We, Russian scientists of the autosome team, are depressed by the dire events caused by Russian military actions in Ukraine.
We express our condolences to all affected people and sincerely hope for a prompt transition to peace.
Model info
Transcription factorTCF7L2
(GeneCards)
ModelTF7L2_HUMAN.H11DI.0.A
Model typeDinucleotide PWM
LOGO
LOGO (reverse complement)
Data sourceChIP-Seq
Model releaseHOCOMOCOv11
Model length15
Quality
A
Motif rank
0
ConsensusnbbCTTTSAWSYbbn
Best auROC (human)0.966
Best auROC (mouse)0.891
Peak sets in benchmark (human)46
Peak sets in benchmark (mouse)10
Aligned words507
TF familyTCF-7-related factors {4.1.3}
TF subfamilyTCF-7L2 (TCF-4) [1] {4.1.3.0.3}
HGNCHGNC:11641
EntrezGeneGeneID:6934
(SSTAR profile)
UniProt IDTF7L2_HUMAN
UniProt ACQ9NQB0
(TFClass)
Comment
Downloadspcm
pwm
alignment
threshold to P-value grid
Standard thresholds
P-value
Threshold
0.001 10.481360000000002
0.0005 12.405560000000001
0.0001 16.276110000000003
GTEx tissue expression atlas TCF7L2 expression
ReMap ChIP-seq dataset list TCF7L2 datasets
Motifs in JASPAR
PCM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
0110.033.047.018.011.025.014.032.018.059.029.028.014.067.062.033.0
022.023.020.08.017.0103.021.043.010.086.028.028.012.057.017.025.0
030.041.00.00.01.0225.03.040.01.082.00.03.05.085.09.05.0
041.00.00.06.07.012.00.0414.00.00.00.012.00.02.00.046.0
050.01.00.07.00.02.00.012.00.00.00.00.00.017.09.0452.0
060.00.00.00.03.00.00.017.00.00.01.08.02.02.03.0464.0
070.00.05.00.01.01.00.00.01.00.03.00.010.083.0379.017.0
0810.00.01.01.077.01.01.05.0342.05.06.034.013.01.01.02.0
09118.01.07.0316.00.02.00.05.01.00.01.07.010.02.02.028.0
1013.021.093.02.01.02.02.00.00.03.07.00.04.0192.0152.08.0
112.03.02.011.022.040.01.0155.023.036.022.0173.01.02.01.06.0
122.011.019.016.014.027.010.030.03.05.05.013.012.084.0145.0104.0
133.08.03.017.028.034.012.053.017.039.0105.018.014.037.056.056.0
149.020.022.011.036.042.05.035.023.047.043.063.023.038.053.030.0
PWM
AAACAGATCACCCGCTGAGCGGGTTATCTGTT
01-1.1140.0540.404-0.543-1.022-0.22-0.7880.023-0.5430.63-0.074-0.108-0.7880.7560.6790.054
02-2.584-0.302-0.439-1.328-0.5991.184-0.3920.316-1.1141.004-0.108-0.108-0.9380.595-0.599-0.22
03-4.40.269-4.4-4.4-3.1261.963-2.2340.244-3.1260.957-4.4-2.234-1.770.993-1.215-1.77
04-3.126-4.4-4.4-1.6-1.454-0.938-4.42.572-4.4-4.4-4.4-0.938-4.4-2.584-4.40.383
05-4.4-3.126-4.4-1.454-4.4-2.584-4.4-0.938-4.4-4.4-4.4-4.4-4.4-0.599-1.2152.66
06-4.4-4.4-4.4-4.4-2.234-4.4-4.4-0.599-4.4-4.4-3.126-1.328-2.584-2.584-2.2342.686
07-4.4-4.4-1.77-4.4-3.126-3.126-4.4-4.4-3.126-4.4-2.234-4.4-1.1140.9692.484-0.599
08-1.114-4.4-3.126-3.1260.894-3.126-3.126-1.772.382-1.77-1.60.083-0.86-3.126-3.126-2.584
091.32-3.126-1.4542.303-4.4-2.584-4.4-1.77-3.126-4.4-3.126-1.454-1.114-2.584-2.584-0.108
10-0.86-0.3921.082-2.584-3.126-2.584-2.584-4.4-4.4-2.234-1.454-4.4-1.9751.8051.572-1.328
11-2.584-2.234-2.584-1.022-0.3460.244-3.1261.592-0.3020.14-0.3461.701-3.126-2.584-3.126-1.6
12-2.584-1.022-0.49-0.658-0.788-0.144-1.114-0.04-2.234-1.77-1.77-0.86-0.9380.9811.5251.194
13-2.234-1.328-2.234-0.599-0.1080.083-0.9380.523-0.5990.2191.203-0.543-0.7880.1670.5780.578
14-1.215-0.439-0.346-1.0220.140.293-1.770.112-0.3020.4040.3160.695-0.3020.1930.523-0.04