Transcription factor | TCF7 (GeneCards) | ||||||||
Model | TCF7_HUMAN.H11DI.0.A | ||||||||
Model type | Dinucleotide PWM | ||||||||
LOGO | |||||||||
LOGO (reverse complement) | |||||||||
Data source | ChIP-Seq | ||||||||
Model release | HOCOMOCOv11 | ||||||||
Model length | 17 | ||||||||
Quality | A | ||||||||
Motif rank | 0 | ||||||||
Consensus | nvnnvRSWTSAAAGvvn | ||||||||
Best auROC (human) | 0.871 | ||||||||
Best auROC (mouse) | 0.926 | ||||||||
Peak sets in benchmark (human) | 7 | ||||||||
Peak sets in benchmark (mouse) | 19 | ||||||||
Aligned words | 213 | ||||||||
TF family | TCF-7-related factors {4.1.3} | ||||||||
TF subfamily | TCF-7 (TCF-1) [1] {4.1.3.0.1} | ||||||||
HGNC | HGNC:11639 | ||||||||
EntrezGene | GeneID:6932 (SSTAR profile) | ||||||||
UniProt ID | TCF7_HUMAN | ||||||||
UniProt AC | P36402 (TFClass) | ||||||||
Comment | |||||||||
Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
Standard thresholds |
| ||||||||
GTEx tissue expression atlas | TCF7 expression | ||||||||
ReMap ChIP-seq dataset list | TCF7 datasets | ||||||||
Motifs in JASPAR |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 35.0 | 4.0 | 23.0 | 10.0 | 16.0 | 9.0 | 10.0 | 6.0 | 14.0 | 10.0 | 19.0 | 0.0 | 14.0 | 8.0 | 20.0 | 5.0 |
02 | 29.0 | 10.0 | 29.0 | 11.0 | 9.0 | 15.0 | 4.0 | 3.0 | 19.0 | 21.0 | 22.0 | 10.0 | 4.0 | 5.0 | 8.0 | 4.0 |
03 | 14.0 | 34.0 | 7.0 | 6.0 | 21.0 | 20.0 | 2.0 | 8.0 | 32.0 | 13.0 | 12.0 | 6.0 | 9.0 | 9.0 | 4.0 | 6.0 |
04 | 33.0 | 12.0 | 28.0 | 3.0 | 17.0 | 46.0 | 5.0 | 8.0 | 6.0 | 11.0 | 8.0 | 0.0 | 9.0 | 4.0 | 11.0 | 2.0 |
05 | 44.0 | 6.0 | 6.0 | 9.0 | 59.0 | 4.0 | 7.0 | 3.0 | 39.0 | 2.0 | 10.0 | 1.0 | 9.0 | 2.0 | 1.0 | 1.0 |
06 | 1.0 | 88.0 | 61.0 | 1.0 | 0.0 | 13.0 | 1.0 | 0.0 | 1.0 | 10.0 | 10.0 | 3.0 | 0.0 | 10.0 | 4.0 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 1.0 | 79.0 | 8.0 | 1.0 | 33.0 | 57.0 | 0.0 | 4.0 | 15.0 | 2.0 | 0.0 | 1.0 | 1.0 |
08 | 9.0 | 2.0 | 0.0 | 128.0 | 1.0 | 0.0 | 0.0 | 7.0 | 2.0 | 0.0 | 1.0 | 3.0 | 9.0 | 1.0 | 1.0 | 39.0 |
09 | 1.0 | 15.0 | 4.0 | 1.0 | 0.0 | 2.0 | 1.0 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 21.0 | 129.0 | 24.0 | 3.0 |
10 | 19.0 | 1.0 | 1.0 | 1.0 | 144.0 | 1.0 | 1.0 | 2.0 | 29.0 | 0.0 | 0.0 | 0.0 | 4.0 | 0.0 | 0.0 | 0.0 |
11 | 166.0 | 22.0 | 8.0 | 0.0 | 2.0 | 0.0 | 0.0 | 0.0 | 2.0 | 0.0 | 0.0 | 0.0 | 3.0 | 0.0 | 0.0 | 0.0 |
12 | 163.0 | 0.0 | 4.0 | 6.0 | 19.0 | 0.0 | 0.0 | 3.0 | 8.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
13 | 12.0 | 11.0 | 166.0 | 1.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 4.0 | 0.0 | 2.0 | 1.0 | 5.0 | 1.0 |
14 | 2.0 | 0.0 | 11.0 | 1.0 | 8.0 | 0.0 | 4.0 | 0.0 | 51.0 | 24.0 | 87.0 | 13.0 | 1.0 | 0.0 | 1.0 | 0.0 |
15 | 14.0 | 20.0 | 23.0 | 5.0 | 6.0 | 13.0 | 2.0 | 3.0 | 27.0 | 37.0 | 29.0 | 10.0 | 4.0 | 6.0 | 4.0 | 0.0 |
16 | 22.0 | 8.0 | 16.0 | 5.0 | 29.0 | 21.0 | 11.0 | 15.0 | 21.0 | 14.0 | 13.0 | 10.0 | 2.0 | 4.0 | 6.0 | 6.0 |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 0.998 | -1.1 | 0.583 | -0.231 | 0.227 | -0.333 | -0.231 | -0.721 | 0.096 | -0.231 | 0.395 | -3.669 | 0.096 | -0.446 | 0.446 | -0.893 |
02 | 0.812 | -0.231 | 0.812 | -0.139 | -0.333 | 0.163 | -1.1 | -1.363 | 0.395 | 0.494 | 0.54 | -0.231 | -1.1 | -0.893 | -0.446 | -1.1 |
03 | 0.096 | 0.97 | -0.574 | -0.721 | 0.494 | 0.446 | -1.72 | -0.446 | 0.91 | 0.024 | -0.054 | -0.721 | -0.333 | -0.333 | -1.1 | -0.721 |
04 | 0.94 | -0.054 | 0.778 | -1.363 | 0.286 | 1.269 | -0.893 | -0.446 | -0.721 | -0.139 | -0.446 | -3.669 | -0.333 | -1.1 | -0.139 | -1.72 |
05 | 1.225 | -0.721 | -0.721 | -0.333 | 1.517 | -1.1 | -0.574 | -1.363 | 1.106 | -1.72 | -0.231 | -2.28 | -0.333 | -1.72 | -2.28 | -2.28 |
06 | -2.28 | 1.915 | 1.55 | -2.28 | -3.669 | 0.024 | -2.28 | -3.669 | -2.28 | -0.231 | -0.231 | -1.363 | -3.669 | -0.231 | -1.1 | -3.669 |
07 | -2.28 | -3.669 | -3.669 | -2.28 | 1.807 | -0.446 | -2.28 | 0.94 | 1.482 | -3.669 | -1.1 | 0.163 | -1.72 | -3.669 | -2.28 | -2.28 |
08 | -0.333 | -1.72 | -3.669 | 2.288 | -2.28 | -3.669 | -3.669 | -0.574 | -1.72 | -3.669 | -2.28 | -1.363 | -0.333 | -2.28 | -2.28 | 1.106 |
09 | -2.28 | 0.163 | -1.1 | -2.28 | -3.669 | -1.72 | -2.28 | -3.669 | -3.669 | -1.72 | -3.669 | -3.669 | 0.494 | 2.296 | 0.625 | -1.363 |
10 | 0.395 | -2.28 | -2.28 | -2.28 | 2.406 | -2.28 | -2.28 | -1.72 | 0.812 | -3.669 | -3.669 | -3.669 | -1.1 | -3.669 | -3.669 | -3.669 |
11 | 2.548 | 0.54 | -0.446 | -3.669 | -1.72 | -3.669 | -3.669 | -3.669 | -1.72 | -3.669 | -3.669 | -3.669 | -1.363 | -3.669 | -3.669 | -3.669 |
12 | 2.529 | -3.669 | -1.1 | -0.721 | 0.395 | -3.669 | -3.669 | -1.363 | -0.446 | -3.669 | -3.669 | -3.669 | -3.669 | -3.669 | -3.669 | -3.669 |
13 | -0.054 | -0.139 | 2.548 | -2.28 | -3.669 | -3.669 | -3.669 | -3.669 | -3.669 | -3.669 | -1.1 | -3.669 | -1.72 | -2.28 | -0.893 | -2.28 |
14 | -1.72 | -3.669 | -0.139 | -2.28 | -0.446 | -3.669 | -1.1 | -3.669 | 1.372 | 0.625 | 1.903 | 0.024 | -2.28 | -3.669 | -2.28 | -3.669 |
15 | 0.096 | 0.446 | 0.583 | -0.893 | -0.721 | 0.024 | -1.72 | -1.363 | 0.742 | 1.053 | 0.812 | -0.231 | -1.1 | -0.721 | -1.1 | -3.669 |
16 | 0.54 | -0.446 | 0.227 | -0.893 | 0.812 | 0.494 | -0.139 | 0.163 | 0.494 | 0.096 | 0.024 | -0.231 | -1.72 | -1.1 | -0.721 | -0.721 |