Transcription factor | TCF7L2 (GeneCards) | ||||||||
Model | TF7L2_HUMAN.H11DI.0.A | ||||||||
Model type | Dinucleotide PWM | ||||||||
LOGO | |||||||||
LOGO (reverse complement) | |||||||||
Data source | ChIP-Seq | ||||||||
Model release | HOCOMOCOv11 | ||||||||
Model length | 15 | ||||||||
Quality | A | ||||||||
Motif rank | 0 | ||||||||
Consensus | nbbCTTTSAWSYbbn | ||||||||
Best auROC (human) | 0.966 | ||||||||
Best auROC (mouse) | 0.891 | ||||||||
Peak sets in benchmark (human) | 46 | ||||||||
Peak sets in benchmark (mouse) | 10 | ||||||||
Aligned words | 507 | ||||||||
TF family | TCF-7-related factors {4.1.3} | ||||||||
TF subfamily | TCF-7L2 (TCF-4) [1] {4.1.3.0.3} | ||||||||
HGNC | HGNC:11641 | ||||||||
EntrezGene | GeneID:6934 (SSTAR profile) | ||||||||
UniProt ID | TF7L2_HUMAN | ||||||||
UniProt AC | Q9NQB0 (TFClass) | ||||||||
Comment | |||||||||
Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
Standard thresholds |
| ||||||||
GTEx tissue expression atlas | TCF7L2 expression | ||||||||
ReMap ChIP-seq dataset list | TCF7L2 datasets | ||||||||
Motifs in JASPAR |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | 10.0 | 33.0 | 47.0 | 18.0 | 11.0 | 25.0 | 14.0 | 32.0 | 18.0 | 59.0 | 29.0 | 28.0 | 14.0 | 67.0 | 62.0 | 33.0 |
02 | 2.0 | 23.0 | 20.0 | 8.0 | 17.0 | 103.0 | 21.0 | 43.0 | 10.0 | 86.0 | 28.0 | 28.0 | 12.0 | 57.0 | 17.0 | 25.0 |
03 | 0.0 | 41.0 | 0.0 | 0.0 | 1.0 | 225.0 | 3.0 | 40.0 | 1.0 | 82.0 | 0.0 | 3.0 | 5.0 | 85.0 | 9.0 | 5.0 |
04 | 1.0 | 0.0 | 0.0 | 6.0 | 7.0 | 12.0 | 0.0 | 414.0 | 0.0 | 0.0 | 0.0 | 12.0 | 0.0 | 2.0 | 0.0 | 46.0 |
05 | 0.0 | 1.0 | 0.0 | 7.0 | 0.0 | 2.0 | 0.0 | 12.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 17.0 | 9.0 | 452.0 |
06 | 0.0 | 0.0 | 0.0 | 0.0 | 3.0 | 0.0 | 0.0 | 17.0 | 0.0 | 0.0 | 1.0 | 8.0 | 2.0 | 2.0 | 3.0 | 464.0 |
07 | 0.0 | 0.0 | 5.0 | 0.0 | 1.0 | 1.0 | 0.0 | 0.0 | 1.0 | 0.0 | 3.0 | 0.0 | 10.0 | 83.0 | 379.0 | 17.0 |
08 | 10.0 | 0.0 | 1.0 | 1.0 | 77.0 | 1.0 | 1.0 | 5.0 | 342.0 | 5.0 | 6.0 | 34.0 | 13.0 | 1.0 | 1.0 | 2.0 |
09 | 118.0 | 1.0 | 7.0 | 316.0 | 0.0 | 2.0 | 0.0 | 5.0 | 1.0 | 0.0 | 1.0 | 7.0 | 10.0 | 2.0 | 2.0 | 28.0 |
10 | 13.0 | 21.0 | 93.0 | 2.0 | 1.0 | 2.0 | 2.0 | 0.0 | 0.0 | 3.0 | 7.0 | 0.0 | 4.0 | 192.0 | 152.0 | 8.0 |
11 | 2.0 | 3.0 | 2.0 | 11.0 | 22.0 | 40.0 | 1.0 | 155.0 | 23.0 | 36.0 | 22.0 | 173.0 | 1.0 | 2.0 | 1.0 | 6.0 |
12 | 2.0 | 11.0 | 19.0 | 16.0 | 14.0 | 27.0 | 10.0 | 30.0 | 3.0 | 5.0 | 5.0 | 13.0 | 12.0 | 84.0 | 145.0 | 104.0 |
13 | 3.0 | 8.0 | 3.0 | 17.0 | 28.0 | 34.0 | 12.0 | 53.0 | 17.0 | 39.0 | 105.0 | 18.0 | 14.0 | 37.0 | 56.0 | 56.0 |
14 | 9.0 | 20.0 | 22.0 | 11.0 | 36.0 | 42.0 | 5.0 | 35.0 | 23.0 | 47.0 | 43.0 | 63.0 | 23.0 | 38.0 | 53.0 | 30.0 |
AA | AC | AG | AT | CA | CC | CG | CT | GA | GC | GG | GT | TA | TC | TG | TT | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
01 | -1.114 | 0.054 | 0.404 | -0.543 | -1.022 | -0.22 | -0.788 | 0.023 | -0.543 | 0.63 | -0.074 | -0.108 | -0.788 | 0.756 | 0.679 | 0.054 |
02 | -2.584 | -0.302 | -0.439 | -1.328 | -0.599 | 1.184 | -0.392 | 0.316 | -1.114 | 1.004 | -0.108 | -0.108 | -0.938 | 0.595 | -0.599 | -0.22 |
03 | -4.4 | 0.269 | -4.4 | -4.4 | -3.126 | 1.963 | -2.234 | 0.244 | -3.126 | 0.957 | -4.4 | -2.234 | -1.77 | 0.993 | -1.215 | -1.77 |
04 | -3.126 | -4.4 | -4.4 | -1.6 | -1.454 | -0.938 | -4.4 | 2.572 | -4.4 | -4.4 | -4.4 | -0.938 | -4.4 | -2.584 | -4.4 | 0.383 |
05 | -4.4 | -3.126 | -4.4 | -1.454 | -4.4 | -2.584 | -4.4 | -0.938 | -4.4 | -4.4 | -4.4 | -4.4 | -4.4 | -0.599 | -1.215 | 2.66 |
06 | -4.4 | -4.4 | -4.4 | -4.4 | -2.234 | -4.4 | -4.4 | -0.599 | -4.4 | -4.4 | -3.126 | -1.328 | -2.584 | -2.584 | -2.234 | 2.686 |
07 | -4.4 | -4.4 | -1.77 | -4.4 | -3.126 | -3.126 | -4.4 | -4.4 | -3.126 | -4.4 | -2.234 | -4.4 | -1.114 | 0.969 | 2.484 | -0.599 |
08 | -1.114 | -4.4 | -3.126 | -3.126 | 0.894 | -3.126 | -3.126 | -1.77 | 2.382 | -1.77 | -1.6 | 0.083 | -0.86 | -3.126 | -3.126 | -2.584 |
09 | 1.32 | -3.126 | -1.454 | 2.303 | -4.4 | -2.584 | -4.4 | -1.77 | -3.126 | -4.4 | -3.126 | -1.454 | -1.114 | -2.584 | -2.584 | -0.108 |
10 | -0.86 | -0.392 | 1.082 | -2.584 | -3.126 | -2.584 | -2.584 | -4.4 | -4.4 | -2.234 | -1.454 | -4.4 | -1.975 | 1.805 | 1.572 | -1.328 |
11 | -2.584 | -2.234 | -2.584 | -1.022 | -0.346 | 0.244 | -3.126 | 1.592 | -0.302 | 0.14 | -0.346 | 1.701 | -3.126 | -2.584 | -3.126 | -1.6 |
12 | -2.584 | -1.022 | -0.49 | -0.658 | -0.788 | -0.144 | -1.114 | -0.04 | -2.234 | -1.77 | -1.77 | -0.86 | -0.938 | 0.981 | 1.525 | 1.194 |
13 | -2.234 | -1.328 | -2.234 | -0.599 | -0.108 | 0.083 | -0.938 | 0.523 | -0.599 | 0.219 | 1.203 | -0.543 | -0.788 | 0.167 | 0.578 | 0.578 |
14 | -1.215 | -0.439 | -0.346 | -1.022 | 0.14 | 0.293 | -1.77 | 0.112 | -0.302 | 0.404 | 0.316 | 0.695 | -0.302 | 0.193 | 0.523 | -0.04 |