Model info
| Transcription factor | TCF7L1 (GeneCards) | ||||||||
| Model | TF7L1_HUMAN.H11MO.0.B | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 13 | ||||||||
| Quality | B | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | dbbCTTTSAWSWb | ||||||||
| Best auROC (human) | 0.926 | ||||||||
| Best auROC (mouse) | 0.741 | ||||||||
| Peak sets in benchmark (human) | 10 | ||||||||
| Peak sets in benchmark (mouse) | 10 | ||||||||
| Aligned words | 500 | ||||||||
| TF family | TCF-7-related factors {4.1.3} | ||||||||
| TF subfamily | TCF-7L1 (TCF-3) [1] {4.1.3.0.2} | ||||||||
| HGNC | HGNC:11640 | ||||||||
| EntrezGene | GeneID:83439 (SSTAR profile) | ||||||||
| UniProt ID | TF7L1_HUMAN | ||||||||
| UniProt AC | Q9HCS4 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | TCF7L1 expression | ||||||||
| ReMap ChIP-seq dataset list | TCF7L1 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 120.0 | 69.0 | 111.0 | 200.0 |
| 02 | 39.0 | 140.0 | 165.0 | 156.0 |
| 03 | 55.0 | 204.0 | 106.0 | 135.0 |
| 04 | 11.0 | 402.0 | 24.0 | 63.0 |
| 05 | 3.0 | 23.0 | 1.0 | 473.0 |
| 06 | 0.0 | 26.0 | 6.0 | 468.0 |
| 07 | 5.0 | 0.0 | 5.0 | 490.0 |
| 08 | 21.0 | 87.0 | 360.0 | 32.0 |
| 09 | 447.0 | 10.0 | 9.0 | 34.0 |
| 10 | 185.0 | 3.0 | 6.0 | 306.0 |
| 11 | 40.0 | 191.0 | 248.0 | 21.0 |
| 12 | 86.0 | 49.0 | 27.0 | 338.0 |
| 13 | 36.0 | 154.0 | 137.0 | 173.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.04 | -0.584 | -0.117 | 0.465 |
| 02 | -1.138 | 0.112 | 0.275 | 0.219 |
| 03 | -0.805 | 0.485 | -0.163 | 0.076 |
| 04 | -2.311 | 1.16 | -1.6 | -0.673 |
| 05 | -3.325 | -1.64 | -3.903 | 1.322 |
| 06 | -4.4 | -1.525 | -2.819 | 1.311 |
| 07 | -2.961 | -4.4 | -2.961 | 1.357 |
| 08 | -1.725 | -0.357 | 1.05 | -1.328 |
| 09 | 1.265 | -2.394 | -2.484 | -1.27 |
| 10 | 0.388 | -3.325 | -2.819 | 0.888 |
| 11 | -1.114 | 0.42 | 0.679 | -1.725 |
| 12 | -0.368 | -0.918 | -1.489 | 0.987 |
| 13 | -1.215 | 0.206 | 0.091 | 0.322 |