TF7L1_HUMAN.H11MO.0.B motif - HOmo sapiens COmprehensive MOdel COllection

We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.

Model info

Transcription factor

TCF7L1
(GeneCards)

Model

TF7L1_HUMAN.H11MO.0.B

Model type

Mononucleotide PWM

LOGO

LOGO (reverse complement)

Data source

ChIP-Seq

Model release

HOCOMOCOv11

Model length

13

Quality

B

Motif rank

0

Consensus

dbbCTTTSAWSWb

Best auROC (human)

0.926

Best auROC (mouse)

0.741

Peak sets in benchmark (human)

10

Peak sets in benchmark (mouse)

10

Aligned words

500

TF family

TCF-7-related factors {4.1.3}

TF subfamily

TCF-7L1 (TCF-3) [1] {4.1.3.0.2}

HGNC

EntrezGene

GeneID:83439
(SSTAR profile)

UniProt ID

UniProt AC

Q9HCS4
(TFClass)

Comment

Downloads

pcm
pwm
alignment
threshold to P-value grid

Standard thresholds

P-value	Threshold
0.001	5.821865
0.0005	6.656915
0.0001	8.32433

GTEx tissue expression atlas

TCF7L1 expression

ReMap ChIP-seq dataset list

TCF7L1 datasets

Motifs in JASPAR

MA1421.1 (TCF7L1; Homo sapiens)

PCM

	A	C	G	T
01	120.0	69.0	111.0	200.0
02	39.0	140.0	165.0	156.0
03	55.0	204.0	106.0	135.0
04	11.0	402.0	24.0	63.0
05	3.0	23.0	1.0	473.0
06	0.0	26.0	6.0	468.0
07	5.0	0.0	5.0	490.0
08	21.0	87.0	360.0	32.0
09	447.0	10.0	9.0	34.0
10	185.0	3.0	6.0	306.0
11	40.0	191.0	248.0	21.0
12	86.0	49.0	27.0	338.0
13	36.0	154.0	137.0	173.0

PWM

	A	C	G	T
01	-0.04	-0.584	-0.117	0.465
02	-1.138	0.112	0.275	0.219
03	-0.805	0.485	-0.163	0.076
04	-2.311	1.16	-1.6	-0.673
05	-3.325	-1.64	-3.903	1.322
06	-4.4	-1.525	-2.819	1.311
07	-2.961	-4.4	-2.961	1.357
08	-1.725	-0.357	1.05	-1.328
09	1.265	-2.394	-2.484	-1.27
10	0.388	-3.325	-2.819	0.888
11	-1.114	0.42	0.679	-1.725
12	-0.368	-0.918	-1.489	0.987
13	-1.215	0.206	0.091	0.322