.903 | 1.238 | -4.4 | -0.658 |
| 08 | 0.578 | 0.785 | -4.4 | -4.4 |
| 09 | 0.327 | -2.584 | 0.891 | -2.311 |
| 10 | -1.525 | -2.819 | 1.066 | -0.201 |
| 11 | 1.142 | -0.368 | -3.573 | -1.92 |
| 12 | 1.276 | -1.92 | -2.163 | -1.868 |