Model info
| Transcription factor | TWIST1 (GeneCards) | ||||||||
| Model | TWST1_HUMAN.H11MO.0.A | ||||||||
| Model type | Mononucleotide PWM | ||||||||
| LOGO |  | ||||||||
| LOGO (reverse complement) |  | ||||||||
| Data source | ChIP-Seq | ||||||||
| Model release | HOCOMOCOv11 | ||||||||
| Model length | 17 | ||||||||
| Quality | A | ||||||||
| Motif rank | 0 | ||||||||
| Consensus | vCAKMTGKWWbbvRTYW | ||||||||
| Best auROC (human) | 0.969 | ||||||||
| Best auROC (mouse) | 0.539 | ||||||||
| Peak sets in benchmark (human) | 9 | ||||||||
| Peak sets in benchmark (mouse) | 8 | ||||||||
| Aligned words | 497 | ||||||||
| TF family | Tal-related factors {1.2.3} | ||||||||
| TF subfamily | Twist-like factors {1.2.3.2} | ||||||||
| HGNC | HGNC:12428 | ||||||||
| EntrezGene | GeneID:7291 (SSTAR profile) | ||||||||
| UniProt ID | TWST1_HUMAN | ||||||||
| UniProt AC | Q15672 (TFClass) | ||||||||
| Comment | |||||||||
| Downloads | pcm
pwm alignment threshold to P-value grid | ||||||||
| Standard thresholds |
| ||||||||
| GTEx tissue expression atlas | TWIST1 expression | ||||||||
| ReMap ChIP-seq dataset list | TWIST1 datasets | ||||||||
| Motifs in JASPAR |
PCM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 252.0 | 133.0 | 77.0 | 35.0 |
| 02 | 35.0 | 432.0 | 14.0 | 16.0 |
| 03 | 459.0 | 7.0 | 17.0 | 14.0 |
| 04 | 5.0 | 41.0 | 91.0 | 360.0 |
| 05 | 98.0 | 349.0 | 40.0 | 10.0 |
| 06 | 1.0 | 2.0 | 1.0 | 493.0 |
| 07 | 0.0 | 4.0 | 481.0 | 12.0 |
| 08 | 13.0 | 72.0 | 266.0 | 146.0 |
| 09 | 145.0 | 37.0 | 43.0 | 272.0 |
| 10 | 142.0 | 47.0 | 35.0 | 273.0 |
| 11 | 58.0 | 133.0 | 59.0 | 247.0 |
| 12 | 30.0 | 179.0 | 45.0 | 243.0 |
| 13 | 216.0 | 145.0 | 80.0 | 56.0 |
| 14 | 390.0 | 28.0 | 44.0 | 35.0 |
| 15 | 8.0 | 17.0 | 26.0 | 446.0 |
| 16 | 46.0 | 92.0 | 17.0 | 342.0 |
| 17 | 326.0 | 18.0 | 18.0 | 135.0 |
PWM
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.701 | 0.067 | -0.471 | -1.236 |
| 02 | -1.236 | 1.237 | -2.091 | -1.97 |
| 03 | 1.298 | -2.689 | -1.914 | -2.091 |
| 04 | -2.955 | -1.084 | -0.307 | 1.056 |
| 05 | -0.234 | 1.025 | -1.108 | -2.388 |
| 06 | -3.898 | -3.567 | -3.898 | 1.369 |
| 07 | -4.395 | -3.121 | 1.344 | -2.228 |
| 08 | -2.157 | -0.537 | 0.755 | 0.159 |
| 09 | 0.153 | -1.183 | -1.038 | 0.777 |
| 10 | 0.132 | -0.952 | -1.236 | 0.78 |
| 11 | -0.748 | 0.067 | -0.731 | 0.681 |
| 12 | -1.383 | 0.361 | -0.994 | 0.665 |
| 13 | 0.548 | 0.153 | -0.433 | -0.782 |
| 14 | 1.135 | -1.449 | -1.016 | -1.236 |
| 15 | -2.578 | -1.914 | -1.519 | 1.269 |
| 16 | -0.973 | -0.296 | -1.914 | 1.005 |
| 17 | 0.957 | -1.862 | -1.862 | 0.082 |